3-Amino-2-methylphenylboronic acid, pinacol ester
- Product Name
- 3-Amino-2-methylphenylboronic acid, pinacol ester
- CAS No.
- 882678-96-8
- Chemical Name
- 3-Amino-2-methylphenylboronic acid, pinacol ester
- Synonyms
- 187589;(3-amino-3-methylphenyl)boronic acid;3-AMino-2-Metyl phenyl boronicacid pinacol ester;3-Amino-2-methylphenylboronic acid, pinacol ester;2-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)aniline;[2-Methyl-3-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)phenyl]aMine;BenzenaMine, 2-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline - [M87710]
- CBNumber
- CB41486469
- Molecular Formula
- C13H20BNO2
- Formula Weight
- 233.11
- MOL File
- 882678-96-8.mol
3-Amino-2-methylphenylboronic acid, pinacol ester Property
- Boiling point:
- 365.3±35.0 °C(Predicted)
- Density
- 1.03±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- pka
- 4.44±0.10(Predicted)
- form
- solid
- Appearance
- Off-white to light yellow Solid
- InChI
- InChI=1S/C13H20BNO2/c1-9-10(7-6-8-11(9)15)14-16-12(2,3)13(4,5)17-14/h6-8H,15H2,1-5H3
- InChIKey
- JMKMGPGFYMANCA-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BML00221
- Product name
- 3-Amino-2-methylphenylboronic acid pinacol ester
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $216
- Updated
- 2025/07/31
- Product number
- A634388
- Product name
- 3-Amino-2-methylphenylboronic acid pinacol ester
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA160880
- Product name
- 3-Amino-2-methylphenylboronic acid, pinacol ester
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- CS-0008630
- Product name
- 2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
- Purity
- ≥97.0%
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 096674
- Product name
- 2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $96
- Updated
- 2021/12/16
3-Amino-2-methylphenylboronic acid, pinacol ester Chemical Properties,Usage,Production
Synthesis
910235-64-2
882678-96-8
General procedure for the synthesis of 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline from 4,4,5,5-tetramethyl-2-(2-methyl-3-nitrophenyl)-1,3,2-dioxaborolan-2-yl)aniline: in a 500 mL round-bottomed flask 4,4,5,5-tetramethyl-2-(2-methyl-3-nitrophenyl) -1,3,2-dioxaborolane(6) (8.44 g, 32.1 mmol) and methanol (150 mL) in a 500 mL round-bottom flask equipped with a magnetic stirrer. After the reaction system was evacuated twice and replaced with argon, 10% palladium carbon catalyst (50% wet weight, 425 mg dry weight) was added. The reaction system was again evacuated and replaced with hydrogen three times. The reaction was stirred at room temperature for 13 hours under hydrogen balloon pressure. Upon completion of the reaction, the system was evacuated twice and replaced with argon, filtered through a diatomaceous earth pad (521) and the filtrate was concentrated under vacuum. The resulting residue was dried under high vacuum for 24 h to afford 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (7) in quantitative yield (8.16 g) as a white solid with a melting point of 110-112 °C; mass spectrum (ESI+) m/z 234 (M+H).
References
[1] Patent: US2009/82330, 2009, A1. Location in patent: Page/Page column 24
[2] Patent: WO2008/33858, 2008, A2. Location in patent: Page/Page column 130; 137
[3] Patent: WO2009/137596, 2009, A1. Location in patent: Page/Page column 69-70
[4] Patent: WO2008/33858, 2008, A2. Location in patent: Page/Page column 130; 137
[5] Patent: WO2009/77334, 2009, A1. Location in patent: Page/Page column 87
3-Amino-2-methylphenylboronic acid, pinacol ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Amino-2-methylphenylboronic acid, pinacol ester manufacturers
- Product
- 3-Amino-2-methylphenylboronic acid, pinacol ester 882678-96-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-14