BACCHARIN
- Product Name
- BACCHARIN
- CAS No.
- 61251-97-6
- Chemical Name
- BACCHARIN
- Synonyms
- BACCHARIN;BACCHARINB5;BACCHARINOIDB5;(2'S,3'R,4'S,7'R,9R,10S)-7'-Deoxo-2'-deoxy-2',3':9,10-bisoxy-9,10-dihydro-4'-hydroxy-7'-[(R)-1-hydroxyethyl]verrucarin A;Verrucarin A, 7'-deoxo-2'-deoxy-2',3':9,10-diepoxy-9,10-dihydro-4'-hydroxy-7'-[(1R)-1-hydroxyethyl]-, (2'S,3'R,4'S,7'R,9R,10S)-
- CBNumber
- CB41419373
- Molecular Formula
- C29H38O11
- Formula Weight
- 562.61
- MOL File
- 61251-97-6.mol
Safety
- RIDADR
- 3172
- HazardClass
- 6.1(a)
- PackingGroup
- I
N-Bromosuccinimide Price
- Product number
- PXT0002386
- Product name
- BACCHARIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.1
- Updated
- 2021/12/16
BACCHARIN Chemical Properties,Usage,Production
Enzyme inhibitor
This anti-leukemia agent (FW = 562.61 g/mol; CAS 61251-97-6), also named (2'S,3'R,4'S, 7'R,9R,10S)-7'-deoxo-2'-deoxy-2',3':9,10-bisoxy-9,10- dihydro-4'-hydroxy-7'-[(R)-1-hydroxyethyl]verrucarin A, from the toxic South American plant known as green propolis (Baccharis megapotamica), is a likely mycotoxin that was later modified by Baccharis megapotamica. Baccharin is also a potent competitive inhibitor (Ki = 56 nM) of human aldo-keto reductase (AKR) 1C3, also known as 17β-hydroxysteroid dehydrogenase (Type 5) and prostaglandin F synthase. AKR is regarded as a druggable target in the treatment of prostate and breast cancers. Baccharin shows no significant inhibition toward the AKR1C1, AKR1C2, and AKR1C4 isoforms. Moreover, non-prenyl analogues of baccharin as selective and potent inhibitors for AKR1C3.
BACCHARIN Preparation Products And Raw materials
Raw materials
Preparation Products
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