Ametantrone

ChemicalBook > CAS DataBase List > Ametantrone

Product Name: Ametantrone
CAS No.: 64862-96-0
Chemical Name: Ametantrone
Synonyms: HAQ;CS-1411;NSC 290813;NSC 196473;NSC-287513;Ametantrone;Ametantrone, >=98%;ametantrone diacetate.;AMetantrone(NSC 196473);1,4-BIS(2-(2-HYDROXYETHYLAMINO)ETHYLAMINO)ANTHRACENE-9,10-DIOL
CBNumber: CB41177996
Molecular Formula: C22H28N4O4
Formula Weight: 412.48
MOL File: 64862-96-0.mol

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Ametantrone Property

Melting point:: 156-158 °C
Boiling point:: 531.92°C (rough estimate)
Density: 1.2344 (rough estimate)
refractive index: 1.6500 (estimate)
storage temp.: Store at -20°C
solubility: DMSO: soluble
form: A crystalline solid
pka: 14.47±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22924
Product name: Ametantrone
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 22924
Product name: Ametantrone
Packaging: 5mg
Price: $183
Updated: 2024/03/01

Cayman Chemical

Product number: 22924
Product name: Ametantrone
Packaging: 10mg
Price: $341
Updated: 2024/03/01

AK Scientific

Product number: 0251CA
Product name: Ametantrone
Packaging: 1mg
Price: $147
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009086
Product name: AMETANTRONE
Purity: 95.00%
Packaging: 0.1G
Price: $489.5
Updated: 2021/12/16

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Ametantrone Chemical Properties,Usage,Production

Description

Ametantrone is an inhibitor of topoisomerase II. It induces double-strand breaks in SV40 DNA in the presence, but not absence, of topoisomerase II and induces single-strand breaks in DNA in NCI H187 cells. It also induces interstrand DNA cross-links in HeLa S3 cells at a minimum concentration of 4.1 μM. Ametantrone is cytotoxic to NCI H187 and HL-60 cells (IC₅₀s = 112 and 0.44 μM, respectively). It inhibits tumor growth in a Ridgway osteogenic sarcoma mouse model when administered at a dose of 5 mg/kg, however, it increases tumor growth in mouse models of mammary adenocarcinoma and colon adenocarcinoma 11a.

Ametantrone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ametantrone manufacturers

Career Henan Chemical Co

Product: Ametantrone 64862-96-0
Price: US $0.50/g
Min. Order: 1g
Purity: 98%min
Supply Ability: 10g,100g,1kg
Release date: 2020-01-09

64862-96-0, AmetantroneRelated Search:

Mitoxantrone 1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione MITOXANTRONE, [3H(G)] Ametantrone

Ametantrone

1,4-Bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthraquinone

HAQ

NSC-287513

NSC 196473

NSC 290813

AMetantrone(NSC 196473)

1,4-BIS(2-(2-HYDROXYETHYLAMINO)ETHYLAMINO)ANTHRACENE-9,10-DIOL

Ametantrone, >=98%

9,10-Anthracenedione,1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-

CS-1411

ametantrone diacetate.

CI-881;NSC 196473;NSC 287513;NSC-196473;NSC-287513;AMETANTRONE DIACETATE.

64862-96-0