ChemicalBook > CAS DataBase List > 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

Product Name
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
CAS No.
452105-33-8
Chemical Name
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
Synonyms
Sunitinib Malate 1;Sunitinib Carbaxylic Acid;Sunitinib Process Impurity 1;Sunitinib Carboxylic Acid Impurity;5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid;5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid;5-[(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-carboxylic Acid;1H-Pyrrole-3-carboxylic acid, 5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-;5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-carboxylic acid;5(5Fluoro2oxo1,2dihydroindol3ylidenemethyl)2,4dimethyl1Hpyrrole3carboxylic Acid,5 (5 Fluoro 2 oxo 1,2 dihydro indol 3 ylidenemethyl) 2,4 dimethyl 1H pyrrole 3 carboxylic Acid
CBNumber
CB41175932
Molecular Formula
C16H13FN2O3
Formula Weight
300.2844232
MOL File
452105-33-8.mol
More
Less

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Property

Melting point:
>295°C (dec.)
Boiling point:
588.4±50.0 °C(Predicted)
Density 
1.454±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
6.04±0.50(Predicted)
color 
Yellow to Dark Red
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
F595150
Product name
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylicAcid
Packaging
50mg
Price
$285
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0105002
Product name
5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID
Purity
95.00%
Packaging
25MG
Price
$721.88
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
10325
Product name
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylicAcid
Packaging
25mg
Price
$875
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0105002
Product name
5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID
Purity
95.00%
Packaging
250MG
Price
$1732.5
Updated
2021/12/16
AvaChem
Product number
2596
Product name
5-(5-Fluoro-2-oxoindolin-3-ylidene)methyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Packaging
1g
Price
$650
Updated
2021/12/16
More
Less

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Chemical Properties,Usage,Production

Uses

Sunitinib intermediate.

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
Medical Isotopes
Tel
--
Fax
--
Email
stohler@medicalisotopes.com
Country
United States
ProdList
6181
Advantage
68

452105-33-8, 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic AcidRelated Search:


  • 5-[(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-carboxylic Acid
  • Sunitinib Malate 1
  • 5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
  • Sunitinib Carboxylic Acid Impurity
  • 1H-Pyrrole-3-carboxylic acid, 5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-
  • 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-carboxylic acid
  • 5(5Fluoro2oxo1,2dihydroindol3ylidenemethyl)2,4dimethyl1Hpyrrole3carboxylic Acid,5 (5 Fluoro 2 oxo 1,2 dihydro indol 3 ylidenemethyl) 2,4 dimethyl 1H pyrrole 3 carboxylic Acid
  • Sunitinib Carbaxylic Acid
  • 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
  • Sunitinib Process Impurity 1
  • 452105-33-8
  • Intermediates & Fine Chemicals
  • Pharmaceuticals