1,3-Bis(diphenylphosphino)propane

Product Name: 1,3-Bis(diphenylphosphino)propane
CAS No.: 6737-42-4
Chemical Name: 1,3-Bis(diphenylphosphino)propane
Synonyms: DPPP;1,3-bis(diphenyphosphino)propane;Bis(1,3-diphenylphosphino)propane;1,3-BIS(DIPHENYLPHOSPHINE)PROPANE;98% DPPP;1,3-Bis(diphenyL;phosphino)propane;PH2PCH2 CH2CH2PPH2;1,3-BIS(DIPHENYPHOSPHINO);1,3-bis-(diphosphino)propane
CBNumber: CB4132404
Molecular Formula: C27H26P2
Formula Weight: 412.45
MOL File: 6737-42-4.mol

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1,3-Bis(diphenylphosphino)propane Property

Melting point:: 63-65 °C (lit.)
Boiling point:: 529.7±33.0 °C(Predicted)
Flash point:: 235°C
storage temp.: Inert atmosphere,Room Temperature
form: Granules or Powder
color: White to light yellow-beige
Water Solubility: insoluble
Sensitive: Air Sensitive
BRN: 2821785
InChI: InChI=1S/C27H26P2/c1-5-14-24(15-6-1)28(25-16-7-2-8-17-25)22-13-23-29(26-18-9-3-10-19-26)27-20-11-4-12-21-27/h1-12,14-21H,13,22-23H2
InChIKey: LVEYOSJUKRVCCF-UHFFFAOYSA-N
SMILES: P(C1C=CC=CC=1)(C1C=CC=CC=1)CCCP(C1C=CC=CC=1)C1C=CC=CC=1
CAS DataBase Reference: 6737-42-4(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Bis(diphenylphosphino)propane(6737-42-4)
EPA Substance Registry System: Phosphine, 1,3-propanediylbis[diphenyl- (6737-42-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36
WGK Germany: 3
F: 10-23
TSCA: Yes
HS Code: 29310095

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 262048
Product name: 1,3-Bis(diphenylphosphino)propane
Purity: 97%
Packaging: 1g
Price: $36.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: 262048
Product name: 1,3-Bis(diphenylphosphino)propane
Purity: 97%
Packaging: 5g
Price: $67.3
Updated: 2025/07/31

TCI Chemical

Product number: B1138
Product name: 1,3-Bis(diphenylphosphino)propane
Purity: >98.0%(GC)
Packaging: 5g
Price: $26
Updated: 2025/07/31

TCI Chemical

Product number: B1138
Product name: 1,3-Bis(diphenylphosphino)propane
Purity: >98.0%(GC)
Packaging: 25g
Price: $60
Updated: 2025/07/31

Strem Chemicals

Product number: 15-0450
Product name: 1,3-Bis(diphenylphosphino)propane, 98% DPPP
Packaging: 10g
Price: $87
Updated: 2024/03/01

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1,3-Bis(diphenylphosphino)propane Chemical Properties,Usage,Production

Description

1,3-Bis(diphenylphosphino)propane is a ligand for metal-catalyzed substitution reactions of aryl and vinyl triflates, halides, and carbonates; carbonylation reactions; Grignard coupling; diene alkylation; macrocycle synthesis.

Chemical Properties

white to light yellow crystal powde

Uses

1,3-Bis(diphenylphosphino)propane is used as a bidentate ligand in coordination chemistry and form complex dichloro(1,3-bis(diphenylphosphino)propane)nickel by reacting with nickel(II) chloride. This complex is used as a catalyst for Kumada coupling reaction. It also acts as a ligand for palladium(II) catalysts which is useful for the co-polymerization of carbon monoxide and ethylene to get polyketones. Further, it is employed in palladium-catalyzed arylation under Heck reaction and Suzuki reaction. In addition to this, it serves as a catalyst for Negishi coupling and Sonogashira coupling reactions.

reaction suitability

reagent type: ligand
reaction type: C-C Bond Formation
reagent type: ligand
reaction type: Carbonylations
reagent type: ligand
reaction type: Negishi Coupling
reagent type: ligand
reaction type: Sonogashira Coupling
reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

Synthesis

16524-41-7

6737-42-4

GENERAL METHODS: In a sealed tube, the phosphine oxide derivative (5 mmol) was dissolved in anhydrous toluene (1 M), followed by the addition of InBr3 (1 mol%, 0.05 mmol) and TMDS (1.5 equiv, 7.5 mmol). Depending on the substrate, the reaction mixture was stirred at 100 °C for 7 to 40 h (the progress of the reaction was monitored by 31P NMR). Once the reaction was complete, toluene was removed by evaporation and the product was purified by rapid chromatography on silica gel, using pure cyclohexane as eluent, to give the final target product 1,3-bis(diphenylphosphino)propane.

References

[1] Organometallics, 2014, vol. 33, # 21, p. 6171 - 6178
[2] Synlett, 2007, # 10, p. 1545 - 1548
[3] Journal of the American Chemical Society, 2012, vol. 134, # 44, p. 18325 - 18329
[4] Tetrahedron, 2012, vol. 68, # 15, p. 3151 - 3155
[5] Advanced Synthesis and Catalysis, 2016, vol. 358, # 1, p. 26 - 29

1,3-Bis(diphenylphosphino)propane Preparation Products And Raw materials

Raw materials

Diphenylphosphine Ethanol 1,3-Dichloropropane Acetone Sodium 1,3-Dibromopropane Tetrahydrofuran Ethyl acetate Hydrochloric acid Dichloromethane Sodium hydroxide Triphenylphosphine Magnesium sulfate Lithium n-Butyllithium

Preparation Products

3-DODECYLTHIOPHENE [1,3-Bis(diphenylphosphino)propane]nickel(II) chloride

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1,3-Bis(diphenylphosphino)propane Suppliers

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View Lastest Price from 1,3-Bis(diphenylphosphino)propane manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1,3-Bis(diphenylphosphino)propane 6737-42-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-06

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,3-Bis(diphenylphosphino)propane 6737-42-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

Henan Aochuang Chemical Co.,Ltd.

Product: 1,3-Bis(diphenylphosphino)propane 6737-42-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-18

6737-42-4, 1,3-Bis(diphenylphosphino)propaneRelated Search:

BIS-Tris Propane Di(trimethylol propane) Diphenylmethane tert-Butylchlorodiphenylsilane N-(Carboxymethyl)-N-(phosphonomethyl)-glycine Diphenylsilane Chlorodiphenylphosphine Diphenylphosphine 1,1'-Bis(diphenylphosphino)ferrocene 1,2-Bis(diphenylphosphino)ethane 1,4-Bis(diphenylphosphino)butane Propane DICHLORO[1,3-BIS(DIPHENYLPHOSPHINO)PROPANE]PALLADIUM(II) (2R,4R)-(+)-2,4-BIS(DIPHENYLPHOSPHINO)PENTANE (2S,4S)-(-)-2,4-BIS(DIPHENYLPHOSPHINO)PENTANE [1,3-Bis(diphenylphosphino)propane]nickel(II) chloride 1,1,1-TRIS(DIPHENYLPHOSPHINOMETHYL)ETHANE TRIMETHYLENEBIS(TRIPHENYLPHOSPHONIUM BROMIDE)

1,3-BIS(DIPHENYLPHOSPHINE)PROPANE

1,3-BIS(DIPHENYLPHOSPHINO)PROPANE

DPPP

TRIMETHYLENEBIS(DIPHENYLPHOSPHINE)

[3-(Diphenylphosphino)propyl](diphenyl)phosphine

1,3-Propanediylbis(diphenylphosphine)

Bis(1,3-diphenylphosphino)propane

Phosphine, 1,3-propanediylbis[diphenyl-

Phosphine, trimethylenebis(diphenyl-

Propane-1,3-diylbis(diphenylphosphine)

PROPYLENEBIS(DIPHENYLPHOSPHINE)

1,3-bis(diphenyphosphino)propane

1,3-bis(diphenyphosphino)propane(dppp)

1,3-Bis(Diphenlphosphino)Propane

1,3-Bis(diphenylphosphino)propane,98%DPPP

DPPP/ 1,3-BIS(DIPHENYLPHOSPHINE)PROPANE

DPPP/1,3-BIS- (DIPHENYLPHOSPHINO)PROPANE

PH2PCH2 CH2CH2PPH2

1,3-propanediylbis[diphenyl-phosphin

1, 3 - a double (diphenyl phosphine) propane

1,3-Bis(diphenylphosphino)propane Propane-1,3-diylbis(diphenylphosphine)

1-(phenyl(3-(diphenylphosphino)propyl)phosphino)benzene

,3-Bis(diphenylphosphino)propane

1,3-bis-(diphosphino)propane

1,3-Bis(diphenyL

phosphino)propane

1,3-BIS(DIPHENYPHOSPHINO)

1,3-Bis(diphenylphosphino)propane, C 77.5%, H 6.5%

1,3-Bis(diphenylphosphino)propane,97%

3-Di(phenyl)phosphanylpropyl-di(phenyl)phosphane

1,3-Bis(diphenylphosphino)propane ,98%

1,3-Bis(diphenylphosphino)propane, 97% 5GR

98% DPPP

1,3-Bis(diphenylphosphiNA)propane

1,3-Bis(diphenylphosphino)prop

Bis diphenylphosphino propane

Propane-1,3-diylbis(diphenylphosphane) 98%

Propane-1,3-diylbis(diphenylphosphine), 1,3-Bis(diphenylphosphino)propane

1,3- double(twophenylphosphine groups)propane(DPPP)

1,3-Bis(diphenylphosphino)propane, 95+%

1,3-Bis(diphenylphosphino)propane &gt

1,3-Bis(diphenylphosphino)propane, 97%, for synthesis

Phosphine, 1,1'-(1,3-propanediyl)bis[1,1-diphenyl-

1,3- bis(diphenylphosphaneyI)propane (DPPP)

DPPP (1,3-Bis(Diphenylphosphino)Propane) extrapure, 98%

1,3-Bis(diphenylphosphanyl)propane

1,3-Bis(diphenylphosphino)propane - [B94371]

6737-42-4

C6H52PCH2CH2CH2PC6H52

C6H52PCH23PC6H52

C27H26P2

Phosphine Ligands

Phosphorus Compounds

Polydentate Phosphine Ligands

Catalysis and Inorganic Chemistry

Phosphine Ligands

Synthetic Organic Chemistry

Ligand