6-AZAURIDINE
- Product Name
- 6-AZAURIDINE
- CAS No.
- 54-25-1
- Chemical Name
- 6-AZAURIDINE
- Synonyms
- azauridine;6-azuridine;azur;6-azur;nsc32074;AZURIDINE;Aids008706;Aids-008706;6-AZAURIDINE;ribo-azuracil
- CBNumber
- CB1413830
- Molecular Formula
- C8H11N3O6
- Formula Weight
- 245.19
- MOL File
- 54-25-1.mol
6-AZAURIDINE Property
- Melting point:
- 157-159 °C(lit.)
- Boiling point:
- 388.15°C (rough estimate)
- Density
- 1.4866 (rough estimate)
- refractive index
- 1.7950 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly), Water
- form
- Powder
- pka
- 6.70(at 25℃)
- color
- White
- Water Solubility
- It is soluble in water.
- Merck
- 14,904
- Stability:
- Hygroscopic
- InChIKey
- WYXSYVWAUAUWLD-YGWZKZRUSA-N
- CAS DataBase Reference
- 54-25-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-40
- Safety Statements
- 22-36
- WGK Germany
- 3
- RTECS
- XY8575000
- HS Code
- 29349990
- Hazardous Substances Data
- 54-25-1(Hazardous Substances Data)
- Toxicity
- LD50 oral in quail: > 316mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A1882
- Product name
- 6-Azauridine
- Packaging
- 1g
- Price
- $86.1
- Updated
- 2024/03/01
- Product number
- A1882
- Product name
- 6-Azauridine
- Packaging
- 5g
- Price
- $481
- Updated
- 2024/03/01
- Product number
- A0559
- Product name
- 6-Azauridine
- Purity
- >99.0%(HPLC)
- Packaging
- 10mg
- Price
- $30
- Updated
- 2024/03/01
- Product number
- J61309
- Product name
- 6-Azauridine
- Packaging
- 1g
- Price
- $118.65
- Updated
- 2024/03/01
- Product number
- J61309
- Product name
- 6-Azauridine
- Packaging
- 5g
- Price
- $471.65
- Updated
- 2024/03/01
6-AZAURIDINE Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Uses
6-Azauridine (AzUrd) blocks the conversion of orotic acid into UMP and it is used in antiviral studies.
Uses
Research on cell formation and cancer.
Definition
ChEBI: 6-azauridine is a N-glycosyl-1,2,4-triazine. It has a role as an antineoplastic agent, an antimetabolite and a drug metabolite.
General Description
6-Azauridine is a pyrimidine nucleoside analog.
Biochem/physiol Actions
6-azauridine is a prodrug, upon conversion to 6-aza-UMP, inhibits uridine monophosphate synthase (UMPS). It is a broad spectrum anti-metabolite. It interferes with pyrimidine biosynthesis and affects the cellular nucleic acid levels. It is considered as a antineoplastic metabolite. It inhibits RNA viruses like chikungunya virus, semliki forest virus, and human coronavirus. It significantly inhibits the growth of Cryptosporidium parasites.
6-AZAURIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
6-AZAURIDINE Suppliers
- Tel
- --
- Fax
- --
- orders@chemical-block.com
- Country
- Russia
- ProdList
- 3905
- Advantage
- 61
View Lastest Price from 6-AZAURIDINE manufacturers
- Product
- 6-AZAURIDINE 54-25-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- as request
- Release date
- 2018-12-24
- Product
- 6-AZAURIDINE 54-25-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24