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Fexinidazole

Product Name
Fexinidazole
CAS No.
59729-37-2
Chemical Name
Fexinidazole
Synonyms
HOE-239;Fexinidazole;HOE-239;HOE239;HOE 239;Fexinidazole (HOE 239);Fexinidazole, 10 mM in DMSO;1-Methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-1H-imidazole;1H-Imidazole, 1-methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-;antitrypanosomal,nitroimidazole,sleeping,HOE239,Fexinidazole,T.brucei,sickness,orally,HOE-239,Inhibitor,inhibit,HAT,Parasite
CBNumber
CB41178746
Molecular Formula
C12H13N3O3S
Formula Weight
279.31
MOL File
59729-37-2.mol
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Fexinidazole Property

Boiling point:
501 °C
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMF: 20 mg/mL; DMF:PBS (pH 7.2) (1:8): 0.11 mg/mL; DMSO: 10 mg/mL; Ethanol: 0.2 mg/mL
form 
A crystalline solid
pka
1.82±0.25(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18393
Product name
Fexinidazole
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
18393
Product name
Fexinidazole
Purity
≥98%
Packaging
5mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
18393
Product name
Fexinidazole
Purity
≥98%
Packaging
10mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
18393
Product name
Fexinidazole
Purity
≥98%
Packaging
25mg
Price
$692
Updated
2024/03/01
ChemScene
Product number
CS-5535
Product name
Fexinidazole
Purity
99.92%
Packaging
100mg
Price
$810
Updated
2021/12/16
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Fexinidazole Chemical Properties,Usage,Production

Uses

Fexinidazole is a medication used in the treatment of African trypanosomiasis caused by trypanosoma brucei gambiense. An antitrypanosomal agent. It also functions as a medication used against the main species that cause visceral and cutaneous new World leishmaniasis.

Biological Activity

Anti Trypanosoma, Leishmania agent.', 'Fexinidazole is a potent anti-Trypanosoma agent. Trypanosoma species human protozoan pathogens are responsible for sleeping sickness and Chagas disease. In vivo, fexinidazole is oxidized to sulfoxide and sulfone metabolites th at are effective in blocking the progression of the parasitic disease visceral leishmaniasis. The mechanism of action appears to be by reductive activation via an NADH-dependent nitroreductase expressed by the parasites.

Fexinidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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Fexinidazole Suppliers

Target molecule Corp.
Tel
857-239-0968
Fax
857-239-8801
Email
service1@targetmol.com
Country
United States
ProdList
2559
Advantage
60
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-(817)863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
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View Lastest Price from Fexinidazole manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Fexinidazole 59729-37-2
Price
US $250.60/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
5000kg
Release date
2024-08-21

59729-37-2, FexinidazoleRelated Search:


  • 1-Methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-1H-imidazole
  • HOE-239
  • Fexinidazole
  • Fexinidazole (HOE 239)
  • HOE-239;HOE239;HOE 239
  • antitrypanosomal,nitroimidazole,sleeping,HOE239,Fexinidazole,T.brucei,sickness,orally,HOE-239,Inhibitor,inhibit,HAT,Parasite
  • 1H-Imidazole, 1-methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-
  • Fexinidazole, 10 mM in DMSO
  • 59729-37-2
  • Inhibitors
  • apis