ChemicalBook > CAS DataBase List > Ametantrone

Ametantrone

Product Name
Ametantrone
CAS No.
64862-96-0
Chemical Name
Ametantrone
Synonyms
HAQ;CS-1411;NSC 290813;NSC 196473;NSC-287513;Ametantrone;Ametantrone, >=98%;ametantrone diacetate.;AMetantrone(NSC 196473);1,4-BIS(2-(2-HYDROXYETHYLAMINO)ETHYLAMINO)ANTHRACENE-9,10-DIOL
CBNumber
CB41177996
Molecular Formula
C22H28N4O4
Formula Weight
412.48
MOL File
64862-96-0.mol
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Ametantrone Property

Melting point:
156-158 °C
Boiling point:
531.92°C (rough estimate)
Density 
1.2344 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
Store at -20°C
solubility 
DMSO: soluble
form 
A crystalline solid
pka
14.47±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22924
Product name
Ametantrone
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
22924
Product name
Ametantrone
Packaging
5mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
22924
Product name
Ametantrone
Packaging
10mg
Price
$341
Updated
2024/03/01
AK Scientific
Product number
0251CA
Product name
Ametantrone
Packaging
1mg
Price
$147
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009086
Product name
AMETANTRONE
Purity
95.00%
Packaging
0.1G
Price
$489.5
Updated
2021/12/16
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Ametantrone Chemical Properties,Usage,Production

Description

Ametantrone is an inhibitor of topoisomerase II. It induces double-strand breaks in SV40 DNA in the presence, but not absence, of topoisomerase II and induces single-strand breaks in DNA in NCI H187 cells. It also induces interstrand DNA cross-links in HeLa S3 cells at a minimum concentration of 4.1 μM. Ametantrone is cytotoxic to NCI H187 and HL-60 cells (IC50s = 112 and 0.44 μM, respectively). It inhibits tumor growth in a Ridgway osteogenic sarcoma mouse model when administered at a dose of 5 mg/kg, however, it increases tumor growth in mouse models of mammary adenocarcinoma and colon adenocarcinoma 11a.

Ametantrone Preparation Products And Raw materials

Raw materials

Preparation Products

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Ametantrone Suppliers

AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
Country
China
ProdList
1785
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6463
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862,442785678,326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
Lancrix Chemicals
Tel
86-21-50817262
Fax
86-21-57712035
Email
sales@lancrix.com
Country
China
ProdList
1502
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
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View Lastest Price from Ametantrone manufacturers

Career Henan Chemical Co
Product
Ametantrone 64862-96-0
Price
US $0.50/g
Min. Order
1g
Purity
98%min
Supply Ability
10g,100g,1kg
Release date
2020-01-09

64862-96-0, AmetantroneRelated Search:


  • Ametantrone
  • 1,4-Bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthraquinone
  • HAQ
  • NSC-287513
  • NSC 196473
  • NSC 290813
  • AMetantrone(NSC 196473)
  • 1,4-BIS(2-(2-HYDROXYETHYLAMINO)ETHYLAMINO)ANTHRACENE-9,10-DIOL
  • Ametantrone, >=98%
  • 9,10-Anthracenedione,1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-
  • CS-1411
  • ametantrone diacetate.
  • CI-881;NSC 196473;NSC 287513;NSC-196473;NSC-287513;AMETANTRONE DIACETATE.
  • 64862-96-0