ChemicalBook > CAS DataBase List > O-Desmethyl Metoprolol

O-Desmethyl Metoprolol

Product Name
O-Desmethyl Metoprolol
CAS No.
62572-94-5
Chemical Name
O-Desmethyl Metoprolol
Synonyms
H 105/22;SL 80-008;SL 80-0088;Metoprolol-8;Betaxolol-001;O-demethylmetoprolo;Metoprolol-EP-Imp-H;Betaxolol Impurity 1;Betaxolol Impurity B;Metoprolol Impurity 8
CBNumber
CB41176641
Molecular Formula
C14H23NO3
Formula Weight
253.34
MOL File
62572-94-5.mol
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O-Desmethyl Metoprolol Property

Melting point:
70-720C
Boiling point:
424.6±40.0 °C(Predicted)
Density 
1.085±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
13.88±0.20(Predicted)
color 
White to Off-White
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Safety

Toxicity
LD50 intravenous in dog: 150mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21787
Product name
O-Desmethyl Metoprolol
Purity
≥95%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
21787
Product name
O-Desmethyl Metoprolol
Purity
≥95%
Packaging
5mg
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
21787
Product name
O-Desmethyl Metoprolol
Purity
≥95%
Packaging
10mg
Price
$380
Updated
2024/03/01
Usbiological
Product number
008628
Product name
O-Desmethyl Metoprolol
Packaging
5mg
Price
$425
Updated
2021/12/16
TRC
Product number
D292073
Product name
O-DesmethylMetoprolol
Packaging
50mg
Price
$1155
Updated
2021/12/16
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O-Desmethyl Metoprolol Chemical Properties,Usage,Production

Description

O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol . It is formed by metabolism of metoprolol by the cytochrome P450 (CYP) isoform CYP2D6 in vivo.

Chemical Properties

Off-White Solid

Uses

O-Desmethyl Metoprolol (Metoprolol EP Impurity H) is a metabolite of Metoprolol.

O-Desmethyl Metoprolol Preparation Products And Raw materials

Raw materials

Preparation Products

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O-Desmethyl Metoprolol Suppliers

Canada 1 China 71 India 11 Spain 1 United Kingdom 1 United States 9 Global 94
Tianjin shijia biomedical technology co., LTD
Tel
15022261580;411316762
Email
tjshj1212@163.com
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China
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
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76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
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50
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
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China
ProdList
4969
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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010-52878169 15701683040
Email
sales@bjcomparison.com
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China
ProdList
4689
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58
Clearsynth Labs Limited
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+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9685
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58
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1958
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55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
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China
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17981
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
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sales@reading-chemicals.com
Country
China
ProdList
15185
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Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
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50

62572-94-5, O-Desmethyl MetoprololRelated Search:

3-[2-Hydroxy-3-[4-(2-methoxyethyl)phenoxy]propoxy]-1-isopropylamino-2-propanol 1-(2-methoxyethyl)-4-nitrobenzene 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL H 128/80 rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol 1,3-Bis[(1-Methylethyl)aMino]-2-propanol Dihydrochloride 1-(isopropylamino)-3-phenoxy-2-propanol 3-[4-(2-Methoxyethyl)phenoxy]- 2-Propanol, 1-[2-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]- p-(2-Methoxyethyl) phenol 1,1′-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol hydrochloride C-Desmethyl Metoprolol 4-Hydroxyphenethyl alcohol Metoprolol Impurity 1 Metoprolol EP IMpurity M 1-[4-(2-Methoxyethenyl)phenoxy]-3-[(1-Methylethyl)aMino]-2-propanol 1,1[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol (Mixture of diastereomers) LEVOBETAXOLOL

  • (-4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylethyl Alcohol
  • (-O-Demethylmetoprolol
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneethanol
  • H 105/22
  • O-Desmethyl Metoprolol
  • SL 80-008
  • O-demethylmetoprolo
  • Imp. H (EP):(2RS)-1-[4-(2-Hydroxyethyl)-phenoxy]-3-[(1-methylethyl)amino]propan-2-ol
  • Metoprolol-EP-Imp-H
  • Metoprolol EP Impurity H (Betaxolol EP Impurity B)
  • 1-(4-(2-hydroxyethyl)phenoxy)
  • Metoprolol-8
  • Metoprolol impurity 6/Metoprolol EP Impurity H/O-Desmethyl Metoprolol/1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol
  • Metoprolol Impurity 8
  • Betaxolol Impurity 1
  • SL 80-0088
  • Metoprolol Tartrate EP IMpurity-H
  • Metoprolol EP IMpurity H
  • 1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol
  • (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol
  • Betaxolol-001
  • Betaxolol EP Impurity B
  • Betaxolol Impurity 2(Betaxolol EP Impurity B)
  • Metoprolol Impurity 8(Metoprolol EP Impurity H)
  • (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]
  • Benzeneethanol, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
  • 13/5000 Metoprolol tartrate impurity H
  • Metoprolol EP Impurity H (O-Desmethyl Metoprolol)
  • Betaxolol Impurity B
  • Metoprolol Succinate Impurity H
  • Metoprolol Tartrate Impurity H
  • Metoprolol Succinate EP Impurity H
  • Betaxolol Hydrochloride Impurity B
  • Betaxolol Hydrochloride EP Impurity B
  • Metoprolol EP Impurity 8
  • Betaxolol EP Impurity B (Metoprolol EP Impurity H)
  • 62572-94-5
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals