1-(4-Trifluoromethylpyrimidin-2-yl)piperazine
- Product Name
- 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine
- CAS No.
- 179756-91-3
- Chemical Name
- 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine
- Synonyms
- 2-PIPERAZIN-YL-4-(TRIFLUOROMETHYL)PYRIMIDINE;1-(4-Trifluoromethylpyrimidin-2-yl)piperazine;2-(1-Piperazinyl)-4-(trifluoromethyl)pyrimidine;2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine;1-[4-(Trifluoromethyl)pyrimid-2-yl]piperazine ,97%;Pyrimidine, 2-(1-piperazinyl)-4-(trifluoromethyl)-;1-[4-(TrifluoroMethyl)-2-pyriMidinyl]piperazine, 97%;1-(4-Trifluoromethylpyrimidin-2-yl)piperazine ISO 9001:2015 REACH
- CBNumber
- CB41471012
- Molecular Formula
- C9H11F3N4
- Formula Weight
- 232.21
- MOL File
- 179756-91-3.mol
1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Property
- Melting point:
- 50-52°C
- Boiling point:
- 331.3±52.0 °C(Predicted)
- Density
- 1.306±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 8.56±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P482505
- Product name
- 2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CHM0000799
- Product name
- 1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $808.89
- Updated
- 2021/12/16
- Product number
- CHM0000799
- Product name
- 1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1147.43
- Updated
- 2021/12/16
- Product number
- 085434
- Product name
- 2-Piperazin-1-yl-4-(trifluoromethyl)pyrimidine
- Purity
- 97%
- Packaging
- 10g
- Price
- $1344
- Updated
- 2021/12/16
- Product number
- CHM0000799
- Product name
- 1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1421.65
- Updated
- 2021/12/16
1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Chemical Properties,Usage,Production
Chemical Properties
Gray solid
Synthesis
110-85-0
33034-67-2
179756-91-3
2-Chloro-4-trifluoromethylpyrimidine (2.0 g, 11 mmol) and piperazine (2.8 g, 33 mmol) were dissolved in DMF (10 mL) and triethylamine (3.0 mL, 22 mmol) was added as base. The reaction mixture was placed in a sealed tube and the reaction was stirred at 100 °C overnight. After completion of the reaction, most of the solvent was removed under reduced pressure. The crude product was purified by silica gel column chromatography with EtOAc to EtOAc/MeOH/NEt3 (9:1:0.5) as eluent to afford 1-(4-trifluoromethylpyrimidin-2-yl)piperazine (1.48 g, 56% yield). Mass spectrometry analysis: the calculated value (M+H) of C9H11F3N4 was 233 and the measured value was 233.1.
References
[1] Patent: US2006/4018, 2006, A1. Location in patent: Page/Page column 37
1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine manufacturers
- Product
- 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine 179756-91-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-07
- Product
- 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine 179756-91-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24