ChemicalBook > CAS DataBase List > (9S)-9-Amino-9-deoxoerythromycin

(9S)-9-Amino-9-deoxoerythromycin

Product Name
(9S)-9-Amino-9-deoxoerythromycin
CAS No.
26116-56-3
Chemical Name
(9S)-9-Amino-9-deoxoerythromycin
Synonyms
LY 024410;Brn 4241492;BRL 42852ER;Erythromycylamine;Erythromycilamine;9-Epierythromycylamine;Epierythromycyl-A-amine;9-(S)-AMINOERYTHROMYCIN;(9S)-erythromycyclamine;(9S)-Erythromycylamine A
CBNumber
CB41236921
Molecular Formula
C37H70N2O12
Formula Weight
734.96
MOL File
26116-56-3.mol
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(9S)-9-Amino-9-deoxoerythromycin Property

Melting point:
123-127°C
Boiling point:
810.3±65.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
form 
A solid
pka
13.41±0.70(Predicted)
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Safety

Hazard Codes 
Xi,N
Risk Statements 
41-50/53
Safety Statements 
26-39-60-61
Toxicity
mouse,LD50,intraperitoneal,120mg/kg (120mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 83, 1978.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28098
Product name
Erythromycylamine
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
28098
Product name
Erythromycylamine
Packaging
10mg
Price
$903
Updated
2024/03/01
Cayman Chemical
Product number
28098
Product name
Erythromycylamine
Packaging
5mg
Price
$481
Updated
2024/03/01
Usbiological
Product number
257299
Product name
Erythromycylamine
Packaging
1mg
Price
$531
Updated
2021/12/16
TRC
Product number
E653400
Product name
Erythromycylamine
Packaging
10mg
Price
$1070
Updated
2021/12/16
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(9S)-9-Amino-9-deoxoerythromycin Chemical Properties,Usage,Production

Chemical Properties

(9S)-9-Amino-9-deoxoerythromycin is White Solid

Uses

(9S)-9-Amino-9-deoxoerythromycin is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. (9S)-9-Amino-9-deoxoerythromycin is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

Uses

Erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. Erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

Uses

(9S)-9-Amino-9-deoxoerythromycin is a metabolite of Dirithromycin; an antibiotic

Definition

ChEBI: A macrolide antibiotic that is erythromycin A in which the ketone group has been converted to the corresponding imine and then reduced to give the corresponding amino compound (the 9S diastereoisomer).

(9S)-9-Amino-9-deoxoerythromycin Preparation Products And Raw materials

Raw materials

Preparation Products

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(9S)-9-Amino-9-deoxoerythromycin Suppliers

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View Lastest Price from (9S)-9-Amino-9-deoxoerythromycin manufacturers

Career Henan Chemical Co
Product
(9S)-9-Amino-9-deoxoerythromycin 26116-56-3
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

26116-56-3, (9S)-9-Amino-9-deoxoerythromycinRelated Search:

Cyprodinil Pyrimethanil Dirithromycin impurity N-Demethyl-N-Propanoyl Erythromycin erythronolide B (9S)-9-Amino-9-deoxoerythromycin-d3 (9S)-9-[[[4-(Acetylamino)phenyl]sulfonyl]amino]-9-deoxoerythromycin (9S)-9-[[(4-Chlorophenyl)sulfonyl]amino]-9-deoxoerythromycin (9S)-9-[[(4-Bromophenyl)sulfonyl]amino]-9-deoxoerythromycin Dirithromycin (9S)-9-Amino-9-deoxoerythromycin

  • (9S)-9-Amino-9-deoxoerythromycin
  • (9S)-9-amino-9-deoxyerythromycin
  • 9-Amino-9-deoxo-erythromycin, stereoisomer
  • 9-Epierythromycylamine
  • Brn 4241492
  • Epierythromycyl-A-amine
  • Erythromycin, 9-amino-9-deoxo-, (9S)- (9ci)
  • Erythromycin, 9-amino-9-deoxo-, stereoisomer
  • (9S)-9-AMiNA-9-deoxoerythroMycin
  • 9-(S)-AMINOERYTHROMYCIN
  • 9-(S)-ERYTHROMYCYLAMINE:9-AMINO-9-DEOXO-ERYTHROMYCIN
  • (9S)-9-Deoxy-9-aminoerythromycin A
  • (9S)-Erythromycylamine A
  • BRL 42852ER
  • Erythromycylamine
  • LY 024410
  • (9s)-9-aMino-9-deoxoeryhtroMycin
  • 9(S) ErythroMycylaMin A, BRL 42852ER, LY 024410
  • (9S)-erythromycyclamine
  • Dirithromycin EP impurity A
  • (9S)-9-Amino-9-deoxoerythromycin (9S)-9-Amino-9-deoxoerythromycin
  • Dirithromycin impurity A
  • Dirithromycin Impurity 1(Dirithromycin EP Impurity A)
  • Dirithromycin EP Impurity A/Erythromycylamine/(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimeth
  • Dirithromycin Impurit Ⅰ: (9S)-9-Amino-9-deoxoerythromycin
  • Erythromycilamine
  • Dirithromycin EP Impurity A (Erythromycylamine)
  • Erythromycin, 9-amino-9-deoxo-, (9S)-
  • Erythromycylamine (Dirithromycin EP Impurity A)
  • Erythromycylamine-13C-d3
  • (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-Amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
  • Erythromycylamine-13C-d3 (Dirithromycin EP Impurity A-13C-d3)
  • erythromyclamine, (9R)-isomer
  • (9S)-9-Amino-9-deoxoerythromycin (Dirithromycin Impurity)
  • 26116-56-3
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Various Metabolites and Impurities