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marcfortine A

Product Name
marcfortine A
CAS No.
75731-43-0
Chemical Name
marcfortine A
Synonyms
UK 111866;marcfortine A;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)-
CBNumber
CB41323193
Molecular Formula
C28H35N3O4
Formula Weight
477.602
MOL File
75731-43-0.mol
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marcfortine A Property

Melting point:
245 °C
Boiling point:
660.6±55.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Methanol: soluble
form 
A solid
pka
12.05±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23486
Product name
Marcfortine A
Purity
≥99%
Packaging
1mg
Price
$340
Updated
2024/03/01
Cayman Chemical
Product number
23486
Product name
Marcfortine A
Purity
≥99%
Packaging
5mg
Price
$1523
Updated
2024/03/01
Usbiological
Product number
M2374-75
Product name
Marcfortine A
Packaging
1mg
Price
$588
Updated
2021/12/16
TRC
Product number
M197305
Product name
MarcfortineA
Packaging
2.5mg
Price
$625
Updated
2021/12/16
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marcfortine A Chemical Properties,Usage,Production

Description

Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.

Uses

Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission.

Uses

Marcfortine A is an indole alkaloid isolated from Aspergillus and Pencillium species.

marcfortine A Preparation Products And Raw materials

Raw materials

Preparation Products

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marcfortine A Suppliers

China 12 United Kingdom 1 United States 5 Global 18
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58

75731-43-0, marcfortine ARelated Search:

C-[1-(4-METHOXY-PHENYL)-CYCLOPENTYL]-METHYLAMINE N-CYCLOPENTYL-N-METHYL-2-PIPERIDINEMETHANAMINE 2H-Indol-2-one,1,3-dihydro-6,7-dihydroxy-(9CI) ALPHA-PROPYLDOPACETAMIDE 1,1-DIMETHYL-2-PIPERIDIN-1-YL-ETHYLAMINE CHEMBRDG-BB 4017497 CHEMBRDG-BB 4011370 [1-(3,4-DIMETHOXYPHENYL)CYCLOPENTYL]METHANAMINE CHEMBRDG-BB 4011371 2,5-Diazabicyclo[2.2.2]octane 2H-Pyrido[1,2-a]pyrazin-1(6H)-one,hexahydro-(6CI,8CI,9CI) (1S,4S)-2,5-DIAZABICYCLO(2.2.2)OCTANE marcfortine A

  • marcfortine A
  • UK 111866
  • Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)-
  • 75731-43-0