ChemicalBook > CAS DataBase List > PROCATEROL HYDROCHLORIDE

PROCATEROL HYDROCHLORIDE

Product Name: PROCATEROL HYDROCHLORIDE
CAS No.: 62929-91-3
Chemical Name: PROCATEROL HYDROCHLORIDE
Synonyms: meptin;opc2009;Epcalol;Cateptin;Astoprotin;Carvedilol-d;PROCATEROL HCL;Einecs 263-763-0;Aficamten Impurity 26;Procaterol hydrochlorid
CBNumber: CB4120391
Molecular Formula: C16H23ClN2O3
Formula Weight: 326.82
MOL File: 62929-91-3.mol

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PROCATEROL HYDROCHLORIDE Property

storage temp.: 2-8°C
solubility: Soluble to 100 mM in water and to 100 mM in DMSO
form: Powder
color: White to off-white
Stability:: Hygroscopic

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Safety

WGK Germany: 2
RTECS: VC8296000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P9180
Product name: Procaterol hydrochloride
Packaging: 10mg
Price: $185
Updated: 2025/07/31

Cayman Chemical

Product number: 28479
Product name: Procaterol (hydrochloride)
Packaging: 10mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 28479
Product name: Procaterol (hydrochloride)
Packaging: 50mg
Price: $469
Updated: 2024/03/01

Cayman Chemical

Product number: 28479
Product name: Procaterol (hydrochloride)
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 28479
Product name: Procaterol (hydrochloride)
Packaging: 25mg
Price: $252
Updated: 2024/03/01

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PROCATEROL HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Procaterol is an agonist of β₂-adrenergic receptors (β₂-ARs). It binds to (K_d = 46 pM), and is selective for, β₂-ARs over β₁-ARs (K_d = 4,000 pM). Procaterol binds more potently to β₂-ARs in isolated guinea pig lung than to β₁-ARs in isolated guinea pig cardiac ventricle in the presence (IC_50s = 175 and 1,660 nM, respectively) and absence of GTP (; IC₅₀s = 55.1 and 1,660 nM, respectively). It inhibits contractions induced by acetylcholine in isolated guinea pig trachea (EC₅₀ = 10.5 nM). In vivo, procaterol inhibits histamine-induced airflow obstruction in a guinea pig model of ovalbumin-sensitized asthma when administered via inhalation at a dose of 10 μg/ml.

Uses

adrenergic agonists

Uses

Procaterol Hydrochloride is a short-acting pulmonary β2-agonist for asthma treatment.

General Description

Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.

Biological Activity

Specific and very potent β 2 agonist.

Biochem/physiol Actions

β2-adrenoceptor agonist; bronchodilator.

storage

Store at RT

References

[1] S MARULLO. Selective binding of ligands to beta 1, beta 2 or chimeric beta 1/beta 2-adrenergic receptors involves multiple subsites.[J]. EMBO Journal, 1990, 9 5: 1471-1476. DOI: 10.1002/j.1460-2075.1990.tb08264.x
[2] HIDEO KIKKAWA Katsuo I Kazuaki Naito. Tracheal Relaxing Effects and β2-Selectivity of TA-2005, a Newly Developed Bronchodilating Agent, in Isolated Guinea Pig Tissues[J]. Japanese journal of pharmacology, 1991, 57 2: Pages 175-185. DOI: 10.1254/jjp.57.175
[3] SHIRO YOSHIZAKI. Sympathomimetic amines having a carbostyril nucleus[J]. Journal of Medicinal Chemistry, 1976, 19 9: 1138-1142. DOI: 10.1021/jm00231a011
[4] MIRZA. Inhaled procaterol inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammation[J]. Clinical and Experimental Allergy, 2008, 28 5: 644-652. DOI: 10.1046/j.1365-2222.1998.00263.x

PROCATEROL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PROCATEROL HYDROCHLORIDE manufacturers

Dideu Industries Group Limited

Product: PROCATEROL HYDROCHLORIDE 62929-91-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-05-28

Career Henan Chemical Co

Product: PROCATEROL HYDROCHLORIDE 62929-91-3
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

62929-91-3, PROCATEROL HYDROCHLORIDERelated Search:

5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol Ketotifen fumarate 2-(ISO-PROPYLAMINO)ETHYLSTYRENE PROCATEROL HYDROCHLORIDE (R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone 2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE 2-(1-Aminoethyl)-4-hydroxybenzyl alcohol hydrochloride

Procaterol hydrochlorid

erythro-8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1h)-quinolinone

2(1H)-Quinolinone, 8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, rel- (9CI)

Procaterol HCl,Procaterol hydrochloride

8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one hydrate hydrochloride

2(1H)-Quinolinone, 8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, (R*,S*)-

2(1H)-Quinolinone, 8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, (R*,S*)-(+-)-

PROCATEROL HCL

5-(1-hydroxy-2-isopropylamino)butyl-8-hydroxycarbostyrilhydrochloride

8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1h)-quinolinonmono

meptin

opc2009

(R*,S*)-(±)-8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]quinolin-2(1H)-one monohydrochloride

Astoprotin

Cateptin

Epcalol

(R*,S*)-(1)-8-Hydroxy-5-(1-hydroxy-2-(isopropylamino)butyl)quinolin-2(1H)-one monohydrochloride

Einecs 263-763-0

rel-8-Hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-2(1H)quinolinone hydrochloride

(+/-)-ERYTHRO-8-HYDROXY-5-[1-HYDROXY-2-(ISOPROPYLAMINO)BUTYL]CARBOSTYRIL HYDROCHLORIDE

8-HYDROXY-5-(1-HYDROXY-2-PROPAN-2-YLAMINO-BUTYL)-1H-QUINOLIN-2-ONE

Procaterol hydrochloride Solution, 100ppm

Procaterol hydrochloride Solution, 1000ppm

Carvedilol-d

Aficamten Impurity 26

Procaterol hydrochloride, beta2 adrenoceptor agonist

62929-91-3

C16H22N2O3HClH2O

Adrenoceptor