Fexinidazole
- Product Name
- Fexinidazole
- CAS No.
- 59729-37-2
- Chemical Name
- Fexinidazole
- Synonyms
- HOE-239;Fexinidazole;HOE-239;HOE239;HOE 239;Fexinidazole (HOE 239);Fexinidazole, 10 mM in DMSO;1-Methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-1H-imidazole;1H-Imidazole, 1-methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-;antitrypanosomal,nitroimidazole,sleeping,HOE239,Fexinidazole,T.brucei,sickness,orally,HOE-239,Inhibitor,inhibit,HAT,Parasite
- CBNumber
- CB41178746
- Molecular Formula
- C12H13N3O3S
- Formula Weight
- 279.31
- MOL File
- 59729-37-2.mol
Fexinidazole Property
- Boiling point:
- 501 °C
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMF: 20 mg/mL; DMF:PBS (pH 7.2) (1:8): 0.11 mg/mL; DMSO: 10 mg/mL; Ethanol: 0.2 mg/mL
- form
- A crystalline solid
- pka
- 1.82±0.25(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 18393
- Product name
- Fexinidazole
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 18393
- Product name
- Fexinidazole
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 18393
- Product name
- Fexinidazole
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $341
- Updated
- 2024/03/01
- Product number
- 18393
- Product name
- Fexinidazole
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $692
- Updated
- 2024/03/01
- Product number
- CS-5535
- Product name
- Fexinidazole
- Purity
- 99.92%
- Packaging
- 100mg
- Price
- $810
- Updated
- 2021/12/16
Fexinidazole Chemical Properties,Usage,Production
Uses
Fexinidazole is a medication used in the treatment of African trypanosomiasis caused by trypanosoma brucei gambiense. An antitrypanosomal agent. It also functions as a medication used against the main species that cause visceral and cutaneous new World leishmaniasis.
Biological Activity
Anti Trypanosoma, Leishmania agent.', 'Fexinidazole is a potent anti-Trypanosoma agent. Trypanosoma species human protozoan pathogens are responsible for sleeping sickness and Chagas disease. In vivo, fexinidazole is oxidized to sulfoxide and sulfone metabolites th at are effective in blocking the progression of the parasitic disease visceral leishmaniasis. The mechanism of action appears to be by reductive activation via an NADH-dependent nitroreductase expressed by the parasites.
Fexinidazole Preparation Products And Raw materials
Raw materials
Preparation Products
Fexinidazole Suppliers
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View Lastest Price from Fexinidazole manufacturers
- Product
- Fexinidazole 59729-37-2
- Price
- US $250.60/KG
- Min. Order
- 1KG
- Purity
- 99.5%
- Supply Ability
- 5000kg
- Release date
- 2024-08-21