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3-Methylamino-1,2-propanediol

Product Name
3-Methylamino-1,2-propanediol
CAS No.
40137-22-2
Chemical Name
3-Methylamino-1,2-propanediol
Synonyms
3-Methylamino-1,2-Propandiol;3-METHYLAMINO-1,2-PROPANEDIOL;3-METHYLAMINO-PROPANE-1,2-DIOL;3-(methylamino)propane-1,2-dio;3-(AMINOMETHYL)-1,2-PROPANEDIOL;N-METHYL-3-AMINO-1,2-PROPANEDIOL;3-Methylamino-1,2-propanediol>1,2-Propanediol, 3-(methylamino)-;N-Methyl-2,3-dihydroxypropylamine;2,3-Dihydroxy-N-methylpropylamine
CBNumber
CB9174021
Molecular Formula
C4H11NO2
Formula Weight
105.14
MOL File
40137-22-2.mol
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3-Methylamino-1,2-propanediol Property

Melting point:
69°C (estimate)
Boiling point:
247 °C
Density 
1.095 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.476
Flash point:
152 °C
storage temp. 
Inert atmosphere,Room Temperature
pka
14.09±0.20(Predicted)
form 
clear liquid
color 
Colorless to Almost colorless
Specific Gravity
1.0921
PH
11.5 (100g/l, H2O, 20℃)
Water Solubility 
miscible
BRN 
1733341
CAS DataBase Reference
40137-22-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
RIDADR 
2735
WGK Germany 
3
3-10-34
HazardClass 
8
PackingGroup 
II
HS Code 
29221980
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M1243
Product name
3-Methylamino-1,2-propanediol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$57
Updated
2024/03/01
Alfa Aesar
Product number
L12653
Product name
3-Methylamino-1,2-propanediol, 99%
Packaging
25g
Price
$39.65
Updated
2024/03/01
Alfa Aesar
Product number
L12653
Product name
3-Methylamino-1,2-propanediol, 99%
Packaging
100g
Price
$115.65
Updated
2024/03/01
TRC
Product number
M332493
Product name
3-Methylamino-1,2-propanediol
Packaging
5g
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
091200
Product name
3-(Methylamino)propane-1,2-diol
Purity
98%
Packaging
5g
Price
$61
Updated
2021/12/16
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3-Methylamino-1,2-propanediol Chemical Properties,Usage,Production

Description

3-Methylamino-1,2-propanediol (MAPD) is a clear liquid with the chemical formula C4H11NO2. It can be synthesized from allylamine and alkanolamine via a thermal process. It reacts with chloride to form methyl chloroacetate, which can then be converted into 3-methylamino-1,2-propanediol by reaction with methanol. The production process for this substance has been shown to generate low levels of hazardous substances such as polycyclic aromatic hydrocarbons (PAHs) and dioxins.

Chemical Properties

clear colorless to pale yellow viscous liquid

Uses

3-Methylamino-1,2-propanediol is a reactive compound that is used in the synthesis of organic acids. It is also used as an intermediate in the manufacture of polyethylene glycols and particle coatings.

Definition

ChEBI: 3-methylamino-1,2-propanediol is a secondary amine.

Preparation

3-Methylamino-1,2-propanediol (MAPD) is synthesized by reacting 3-chloro-1,2-propanediol (CPD) with monomethyl amine in alkaline environment by adding sodium hydroxide. Afterwards, the product undergoes a series of purification steps.  

N-Methyl-1-amino-2,3-propandiol (45A) Methylamine (172ml of a 40% solution in water, 2 mol) was cooled to 0 °C and 2,3-epoxy-1-propanol (25g, 0.34mol) was added at a rate to maintain the temperature at or below 10 °C. The mixture was stirred for 3 hours at 0 °C. Excess methylamine and water was evaporated in vacuo and the product was purified by distillation at 103-105 °C, at 0.5 mm Hg, to give the compound 3-Methylamino-1,2-propanediol.

Hazard

3-Methylamino-1,2-propanediol is danger.
H314 (32.76%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H315 (67.24%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (65.52%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

3-Methylamino-1,2-propanediol Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Methylamino-1,2-propanediol Suppliers

Saintchem Chemical Co., Ltd.
Tel
13968039099 +undefined-13968039099
Fax
+86-483-8188266
Email
cherry.zhang@saintchem.com
Country
China
ProdList
10
Advantage
60
Yangzhou Prince Chemical Co., Ltd
Tel
0514-84248359 13328140016
Email
sales@princechem.com
Country
China
ProdList
99
Advantage
58
Yangzhou Princechem Co.,Ltd
Tel
18921928333
Email
david@princechem.com
Country
China
ProdList
342
Advantage
58
Shanghai Lankun Pharmaceutical Technology Co., Ltd
Tel
18616122638
Email
saleslee@kunrising.com
Country
China
ProdList
23
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12438
Advantage
60
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View Lastest Price from 3-Methylamino-1,2-propanediol manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
3-Methylamino-1,2-propanediol 40137-22-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-08-20
Henan Fengda Chemical Co., Ltd
Product
3-Methylamino-1,2-propanediol 40137-22-2
Price
US $32.00-1.50/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-22
Henan Aochuang Chemical Co.,Ltd.
Product
3-Methylamino-1,2-propanediol 40137-22-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-27

40137-22-2, 3-Methylamino-1,2-propanediolRelated Search:


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