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Pinealon

Product Name
Pinealon
CAS No.
175175-23-2
Chemical Name
Pinealon
Synonyms
Pinealon;Peptides Lyophilized;Peptides Lyophilized Powder;L-Arginine, L-α-glutamyl-L-α-aspartyl-
CBNumber
CB412960538
Molecular Formula
C15H26N6O8
Formula Weight
418.4
MOL File
175175-23-2.mol
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Pinealon Property

Density 
1.63±0.1 g/cm3(Predicted)
pka
3.15±0.10(Predicted)
Sequence
H-Glu-Asp-Arg-OH
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Hazard and Precautionary Statements (GHS)

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Pinealon Chemical Properties,Usage,Production

Description

Pinealon is a 3-amino acid peptide and shows neuroprotective properties. Pinealon prevents reactive oxygen species (ROS) accumulation and suppresses the activation of ERK 1/2. Pinealon stimulates the functional activity of the main cellular elements of brain tissue, reduces the level of spontaneous cell death. Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.

benefits

EDR (Glu-Asp-Arg, Pinealon), a tripeptide isolated from the polypeptide neuroprotective drug Cortexin, is one of the neuroprotective arginine-containing peptides. Oral administration of Pinealon revealed its effectiveness in correcting cerebral dysfunctions in older age groups. The EDR peptide contributed to neuronal apoptosis reduction, improvement of memory, attention and cognitive functions, acceleration of perceptual-motor responses, an increased mental performance, and decreased central nervous system (CNS) ageing in the elderly[1].

in vitro

Pinealon (10, 50, 100 nM; 30 min) in a dose-dependent manner prevents an increase in the ROS accumulation induced by ouabain in cerebellar granule cells.
Pinealon (10 nM; 0, 2.5, 5, 10, 20, 30 min) suppresses the activation of ERK 1/2 in rat cerebellar granule cells exposed to 500 mM homo-cysteine (HC).

References

[1] Vladimir Khavinson. “EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer’s Disease.” Molecules (2020).

Pinealon Preparation Products And Raw materials

Raw materials

Preparation Products

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Pinealon Suppliers

Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q3252066219
Fax
QQ3382968513
Email
danping@shsendpharm.com
Country
China
ProdList
3100
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-025-58361106-805-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9980
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4810
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
6958
Advantage
58
Shanghai Longyu Biotechnology Co., Ltd.
Tel
+8619521488211
Fax
+86 15821988213
Email
info@longyupharma.com
Country
China
ProdList
2558
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-88211921 15572296305
Email
sales4@gotopbio.com
Country
China
ProdList
5178
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6628
Advantage
58
Taiyuan Bailihengkang Biotechnology Co., Ltd
Tel
19135651983 19135651983
Email
18611134419@163.com
Country
China
ProdList
4416
Advantage
58
Jiangsu Chunhui Medical Technology Co., Ltd
Tel
13913819195
Email
3851343186@qq.com
Country
China
ProdList
133
Advantage
58
Changsha MOL Changes Biotechnology Co., Ltd.
Tel
+8619375158599
Email
info@molchanges.com
Country
China
ProdList
5223
Advantage
58
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View Lastest Price from Pinealon manufacturers

Dorne Chemical Technology co. LTD
Product
Pinealon 175175-23-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Shanghai Affida new material science and technology center
Product
Pinealon 175175-23-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99
Supply Ability
10 tons
Release date
2024-03-20
Hebei Weimiao Import and Export Trade Co., Ltd.
Product
pinealon 175175-23-2
Price
US $156.00-152.00/Box
Min. Order
1Box
Purity
99%
Supply Ability
66666
Release date
2023-12-19

175175-23-2, Pinealon Related Search:


  • L-Arginine, L-α-glutamyl-L-α-aspartyl-
  • Peptides Lyophilized
  • Peptides Lyophilized Powder
  • Pinealon
  • 175175-23-2