6-AZAURIDINE

Product Name: 6-AZAURIDINE
CAS No.: 54-25-1
Chemical Name: 6-AZAURIDINE
Synonyms: azauridine;6-azuridine;azur;6-azur;nsc32074;AZURIDINE;Aids008706;Aids-008706;6-AZAURIDINE;ribo-azuracil
CBNumber: CB1413830
Molecular Formula: C8H11N3O6
Formula Weight: 245.19
MOL File: 54-25-1.mol

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6-AZAURIDINE Property

Melting point:: 157-159 °C(lit.)
Boiling point:: 388.15°C (rough estimate)
Density: 1.4866 (rough estimate)
refractive index: 1.7950 (estimate)
storage temp.: 2-8°C
solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly), Water
form: Powder
pka: 6.70(at 25℃)
color: White
Water Solubility: It is soluble in water.
Merck: 14,904
Stability:: Hygroscopic
InChIKey: WYXSYVWAUAUWLD-YGWZKZRUSA-N
CAS DataBase Reference: 54-25-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-40
Safety Statements: 22-36
WGK Germany: 3
RTECS: XY8575000
HS Code: 29349990
Hazardous Substances Data: 54-25-1(Hazardous Substances Data)
Toxicity: LD50 oral in quail: > 316mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A1882
Product name: 6-Azauridine
Packaging: 1g
Price: $86.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: A1882
Product name: 6-Azauridine
Packaging: 5g
Price: $481
Updated: 2024/03/01

TCI Chemical

Product number: A0559
Product name: 6-Azauridine
Purity: >99.0%(HPLC)
Packaging: 10mg
Price: $30
Updated: 2024/03/01

Alfa Aesar

Product number: J61309
Product name: 6-Azauridine
Packaging: 1g
Price: $118.65
Updated: 2024/03/01

Alfa Aesar

Product number: J61309
Product name: 6-Azauridine
Packaging: 5g
Price: $471.65
Updated: 2024/03/01

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6-AZAURIDINE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.

Uses

6-Azauridine (AzUrd) blocks the conversion of orotic acid into UMP and it is used in antiviral studies.

Uses

Research on cell formation and cancer.

Definition

ChEBI: 6-azauridine is a N-glycosyl-1,2,4-triazine. It has a role as an antineoplastic agent, an antimetabolite and a drug metabolite.

General Description

6-Azauridine is a pyrimidine nucleoside analog.

Biochem/physiol Actions

6-azauridine is a prodrug, upon conversion to 6-aza-UMP, inhibits uridine monophosphate synthase (UMPS). It is a broad spectrum anti-metabolite. It interferes with pyrimidine biosynthesis and affects the cellular nucleic acid levels. It is considered as a antineoplastic metabolite. It inhibits RNA viruses like chikungunya virus, semliki forest virus, and human coronavirus. It significantly inhibits the growth of Cryptosporidium parasites.

6-AZAURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-AZAURIDINE Suppliers

Americas 1 China 80 Europe 1 Germany 2 India 2 Japan 1 Russia 1 Switzerland 3 United Kingdom 10 United States 17 Global 118

Panaishen (Henan) Pharmaceutical Science and Technology Co. , Ltd.

Tel: 0371-65325800 13700860222
Email: haifeng.zhang@pannacean.com
Country: China
ProdList: 637
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

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View Lastest Price from 6-AZAURIDINE manufacturers

Career Henan Chemical Co

Product: 6-AZAURIDINE 54-25-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

Career Henan Chemical Co

Product: 6-AZAURIDINE 54-25-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-24

54-25-1, 6-AZAURIDINERelated Search:

6-AZAURIDINE 2',3',5'-TRIACETATE Semicarbazide 2-Hydroxyethylhydrazine (Hydroxymethyl)urea 2-HYDROXYETHYLUREA 6-AZAURIDINE 3-Methylamino-1,2-propanediol 1,3-DIETHYLUREA 6-AZAURACIL N-Butylurea 6-Azauracil 6-AZA-2'-DEOXYURIDINE 6-AZAURIDINE-5'-MONOPHOSPHATE,6-Azauridine 5'-phosphoric acid N-ETHYL-N-FORMYLHYDRAZINE 5-Methyl-2'-deoxy-6-azauridine 2-THIO-6-AZAURIDINE 6-azauridine 5'-triphosphate 5-Azauridine

6-AZA-2,4-DIHYDROXYPYRIMIDINE RIBOSIDE

6-AZAURIDINE MONOHYDRATE

6-AZAURACIL RIBOSIDE

6-AZAURACIL RIBOSIDE MONOHYDRATE

6-AZAURIDINE

2-BETA-D-RIBOFURANOSYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE

AZAURIDINE, 6-

2-beta-d-ribofuranosyl-1,2,4-triazin-3,5(2h,4h)-dion

2-beta-d-ribofuranosyl-as-triazine-3,5(2h,4h)-dione

3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazineriboside

4h)-dione,2-beta-d-ribofuranosyl-as-triazine-5(2h

4-triazine-3,5(2h,4h)-dione,2-beta-d-ribofuranosyl-2

6-azauracil1-riboside

6-azauracil-beta-d-riboside

6-azauracilribosid

6-azur

6-azuridine

azauridine

azur

nsc32074

ribo-azuracil

2-(beta-D-ribofuranosyl)-1,2,4-triazine-3,5-diol

2-β-d-ribofuranosyl-1,2,4-triazine-3,5(2h,4h)-dione

AZURIDINE

TRIAZINE-3,5-DIONE,2-BETA-D-RIBOFURANOSYL-

6-Azauracil riboside, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione

Ribo-Azauracil

1,2,4-Triazine-3,5(2H,4H)-dione, 2-.beta.-D-ribofuranosyl-

Aids008706

Aids-008706

2-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione

1,2,4-Triazine-3,5(2H,4H)-dione,2-b-D-ribofuranosyl-

Rib-Azauracil

6-AZAURIDINE CRYSTALLINE

6-Azauridine&gt

1,2,4-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-

6-AZAURIDINE USP/EP/BP

6-Azauridine, antimetabolic antineoplastic agent

1-(beta-D-Ribofuranosyl)-6-azauracil

54-25-1

C8H11N3O6H2O

C8H11N3O6

Biochemicals and Reagents

BioChemical

Nucleosides, Nucleotides, Oligonucleotides

Nucleoside Analogs

Biochemistry

Nucleosides and their analogs

Nucleosides, Nucleotides & Related Reagents

Antibiotic Explorer

Pyridines, Pyrimidines, Purines and Pteredines