N-Desethyl Sunitinib
- Product Name
- N-Desethyl Sunitinib
- CAS No.
- 356068-97-8
- Chemical Name
- N-Desethyl Sunitinib
- Synonyms
- SU11662;HY-10873;SU-11662;SU 11662;N-Desethyl Sunitinib;Sunitinib N-Desethyl Imp;SU11662;SU 11662;SU-11662;N-Desethylsunitinib TFA Salt;Sunitinib N-Desethyl Impurity;Sunitinib Des Ethyl Impurity-A
- CBNumber
- CB11565651
- Molecular Formula
- C20H23FN4O2
- Formula Weight
- 370.42
- MOL File
- 356068-97-8.mol
N-Desethyl Sunitinib Property
- Melting point:
- 268-270?C
- Boiling point:
- 574.4±50.0 °C(Predicted)
- Density
- 1.265±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly, Heated), Methanol (Sparingly)
- form
- Solid
- pka
- 11.71±0.20(Predicted)
- color
- Yellow to Dark Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
N-Bromosuccinimide Price
- Product number
- SML3117
- Product name
- N-Desethyl sunitinib hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $142
- Updated
- 2023/06/20
- Product number
- SML3117
- Product name
- N-Desethyl sunitinib hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $456
- Updated
- 2023/06/20
- Product number
- 22292
- Product name
- N-desethyl Sunitinib
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 22292
- Product name
- N-desethyl Sunitinib
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 22292
- Product name
- N-desethyl Sunitinib
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $283
- Updated
- 2024/03/01
N-Desethyl Sunitinib Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Uses
A metabolite of Sunitinib (S820000).
Biological Activity
N-Desethyl sunitinib is a multi-target tyrosine kinase inhibitor th at is a major active metabolite of an anticancer drug sunitinib. N-Desethyl sunitinib has a similar kinase inhibitory effect as sunitinib. In patients, plasma sunitinib and N-desethyl sunitinib accounts for 42% and 24%, respectively. Thus N-desethyl sunitinib accounts for one third of the therapeutic effect of oral sunitinib.
N-Desethyl Sunitinib Preparation Products And Raw materials
Raw materials
Preparation Products
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