2-Bromo-5-cyano-3-picoline
- Product Name
- 2-Bromo-5-cyano-3-picoline
- CAS No.
- 374633-37-1
- Chemical Name
- 2-Bromo-5-cyano-3-picoline
- Synonyms
- 2-Bromo-5-cyano-picoline;6-Bromo-5-methylnicotinonitrile;2-Bromo-5-cyano-3-methylpyridine;6-Bromo-5-methyl-3-pyridinecarbonitrile;6-Bromo-5-methyl-pyridine-3-carbonitrile;3-Pyridinecarbonitrile, 6-broMo-5-Methyl-;2-Bromo-5-cyano-3-picoline ISO 9001：2015 REACH
- CBNumber
- CB41457078
- Molecular Formula
- C7H5BrN2
- Formula Weight
- 197.03
- MOL File
- 374633-37-1.mol
2-Bromo-5-cyano-3-picoline Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B678018
- Product name
- 2-Bromo-5-cyano-3-picoline
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FB142947
- Product name
- 6-Bromo-5-methylnicotinonitrile
- Packaging
- 500mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- OR914260
- Product name
- 2-Bromo-5-cyano-3-picoline
- Purity
- 95%
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 072633
- Product name
- 2-Bromo-5-cyano-3-picoline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 3H37-9-0Q
- Product name
- 2-Bromo-5-cyano-3-picoline
- Purity
- 95%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
2-Bromo-5-cyano-3-picoline Chemical Properties,Usage,Production
Synthesis
19158-51-1
374633-37-1
General procedure for the synthesis of 2-bromo-5-cyano-3-methylpyridine from 4-toluenesulfonyl cyanide: n-butyllithium (2.5 M hexane solution, 2.59 mL, 6.48 mmol) was added dropwise to an ether solution (65 mL) of 2,5-dibromo-3-methylpyridine (1.48 g, 5.89 mmol) at -78 °C. After 40 min of reaction, p-toluenesulfonyl cyanide (1.17 g, 6.49 mmol) was added, followed by slow warming of the reaction mixture to 0 °C. After completion of the reaction, the reaction was quenched with saturated aqueous NaHCO3 (50 mL) and extracted with CHCl3 (100 mL). The organic layer was dried with Na2S2O5 and concentrated to give the crude product. The crude product was purified by fast column chromatography (EtOAc/hexane as eluent) to give 310 mg (27% yield) of 2-bromo-5-cyano-3-methylpyridine as a white solid.
References
[1] Patent: US2007/232616, 2007, A1. Location in patent: Page/Page column 13
2-Bromo-5-cyano-3-picoline Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-5-cyano-3-picoline Suppliers
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
View Lastest Price from 2-Bromo-5-cyano-3-picoline manufacturers
- Product
- 2-Bromo-5-cyano-3-picoline 374633-37-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26