(9S)-9-Amino-9-deoxoerythromycin

Product Name: (9S)-9-Amino-9-deoxoerythromycin
CAS No.: 26116-56-3
Chemical Name: (9S)-9-Amino-9-deoxoerythromycin
Synonyms: LY 024410;Brn 4241492;BRL 42852ER;Erythromycylamine;Erythromycilamine;9-Epierythromycylamine;Epierythromycyl-A-amine;9-(S)-AMINOERYTHROMYCIN;(9S)-erythromycyclamine;(9S)-Erythromycylamine A
CBNumber: CB41236921
Molecular Formula: C37H70N2O12
Formula Weight: 734.96
MOL File: 26116-56-3.mol

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(9S)-9-Amino-9-deoxoerythromycin Property

Melting point:: 123-127°C
Boiling point:: 810.3±65.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
form: A solid
pka: 13.41±0.70(Predicted)

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Safety

Hazard Codes: Xi,N
Risk Statements: 41-50/53
Safety Statements: 26-39-60-61
Toxicity: mouse,LD50,intraperitoneal,120mg/kg (120mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 83, 1978.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28098
Product name: Erythromycylamine
Packaging: 1mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 28098
Product name: Erythromycylamine
Packaging: 10mg
Price: $903
Updated: 2024/03/01

Cayman Chemical

Product number: 28098
Product name: Erythromycylamine
Packaging: 5mg
Price: $481
Updated: 2024/03/01

Usbiological

Product number: 257299
Product name: Erythromycylamine
Packaging: 1mg
Price: $531
Updated: 2021/12/16

TRC

Product number: E653400
Product name: Erythromycylamine
Packaging: 10mg
Price: $1070
Updated: 2021/12/16

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(9S)-9-Amino-9-deoxoerythromycin Chemical Properties,Usage,Production

Chemical Properties

(9S)-9-Amino-9-deoxoerythromycin is White Solid

Uses

(9S)-9-Amino-9-deoxoerythromycin is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. (9S)-9-Amino-9-deoxoerythromycin is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

Uses

Erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. Erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

Uses

(9S)-9-Amino-9-deoxoerythromycin is a metabolite of Dirithromycin; an antibiotic

Definition

ChEBI: A macrolide antibiotic that is erythromycin A in which the ketone group has been converted to the corresponding imine and then reduced to give the corresponding amino compound (the 9S diastereoisomer).

(9S)-9-Amino-9-deoxoerythromycin Preparation Products And Raw materials

Raw materials

Preparation Products

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(9S)-9-Amino-9-deoxoerythromycin Suppliers

Canada 1 China 68 India 3 United Kingdom 1 United States 9 Global 82

Heifei Yuanzhi Pharmaceutical R&D Co.,Ltd

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Shanghai Kewel Chemical Co., Ltd.

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View Lastest Price from (9S)-9-Amino-9-deoxoerythromycin manufacturers

Career Henan Chemical Co

Product: (9S)-9-Amino-9-deoxoerythromycin 26116-56-3
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2019-12-25

26116-56-3, (9S)-9-Amino-9-deoxoerythromycinRelated Search:

Cyprodinil Pyrimethanil Dirithromycin impurity N-Demethyl-N-Propanoyl Erythromycin erythronolide B (9S)-9-Amino-9-deoxoerythromycin-d3 (9S)-9-[[[4-(Acetylamino)phenyl]sulfonyl]amino]-9-deoxoerythromycin (9S)-9-[[(4-Chlorophenyl)sulfonyl]amino]-9-deoxoerythromycin (9S)-9-[[(4-Bromophenyl)sulfonyl]amino]-9-deoxoerythromycin Dirithromycin (9S)-9-Amino-9-deoxoerythromycin

(9S)-9-Amino-9-deoxoerythromycin

(9S)-9-amino-9-deoxyerythromycin

9-Amino-9-deoxo-erythromycin, stereoisomer

9-Epierythromycylamine

Brn 4241492

Epierythromycyl-A-amine

Erythromycin, 9-amino-9-deoxo-, (9S)- (9ci)

Erythromycin, 9-amino-9-deoxo-, stereoisomer

(9S)-9-AMiNA-9-deoxoerythroMycin

9-(S)-AMINOERYTHROMYCIN

9-(S)-ERYTHROMYCYLAMINE:9-AMINO-9-DEOXO-ERYTHROMYCIN

(9S)-9-Deoxy-9-aminoerythromycin A

(9S)-Erythromycylamine A

BRL 42852ER

Erythromycylamine

LY 024410

(9s)-9-aMino-9-deoxoeryhtroMycin

9(S) ErythroMycylaMin A, BRL 42852ER, LY 024410

(9S)-erythromycyclamine

Dirithromycin EP impurity A

(9S)-9-Amino-9-deoxoerythromycin (9S)-9-Amino-9-deoxoerythromycin

Dirithromycin impurity A

Dirithromycin Impurity 1(Dirithromycin EP Impurity A)

Dirithromycin EP Impurity A/Erythromycylamine/(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimeth

Dirithromycin Impurit Ⅰ: (9S)-9-Amino-9-deoxoerythromycin

Erythromycilamine

Dirithromycin EP Impurity A (Erythromycylamine)

Erythromycin, 9-amino-9-deoxo-, (9S)-

Erythromycylamine (Dirithromycin EP Impurity A)

Erythromycylamine-13C-d3

(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-Amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

Erythromycylamine-13C-d3 (Dirithromycin EP Impurity A-13C-d3)

erythromyclamine, (9R)-isomer

(9S)-9-Amino-9-deoxoerythromycin (Dirithromycin Impurity)

26116-56-3

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Various Metabolites and Impurities