ChemicalBook > CAS DataBase List > 6-Benzothiazolol(7CI,8CI,9CI)

6-Benzothiazolol(7CI,8CI,9CI)

Product Name
6-Benzothiazolol(7CI,8CI,9CI)
CAS No.
13599-84-3
Chemical Name
6-Benzothiazolol(7CI,8CI,9CI)
Synonyms
6-Benzothiazolol;6-Hydroxybenzothiazol;6-hydroxybenzothiazole;6-Hydroxybenzothiazole>6-Benzothiazolol(7CI,8CI,9CI)
CBNumber
CB41273003
Molecular Formula
C7H5NOS
Formula Weight
151.19
MOL File
13599-84-3.mol
More
Less

6-Benzothiazolol(7CI,8CI,9CI) Property

Melting point:
185.0 to 189.0 °C
Boiling point:
311.6±15.0 °C(Predicted)
Density 
1.444±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
8.52±0.40(Predicted)
color 
White to Light yellow
More
Less

Safety

HS Code 
2934100090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
H1380
Product name
6-Hydroxybenzothiazole
Purity
>96.0%(GC)
Packaging
1g
Price
$427
Updated
2025/07/31
TCI Chemical
Product number
H1380
Product name
6-Hydroxybenzothiazole
Purity
>96.0%(GC)
Packaging
5g
Price
$1290
Updated
2025/07/31
TRC
Product number
B443803
Product name
6-Hydroxybenzothiazole
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
072194
Product name
6-Hydroxybenzothiazole
Purity
95+%
Packaging
1g
Price
$30
Updated
2021/12/16
Matrix Scientific
Product number
072194
Product name
6-Hydroxybenzothiazole
Purity
95+%
Packaging
5g
Price
$94
Updated
2021/12/16
More
Less

6-Benzothiazolol(7CI,8CI,9CI) Chemical Properties,Usage,Production

Uses

6-Hydroxybenzothiazole is a useful research chemical used in the synthesis of aryl trifluoromethyl ethers.

Synthesis

129058-50-0

13599-84-3

6-Hydroxybenzothiazole was synthesized using 2-cyano-6-methoxybenzothiazole as starting material after the following steps: first, the ethyl acetate extract was washed with 1 M NaOH solution (50 mL), followed by acidification of the aqueous phase with 3 M HCl and extraction with ethyl acetate. The extract was evaporated from the solvent at 60 °C to induce complete decarboxylation of the unstable acid 13b. Purification of the product by column chromatography (eluent ratio dichloromethane/acetone 95:5) afforded 6-hydroxybenzothiazole 14 as a colorless solid. Further purification by recrystallization from aqueous ethanol gave 0.7 g (4.6 mmol, 50% yield) of the target product. The melting point of the compound was 190-192 °C (literature value 24: 184-185 °C), and the Rf value for thin layer chromatography was 0.35 (unfolding agent ratio petroleum ether/ethyl acetate 6:4).1H NMR (CD3OD) data were as follows: δ = 8.98 (s, 1H, 2-H), 7.88 (d, J = 8.3 Hz, 1H, 4-H), 7.38 (d, J = 2.1 Hz, 1H, 7-H), 7.06 (dd, J = 8.3 and 2.1 Hz, 1H, 5-H) ppm. 13C NMR (CD3OD) data were as follows: δ = 164.8 (6-C), 155.9 (9-C), 152.1 (2-CH), 134.9 (8-C), 122.8 (4-CH), 115.9 (5 -CH), 106.1 (7-CH) ppm.

References

[1] Synthesis, 2001, # 12, p. 1780 - 1783
[2] Tetrahedron, 2013, vol. 69, # 29, p. 5893 - 5897

6-Benzothiazolol(7CI,8CI,9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6-Benzothiazolol(7CI,8CI,9CI) Suppliers

R&D Scientific Inc.
Tel
+1-2266000236
Email
sales@rdscientific.com
Country
Canada
ProdList
1902
Advantage
58
More
Less

View Lastest Price from 6-Benzothiazolol(7CI,8CI,9CI) manufacturers

R&D Scientific Inc.
Product
6-Hydroxybenzothiazole 13599-84-3
Price
US $790.00/g
Min. Order
1g
Purity
98
Supply Ability
5000 Kg
Release date
2025-04-07
Henan Aochuang Chemical Co.,Ltd.
Product
6-Benzothiazolol(7CI,8CI,9CI) 13599-84-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-18
Honest Joy Holdings Limited
Product
6-Hydroxybenzothiazole, 13599-84-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
100 tons
Release date
2022-01-26