ChemicalBook > CAS DataBase List > 1-deazaadenosine
1-deazaadenosine
- Product Name
- 1-deazaadenosine
- CAS No.
- 14432-09-8
- Chemical Name
- 1-deazaadenosine
- Synonyms
- 1-deazaadenosine;Deazaadenosine, 1-;1 Deazaadenosine,1Deazaadenosine;3-β-D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine;3H-Imidazo[4,5-b]pyridin-7-amine, 3-β-D-ribofuranosyl-;3H-IMidazo[4,5-b]pyridin-7-aMine, 3-b-D-ribofuranosyl-;3-beta-D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine;7-Amino-3-(β-D-ribofuranosyl)-3H-imidazo[4,5-b]pyridine
- CBNumber
- CB41392102
- Molecular Formula
- C11H14N4O4
- Formula Weight
- 266.25326
- MOL File
- 14432-09-8.mol
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1-deazaadenosine Property
- Melting point:
- 263-264 °C (decomp)(Solv: water (7732-18-5))
- Boiling point:
- 674.6±65.0 °C(Predicted)
- Density
- 1.90±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble to 25 mM in DMSO
- form
- Powder
- pka
- 13.21±0.70(Predicted)
- color
- White to off-white
- InChI
- InChI=1/C11H14N4O4/c12-5-1-2-13-10-7(5)14-4-15(10)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/s3
- InChIKey
- NVUDDRWKCUAERS-SOMIAQKHNA-N
- SMILES
- C12N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C=NC1=C(N)C=CN=2 |&1:2,4,7,9,r|
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N-Bromosuccinimide Price
Tocris
- Product number
- 4488
- Product name
- 1-Deazaadenosine
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $280
- Updated
- 2021/12/16
TRC
- Product number
- D203228
- Product name
- 1-Deazaadenosine
- Packaging
- 2.5mg
- Price
- $330
- Updated
- 2021/12/16
Usbiological
- Product number
- 254328
- Product name
- 1-Deazaadenosine
- Packaging
- 10mg
- Price
- $588
- Updated
- 2021/12/16
Axon Medchem
- Product number
- Axon2434
- Product name
- 1-Deazaadenosine
- Purity
- 99%
- Packaging
- 5mg
- Price
- $148.5
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B5619
- Product name
- 1-Deazaadenosine
- Packaging
- 10mg
- Price
- $417
- Updated
- 2021/12/16
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1-deazaadenosine Chemical Properties,Usage,Production
Uses
1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders[1][2].
storage
Store at +4°C
References
[1] Cristalli G, et al.Adenosine deaminase inhibitors: Structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogues. Drug Dev.Res.
[2] Cristalli G, et al.Improved synthesis and antitumor activity of 1-deazaadenosine.J Med Chem. 1987 Sep;30(9):1686-8. DOI:10.1021/jm00392a029
1-deazaadenosine Preparation Products And Raw materials
Raw materials
Preparation Products
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1-deazaadenosine Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77