ChemicalBook > CAS DataBase List > 5-METHOXYURIDINE

5-METHOXYURIDINE

Product Name
5-METHOXYURIDINE
CAS No.
35542-01-9
Chemical Name
5-METHOXYURIDINE
Synonyms
1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione;mo(5)U;5-METHOXYURIDINE;5-MethoxyuridineA;Uridine, 5-methoxy-;5 –Methoxyuridine,RNA anticodon nucleoside for RNA vaccines and geno mics,P2Y6 receptor agonist;1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-1,2,3,4-tetrahydropyrimidine-2,4-dione
CBNumber
CB4144845
Molecular Formula
C10H14N2O7
Formula Weight
274.23
MOL File
35542-01-9.mol
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5-METHOXYURIDINE Property

Density 
1.65±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
pka
8?+-.0.10(Predicted)
form 
Solid
color 
White to off-white
λmax
279 (pH 2)；277 (pH 12)
InChI
InChI=1S/C10H14N2O7/c1-18-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)19-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChIKey
ZXIATBNUWJBBGT-JXOAFFINSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(OC)C(=O)NC2=O)[C@H](O)[C@@H]1O
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Safety

WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M271740
Product name
5-Methoxyuridine
Packaging
25mg
Price
$145
Updated
2021/12/16
Usbiological
Product number
296272
Product name
5-Methoxyuridine
Packaging
10mg
Price
$375
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0164828
Product name
5-METHOXYURIDINE
Purity
98.00%
Packaging
0.5G
Price
$1416.8
Updated
2021/12/16
Biosynth Carbosynth
Product number
NM08028
Product name
5-Methoxyuridine
Packaging
10mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
8230AJ
Product name
5-Methoxyuridine
Packaging
100mg
Price
$482
Updated
2021/12/16
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5-METHOXYURIDINE Chemical Properties,Usage,Production

Description

5-Methoxyuridine is an intermediate in the biosynthesis of pyrimidines and is also used as a precursor for other compounds. 5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist. It inhibits messenger RNA (mRNA) production in bacteria by interfering with sequence recognition and binding sites within the ribosome and preventing.

Chemical Properties

Solid

Uses

5-Methoxyuridine is an analog of Uridine (U829910) and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist.

Definition

ChEBI: A derivative of uridine, bearing an additional methoxy substituent at position 5 on the uracil ring.

Synthesis

5-Hydroxyuridine was synthesized by the method described by T. Ueda. 5-Hydroxyuridine (30 mg) was further methylated by 20 y1 of dimethyl sulfate in 0.6 ml of 0.1 N NaOH. A reaction mixture was chromatographed on Whatman 3MM paper using solvent D. The band containing 5-Hydroxyuridine was extracted with water and the extract was further purified by paper chromatography in sol vent E. These procedures gave a 25% yield of mo5l). In addition to 5-Hydroxyuridine and the raw material, the methylated products contained 5% of 5-hydroxy-3-methyl uridine and 4% of 5-methoxy-3-methyluridine.

5-METHOXYURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHOXYURIDINE Suppliers

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View Lastest Price from 5-METHOXYURIDINE manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-METHOXYURIDINE 35542-01-9
Price
US $10.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-28

35542-01-9, 5-METHOXYURIDINERelated Search:

2-HYDROXYETHYLUREA (Hydroxymethyl)urea 3-Methylamino-1,2-propanediol 3-Dimethylamino-1-propanol 4,6-Dihydroxy-5-methoxypyrimidine (E)-3-(Dimethylamino)-2-methoxyacrylaldehyde 2'-Deoxyuridine 2',3'-Dideoxyuridine 5-HYDROXYURIDINE Uridine 3-Dimethylaminopropane-1,2-diol N-Butylurea 2-HYDROXYACETAMIDE N-(2-METHOXYETHYL)UREA 5-METHOXYURIDINE 1-METHYLURACIL 3'-DEOXYURIDINE N-hydroxymethyl-N-methylformamide

  • 5-METHOXYURIDINE
  • mo(5)U
  • Uridine, 5-methoxy-
  • 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione
  • 5 –Methoxyuridine,RNA anticodon nucleoside for RNA vaccines and geno mics,P2Y6 receptor agonist
  • 5-MethoxyuridineA
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 35542-01-9
  • C10H14N2O7
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • BioChemical
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides