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N-ISOBUTYL-2,6,8-DECATRIENAMIDE

Product Name
N-ISOBUTYL-2,6,8-DECATRIENAMIDE
CAS No.
25394-57-4
Chemical Name
N-ISOBUTYL-2,6,8-DECATRIENAMIDE
Synonyms
AFFININ;SPILANTHOL;SPILANTHOL(P);Spilanthol (Affinin);spilanthol(25394-57-4);Spilanthol (Technical Grade);N-ISOBUTYL-2,6,8-DECATRIENAMIDE;Nano-Liposomal ACMELLA OLERACEA EXTRACT;(2E,6Z,8E)-N-Isobutyl-2,6,8-decatrienamide;2,6,8-DecatrienaMide,N-(2-Methylpropyl)-, (2E,6Z,8E)-
CBNumber
CB41434697
Molecular Formula
C14H23NO
Formula Weight
221.34
MOL File
25394-57-4.mol
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N-ISOBUTYL-2,6,8-DECATRIENAMIDE Property

Melting point:
23°
Boiling point:
bp0.2 141°; bp0.3-0.5 160-165°
Density 
0.896±0.06 g/cm3(Predicted)
refractive index 
nD25 1.5134
FEMA 
4668 | (2E,6E/Z,8E)-N-(2-METHYLPROPYL)-2,6,8-DECATRIENAMIDE
storage temp. 
Amber Vial, -86°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
15.07±0.46(Predicted)
form 
Solid
color 
Colourless to Yellow Oil
Odor
at 100.00 %. fruity
Odor Type
fruity
JECFA Number
2077
Stability:
Light Sensitive, Temperature Sensitive
LogP
3.18
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Safety

Toxicity
LD50 oral in mouse: 4378mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
S681850
Product name
SpilantholAmixtureof(2E,6Z,8E)>80%;(2E,6E,8E);and(2E,6Z,8Z)
Packaging
1mg
Price
$205
Updated
2021/12/16
TRC
Product number
S681850
Product name
SpilantholAmixtureof(2E,6Z,8E)>80%;(2E,6E,8E);and(2E,6Z,8Z)
Packaging
10mg
Price
$1620
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
48719
Product name
Spilanthol
Packaging
50mg
Price
$2200
Updated
2021/12/16
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N-ISOBUTYL-2,6,8-DECATRIENAMIDE Chemical Properties,Usage,Production

Uses

Spilanthol is a fatty acid amide isolated from Acmella oleracea. Spilanthol extract has been discovered to aid in saliva stimulation (sialogogue) for people suffering from dry mouth (xerostomia).

Uses

Insecticide synergist.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 5177, 1984 DOI: 10.1016/S0040-4039(01)81556-2

in vivo

Spilanthol ( 1-1.875 mg/kg, Ip, Once) shows antinociceptive activity in acetic acid-induced abdominal writhes Male ICR mice model and capsaicin-induced licking paw Male ICR mice model[2].
Spilanthol (30 mg/kg, Po, Once a day for four days) a protective effect against the intestinal damage associated in swiss mice model of intestinal mucositis induced by 5-fluorouracil (HY-90006)[4].
Spilanthol (800 mg/kg, Po, Once) has a diuretic effect in adult C57BL/6J male mice[5].

Animal Model:Acetic acid-induced abdominal writhes Male ICR mice model[2]
Dosage:1-1.875 mg/kg
Administration:Intraperitoneal administration(i.p.), Once
Result:As the dose increased, the number of abdominal contractions and licking behavior decreased, and a maximum antinociceptive effect of 46.67%
Animal Model:Swiss mice model of intestinal mucositis induced by 5-fluorouracil[4].
Dosage:30 mg/kg
Administration:Oral adminstraion(p.o.), Once a day for four days
Result:Showed the intestinal wall recovery, villi are higher and less irregularity and high number and greater length of intestinal crypts.
Animal Model:Adult C57BL/6J male mice[5].
Dosage:800 mg/Kg
Administration:Oral adminstraion (p.o.), Once
Result:Increased in urine output, sodium, and increased excretion of sodium, potassium and chloride.

N-ISOBUTYL-2,6,8-DECATRIENAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-ISOBUTYL-2,6,8-DECATRIENAMIDE Suppliers

Canada 1 China 43 India 3 United States 4 USA 1 Global 52
J & K SCIENTIFIC LTD.
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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View Lastest Price from N-ISOBUTYL-2,6,8-DECATRIENAMIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Spilanthol 25394-57-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
1-40%
Supply Ability
100KG
Release date
2025-09-11

25394-57-4, N-ISOBUTYL-2,6,8-DECATRIENAMIDERelated Search:


  • N-ISOBUTYL-2,6,8-DECATRIENAMIDE
  • SPILANTHOL
  • AFFININ
  • (2E,6Z,8E)-N-Isobutyl-2,6,8-decatrienamide
  • SPILANTHOL(P)
  • 2,6,8-DecatrienaMide,N-(2-Methylpropyl)-, (2E,6Z,8E)-
  • spilanthol(25394-57-4)
  • 2,6,8-Decatrienamide,N-(2-methylpropyl)-, (2E,6Z,8E)- CAS NO.25394-57-4
  • Nano-Liposomal ACMELLA OLERACEA EXTRACT
  • Spilanthol A mixture of (2E, 6Z, 8E) >80%, (2E, 6E, 8E), and (2E, 6Z, 8Z)
  • Spilanthol (Technical Grade)
  • Spilanthol (Affinin)
  • 25394-57-4