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PROCATEROL HYDROCHLORIDE

Product Name
PROCATEROL HYDROCHLORIDE
CAS No.
62929-91-3
Chemical Name
PROCATEROL HYDROCHLORIDE
Synonyms
meptin;opc2009;Epcalol;Cateptin;Astoprotin;Carvedilol-d;PROCATEROL HCL;Einecs 263-763-0;Aficamten Impurity 26;Procaterol hydrochlorid
CBNumber
CB4120391
Molecular Formula
C16H23ClN2O3
Formula Weight
326.82
MOL File
62929-91-3.mol
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PROCATEROL HYDROCHLORIDE Property

storage temp. 
2-8°C
solubility 
Soluble to 100 mM in water and to 100 mM in DMSO
form 
Powder
color 
White to off-white
Stability:
Hygroscopic
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Safety

WGK Germany 
2
RTECS 
VC8296000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P9180
Product name
Procaterol hydrochloride
Packaging
10mg
Price
$185
Updated
2025/07/31
Cayman Chemical
Product number
28479
Product name
Procaterol (hydrochloride)
Packaging
10mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
28479
Product name
Procaterol (hydrochloride)
Packaging
50mg
Price
$469
Updated
2024/03/01
Cayman Chemical
Product number
28479
Product name
Procaterol (hydrochloride)
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
28479
Product name
Procaterol (hydrochloride)
Packaging
25mg
Price
$252
Updated
2024/03/01
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PROCATEROL HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Procaterol is an agonist of β2-adrenergic receptors (β2-ARs). It binds to (Kd = 46 pM), and is selective for, β2-ARs over β1-ARs (Kd = 4,000 pM). Procaterol binds more potently to β2-ARs in isolated guinea pig lung than to β1-ARs in isolated guinea pig cardiac ventricle in the presence (IC50s = 175 and 1,660 nM, respectively) and absence of GTP (; IC50s = 55.1 and 1,660 nM, respectively). It inhibits contractions induced by acetylcholine in isolated guinea pig trachea (EC50 = 10.5 nM). In vivo, procaterol inhibits histamine-induced airflow obstruction in a guinea pig model of ovalbumin-sensitized asthma when administered via inhalation at a dose of 10 μg/ml.

Uses

adrenergic agonists

Uses

Procaterol Hydrochloride is a short-acting pulmonary β2-agonist for asthma treatment.

General Description

Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.

Biological Activity

Specific and very potent β 2 agonist.

Biochem/physiol Actions

β2-adrenoceptor agonist; bronchodilator.

storage

Store at RT

References

[1] S MARULLO. Selective binding of ligands to beta 1, beta 2 or chimeric beta 1/beta 2-adrenergic receptors involves multiple subsites.[J]. EMBO Journal, 1990, 9 5: 1471-1476. DOI: 10.1002/j.1460-2075.1990.tb08264.x
[2] HIDEO KIKKAWA  Katsuo I  Kazuaki Naito. Tracheal Relaxing Effects and β2-Selectivity of TA-2005, a Newly Developed Bronchodilating Agent, in Isolated Guinea Pig Tissues[J]. Japanese journal of pharmacology, 1991, 57 2: Pages 175-185. DOI: 10.1254/jjp.57.175
[3] SHIRO YOSHIZAKI. Sympathomimetic amines having a carbostyril nucleus[J]. Journal of Medicinal Chemistry, 1976, 19 9: 1138-1142. DOI: 10.1021/jm00231a011
[4] MIRZA. Inhaled procaterol inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammation[J]. Clinical and Experimental Allergy, 2008, 28 5: 644-652. DOI: 10.1046/j.1365-2222.1998.00263.x

PROCATEROL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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PROCATEROL HYDROCHLORIDE Suppliers

Canada 1 China 61 Germany 2 India 1 Switzerland 1 United Kingdom 6 United States 18 Global 90
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from PROCATEROL HYDROCHLORIDE manufacturers

Dideu Industries Group Limited
Product
PROCATEROL HYDROCHLORIDE 62929-91-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-05-28
Career Henan Chemical Co
Product
PROCATEROL HYDROCHLORIDE 62929-91-3
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

62929-91-3, PROCATEROL HYDROCHLORIDERelated Search:

5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol Ketotifen fumarate 2-(ISO-PROPYLAMINO)ETHYLSTYRENE PROCATEROL HYDROCHLORIDE (R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone 2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE 2-(1-Aminoethyl)-4-hydroxybenzyl alcohol hydrochloride

  • Procaterol hydrochlorid
  • erythro-8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1h)-quinolinone
  • 2(1H)-Quinolinone, 8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, rel- (9CI)
  • Procaterol HCl,Procaterol hydrochloride
  • 8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one hydrate hydrochloride
  • 2(1H)-Quinolinone, 8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, (R*,S*)-
  • 2(1H)-Quinolinone, 8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, (R*,S*)-(+-)-
  • PROCATEROL HCL
  • 5-(1-hydroxy-2-isopropylamino)butyl-8-hydroxycarbostyrilhydrochloride
  • 8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1h)-quinolinonmono
  • meptin
  • opc2009
  • (R*,S*)-(±)-8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]quinolin-2(1H)-one monohydrochloride
  • Astoprotin
  • Cateptin
  • Epcalol
  • (R*,S*)-(1)-8-Hydroxy-5-(1-hydroxy-2-(isopropylamino)butyl)quinolin-2(1H)-one monohydrochloride
  • Einecs 263-763-0
  • rel-8-Hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-2(1H)quinolinone hydrochloride
  • (+/-)-ERYTHRO-8-HYDROXY-5-[1-HYDROXY-2-(ISOPROPYLAMINO)BUTYL]CARBOSTYRIL HYDROCHLORIDE
  • 8-HYDROXY-5-(1-HYDROXY-2-PROPAN-2-YLAMINO-BUTYL)-1H-QUINOLIN-2-ONE
  • Procaterol hydrochloride Solution, 100ppm
  • Procaterol hydrochloride Solution, 1000ppm
  • Carvedilol-d
  • Aficamten Impurity 26
  • Procaterol hydrochloride, beta2 adrenoceptor agonist
  • 62929-91-3
  • C16H22N2O3HClH2O
  • Adrenoceptor