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INTERMEDINE

Product Name
INTERMEDINE
CAS No.
10285-06-0
Chemical Name
INTERMEDINE
Synonyms
C10330;INTERMIDINE;Intermedine-RM;(+)-Intermedine;9-(+)-Trachelanthylretronecine;(1R)-2,3,5,7aβ-Tetrahydro-7-[[(2S,3R)-2-isopropyl-2,3-dihydroxybutyryl]oxymethyl]-1H-pyrrolizine-1-ol;(2S,3R)-2,3-Dihydroxy-2-isopropylbutanoic acid [[(5R,6R)-6-hydroxy-1-azabicyclo[3.3.0]oct-3-en-4-yl]methyl] ester;Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-
CBNumber
CB41405433
Molecular Formula
C15H25NO5
Formula Weight
299.36
MOL File
10285-06-0.mol
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INTERMEDINE Property

Melting point:
140-141 °C
Boiling point:
463.3±45.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
pka
12.59±0.29(Predicted)
form 
Solid
color 
White to off-white
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Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
I666660
Product name
Intermedine
Packaging
0.5mg
Price
$260
Updated
2021/12/16
TRC
Product number
I666660
Product name
Intermedine
Packaging
5mg
Price
$2080
Updated
2021/12/16
Biosynth Carbosynth
Product number
XI161638
Product name
Intermedine
Packaging
1mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
XI161638
Product name
Intermedine
Packaging
2mg
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
XI161638
Product name
Intermedine
Packaging
5mg
Price
$500
Updated
2021/12/16
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INTERMEDINE Chemical Properties,Usage,Production

Uses

Intermedine-D7 is a labelled analogue of Intermedine (I666660). Intermedine is an unsaturated monoester pyrrolizidine alkaloid that is extracted from the seeds of Amsinckia intermedia, a tarweed that causes enzootic hepatic cirrhosis in horses and hard liver disease in cattle. Intermedine is also a diastereomer of Lycopsamine (L487525), a pyrrolizidine alkaloid that is found in honey and in comfrey (a topical anti-inflammatory agent used to treat patients with arthritis and gout).

Definition

ChEBI: A carboxylic ester compound formed from condensation between retronecine and (2S,3R)-2,3-dihydroxy-2-isopropylbutanoic acid.

INTERMEDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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INTERMEDINE Suppliers

China 28 France 1 India 1 United Kingdom 1 United States 1 Global 32
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

10285-06-0, INTERMEDINERelated Search:

retronecine INTERMEDINE SUPININE

  • INTERMIDINE
  • (1R)-2,3,5,7aβ-Tetrahydro-7-[[(2S,3R)-2-isopropyl-2,3-dihydroxybutyryl]oxymethyl]-1H-pyrrolizine-1-ol
  • (2S,3R)-2,3-Dihydroxy-2-isopropylbutanoic acid [[(5R,6R)-6-hydroxy-1-azabicyclo[3.3.0]oct-3-en-4-yl]methyl] ester
  • 9-(+)-Trachelanthylretronecine
  • C10330
  • Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-
  • (+)-Intermedine
  • Intermedine-RM
  • 10285-06-0