3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE
- Product Name
- 3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE
- CAS No.
- 86156-93-6
- Chemical Name
- 3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE
- Synonyms
- 3-Fluoro-4-nitrobenzenesulfony;3-fluoro-4-nitrophenylsulfonyl chloride;3-Fluro-4-nitro-benzensulfonyl chloride;3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE;3-Fluoro-4-nitrobenzenesulphonyl chloride;Benzenesulfonyl chloride, 3-fluoro-4-nitro-;3-fluoro-4-nitrobenzene-1-sulfonyl chloride;Benzenesulfonyl chloride, 3-fluoro-4-nitro- (9CI)
- CBNumber
- CB4125396
- Molecular Formula
- C6H3ClFNO4S
- Formula Weight
- 239.61
- MOL File
- 86156-93-6.mol
3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE Property
- Melting point:
- 45-48°C
- Boiling point:
- 126°C/0.25mm
- Density
- 1.685±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- color
- Light yellow
- Sensitive
- Moisture Sensitive
Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- 3261
- HazardClass
- IRRITANT, CORROSIVE
- HazardClass
- 8
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P309IF exposed or if you feel unwell:
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 8662-7-09
- Product name
- 3-Fluoro-4-nitrobenzenesulfonyl chloride
- Packaging
- 1g
- Price
- $53
- Updated
- 2021/12/16
- Product number
- 044111
- Product name
- 3-Fluoro-4-nitrobenzenesulfonyl chloride
- Packaging
- 250mg
- Price
- $29
- Updated
- 2021/12/16
- Product number
- 044111
- Product name
- 3-Fluoro-4-nitrobenzenesulfonyl chloride
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
- Product number
- PC500352
- Product name
- 3-Fluoro-4-nitrobenzenesulphonylchloride
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
- Product number
- 024659
- Product name
- 3-Fluoro-4-nitrobenzenesulfonyl chloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $49
- Updated
- 2021/12/16
3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE Chemical Properties,Usage,Production
Synthesis
2369-13-3
86156-93-6
The general procedure for the synthesis of 3-fluoro-4-nitrobenzenesulfonyl chloride from 3-fluoro-4-nitroaniline is as follows: 3-fluoro-4-nitroaniline (15 g, 96.1 mmol, Combi Blocks) was dissolved in hydrochloric acid (120 ml) at 0°C, and sodium nitrite dissolved in water (10 ml) was slowly added (7.9 g, 115.0 mmol Qualigens). The reaction temperature was maintained at 0°C and the mixture was stirred for 30 min. Subsequently, the resulting diazonium salt solution was added dropwise to a pre-cooled solution of copper(II) chloride dihydrate (14.4 g, 96.1 mmol, Aldrich) in acetic acid (80 ml), while sulfur dioxide gas was passed to saturation. The reaction mixture was continued to be stirred at 25°C for 1 hour. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was poured into ice-cold water and the solid product was precipitated. The solid was collected by filtration, washed with water and dried in air to afford 14.2 g of 3-fluoro-4-nitrobenzenesulfonyl chloride as a brown solid in 62% yield. The structure of the product was confirmed by 1H-NMR (400 MHz, DMSO): δ 8.29 (t, J = 7.2 Hz, 1H), 8.01 (dd, 2H).
References
[1] Patent: WO2013/122897, 2013, A1. Location in patent: Page/Page column 175; 176
[2] Helvetica Chimica Acta, 1983, vol. 66, # 1, p. 68 - 75
[3] Patent: WO2003/76413, 2003, A1. Location in patent: Page/Page column 28-30
[4] Patent: WO2017/156181, 2017, A1. Location in patent: Paragraph 00359
3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE Suppliers
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- info@chemstep.com
- Country
- Europe
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- Advantage
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View Lastest Price from 3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE manufacturers
- Product
- 6-Chloro-5-nitropyridine-2-carboxylic acid 353277-27-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-09
- Product
- 3-FLUORO-4-NITROBENZENESULFONYL CHLORIDE 86156-93-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-09