ChemicalBook > CAS DataBase List > FRAXINOL

FRAXINOL

Product Name: FRAXINOL
CAS No.: 486-28-2
Chemical Name: FRAXINOL
Synonyms: Fraxil;FRAXINOL;Fraxinol-RM;Fraxinol, 10 mM in DMSO;5,7-Dimethoxy-6-hydroxycoumarin;6-Hydroxy-5,7-dimethoxycoumarin;6-Hydroxy-5,7-dimethoxy-chromen-2-one;6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one;6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-
CBNumber: CB41437012
Molecular Formula: C11H10O5
Formula Weight: 222.19
MOL File: 486-28-2.mol

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FRAXINOL Property

Melting point:: 170-172℃
Boiling point:: 449.7±45.0 °C(Predicted)
Density: 1.358
storage temp.: Store at -20°C
solubility: Soluble in DMSO and methanol;
pka: 8.95±0.20(Predicted)
form: powder
color: White-yellowish
Water Solubility: slightly soluble in water
CAS DataBase Reference: 486-28-2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28218
Product name: Fraxinol
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 28218
Product name: Fraxinol
Packaging: 10mg
Price: $310
Updated: 2024/03/01

Cayman Chemical

Product number: 28218
Product name: Fraxinol
Packaging: 5mg
Price: $179
Updated: 2024/03/01

Usbiological

Product number: 361791
Product name: Fraxinol
Packaging: 20mg
Price: $581
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594389
Product name: Fraxinol
Packaging: 20mg
Price: $591.6
Updated: 2021/12/16

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FRAXINOL Chemical Properties,Usage,Production

Description

Fraxinol is a coumarin originally isolated from Ash tree bark. It inhibits growth of GLC-4 small cell lung carcinoma and COLO 320 colorectal cancer cells (IC₅₀s = 193 and 165 μM, respectively). Fraxinol potentiates barbiturate-induced sleep in rats and rabbits.

Chemical Properties

White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the fraxinus chinensis tree.

Uses

Fraxinol is isolated from Lobelia chinensis[1].

References

[1] Wei J, et al. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharm Biol. 2018 Dec;56(1):363-367. DOI:10.1080/13880209.2018.1491999

FRAXINOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from FRAXINOL manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Fraxinol 486-28-2
Price: US $0.00-0.00/KG
Min. Order: 5mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-07

Career Henan Chemical Co

Product: 6-hydroxy-5,7-dimethoxychromen-2-one 486-28-2
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

486-28-2, FRAXINOLRelated Search:

MURRAYAE FOLIUM ET CACUMEN ISOBERGAPTOL pimpinellin WEDELOLACTONE 5,8-DIHYDROXYPSORALEN 4-METHYLESCULETIN FRAXIN MEDICAGOL 6-ISOPENTENYLOXYISOBERGAPTEN 4-Hydroxycoumarin 5-Hydroxyxanthotoxin 5,7-Dihydroxy-4-methylcoumarin 5,7-Dimethoxycoumarin

FRAXINOL

5,7-Dimethoxy-6-hydroxycoumarin

6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one

6-Hydroxy-5,7-dimethoxycoumarin

Fraxil

6-Hydroxy-5,7-dimethoxy-chromen-2-one

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one

2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-

Fraxinol-RM

Fraxinol, 10 mM in DMSO

486-28-2