2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE

Product Name: 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE
CAS No.: 36314-97-3
Chemical Name: 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE
Synonyms: IFLAB-BB F2108-0197;4-Chloro-6-phenyl-2-pyrimidinamine;2-Amino-4-phenyl-6-chloropyrimidine;2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE;2-Pyrimidinamine, 4-chloro-6-phenyl-;4-Chloro-6-phenyl-pyrimidin-2-ylamine;2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB4136871
Molecular Formula: C10H8ClN3
Formula Weight: 205.64
MOL File: 36314-97-3.mol

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2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE Property

Boiling point:: 433.1±37.0 °C(Predicted)
Density: 1.323±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.02±0.10(Predicted)
Appearance: Off-white to light yellow Solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FA147828
Product name: 2-Amino-4-chloro-6-phenylpyrimidine
Packaging: 1g
Price: $282
Updated: 2021/12/16

Matrix Scientific

Product number: 136660
Product name: 4-Chloro-6-phenylpyrimidin-2-amine
Purity: 95%+
Packaging: 1g
Price: $436
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA147828
Product name: 2-Amino-4-chloro-6-phenylpyrimidine
Packaging: 2g
Price: $491
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA147828
Product name: 2-Amino-4-chloro-6-phenylpyrimidine
Packaging: 500mg
Price: $160
Updated: 2021/12/16

Matrix Scientific

Product number: 136660
Product name: 4-Chloro-6-phenylpyrimidin-2-amine
Purity: 95%+
Packaging: 2.500g
Price: $953
Updated: 2021/12/16

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2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

56-05-3

98-80-6

36314-97-3

Example 2 Preparation of Compound 2 Step A - Synthesis of Compound 2b: To a reaction flask was added 2-amino-4,6-dichloropyrimidine (2.0 g, 12.2 mmol), acetonitrile (40 mL), potassium carbonate (2M aqueous solution, 6.1 mL, 12.2 mmol), tetrakis(triphenylphosphine)palladium (0.35 g, 0.31 mmol), and phenylboronic acid (0.74 g 6.1 mmol). The reaction mixture was stirred and heated to 90 °C and kept for 4 hours. After completion of the reaction, it was cooled to room temperature, transferred to a partition funnel, dichloromethane (50 mL) and water (50 mL) were added and mixed thoroughly to separate the organic layer. The aqueous layer was extracted with dichloromethane, the organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated. Purification by preparative thin layer chromatography (unfolding agent: 100% dichloromethane) afforded 2-amino-4-chloro-6-phenylpyrimidine (0.8 g, 64% yield).

References

[1] Patent: WO2009/111449, 2009, A1. Location in patent: Page/Page column 38-39
[2] Patent: WO2015/187089, 2015, A1. Location in patent: Page/Page column 65
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 9, p. 2303 - 2308
[4] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 16, p. 3670 - 3674
[5] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 8, p. 2497 - 2501

2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE Suppliers

Canada 1 China 64 Germany 1 India 1 Russia 1 United Kingdom 5 United States 15 Global 88

3B Pharmachem (Wuhan) International Co.,Ltd.

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View Lastest Price from 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE 36314-97-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-17

Career Henan Chemical Co

Product: 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE 36314-97-3
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-02-21

36314-97-3, 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINERelated Search:

2-Aminopyrimidine 2-Amino-4-chloro-6-methylpyrimidine 4-METHYL-6-CHLORO PYRIMIDINE 2-Amino-4-methylpyrimidine 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE 2-Amino-4-chloropyrimidine 4-Phenylpyrimidine 4-PHENYLPYRIMIDIN-2-AMINE

IFLAB-BB F2108-0197

2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE

4-Chloro-6-phenyl-2-pyrimidinamine

2-Amino-4-phenyl-6-chloropyrimidine

2-Pyrimidinamine, 4-chloro-6-phenyl-

4-Chloro-6-phenyl-pyrimidin-2-ylamine

2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE ISO 9001：2015 REACH

36314-97-3

pyrimidine

Heterocycle-Pyrimidine series