H-D-Phe-Pip-Arg-pNA acetate

Product Name: H-D-Phe-Pip-Arg-pNA acetate
CAS No.: 115388-96-0
Chemical Name: H-D-Phe-Pip-Arg-pNA acetate
Synonyms: S 2238;S2238;S-2238 acetate;D-PHE-PIP-ARG-PNA;Chromogenix S-2765;D-PHE-PIP-ARG-PNA·2HCl;S-2238(Thrombin Substrate);N-α-Z-D-Arg-Gly-Arg-p·2HCl;H-D-Phe-Pip-Arg-pNA acetate;N-α-Z-D-Arg-Gly-Arg-pNA·2HCl;D-Phe-Pip-Arg-pNA (Pippipecolyl)
CBNumber: CB4148388
Molecular Formula: C29H40N8O7
Formula Weight: 612.69
MOL File: 115388-96-0.mol

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H-D-Phe-Pip-Arg-pNA acetate Property

storage temp.: −20°C
form: Solid
color: White to yellow
InChIKey: YVHLNJUMPNYROS-IAYLHCNXNA-N
SMILES: C(=O)(O)C.C([C@@H]1CCCCN1C(=O)[C@H](N)CC1C=CC=CC=1)(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1C=CC(N(=O)=O)=CC=1 |&1:5,13,24,r|

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38-63
Safety Statements: 26-36/37-45-36/37/39-22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Chem-Impex

Product number: 32947
Product name: H-D-Phe-Homopro-Arg-pNA·diacetate,≥98%(HPLC)
Purity: ≥98%(HPLC)
Packaging: 25MG
Price: $151.42
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0004471
Product name: D-PHE-PIP-ARG-PNA
Purity: 95.00%
Packaging: 5MG
Price: $505.18
Updated: 2021/12/16

DC Chemicals

Product number: DC9807
Product name: S-2238(ThrombinSubstrate)
Purity: >98%
Packaging: 100mg
Price: $750
Updated: 2021/12/16

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H-D-Phe-Pip-Arg-pNA acetate Chemical Properties,Usage,Production

Uses

H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform[1][2].

References

[1] Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. DOI:10.1093/ajcp/73.5.639
[2] Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353. PMID:6531759

H-D-Phe-Pip-Arg-pNA acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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H-D-Phe-Pip-Arg-pNA acetate Suppliers

China 72 France 1 Switzerland 1 United Kingdom 1 United States 7 Global 82

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115388-96-0, H-D-Phe-Pip-Arg-pNA acetateRelated Search:

Pipecolamide N,N'-DI-N-BUTYL-1,6-HEXANEDIAMINE N,N-DI-N-BUTYLETHYLENEDIAMINE N-(2-Aminoethyl)piperidine C-(1-METHYL-PIPERIDIN-2-YL)-METHYLAMINE 1-ACETYLPIPERIDINE H-D-Phe-Pip-Arg-pNA acetate N-methylpiperidine-2-carboxamide H-D-PHE-HOMOPRO-ARG-PNA 2 ACETATE N-acetyl-1,6-diaminohexane 2-(2-methylpiperidin-1-yl)ethanamine 2-AMINO-1-PIPERIDIN-1-YL-ETHANONE HCL N-[1-(aminomethyl)butyl]-N,N-dimethylamine 1-ethylpiperidine-2-methylamine Methyl[(1-methylpiperidin-2-yl)methyl]amine N-[(1-METHYL-2-PIPERIDINYL)METHYL]-1-PROPANAMINE N-[(1-BUTYL-2-PIPERIDINYL)METHYL]ETHANAMINE (1-BUTYL-2-PIPERIDINYL)-N-METHYLMETHANAMINE

D-PHE-PIP-ARG-PNA

D-PHE-L-PIPECOLYL-ARG P-NITROANILIDE*TRI ACETATE

D-Phe-Pip-Arg-pNA (Pippipecolyl)

H-D-Phe-Pip-Arg-pNA · 2 acetate, H-D-Phe-L-pipecolyl-Arg-pNA · 2 acetate

D-Phe-L-pipecolyl-Arg-p-nitroanilide dihydrochloride

S-2765,Chromogenic Substrate for Fxa

S-2238(Thrombin Substrate)

Chromogenix S-2765

D-PHE-PIP-ARG-PNA·2HCl

S 2238;S-2238;D-PHE-PIP-ARG-PNA·2HCL

S 2238;S2238

Factor Xa Chromogenic Substrate 1

H-D-Phe-Pip-Arg-pNA acetate

L-Argininamide-D-phenylalanyl-L-2-piperidinecarbonyl-N-(4-nitrophenyl) Acetic Acid

N-α-Z-D-Arg-Gly-Arg-pNA·2HCl

L-Argininamide,D-phenylalanyl-L-2-piperidinecarbonyl-N-(4-nitrophenyl)-,triacetate

S-2238 acetate

N-α-Z-D-Arg-Gly-Arg-p·2HCl

115388-96-0

C27H36N8O5

C27H38N8O5Cl2