2-Amino-5-ethyl-pyridine
Uses- Product Name
- 2-Amino-5-ethyl-pyridine
- CAS No.
- 19842-07-0
- Chemical Name
- 2-Amino-5-ethyl-pyridine
- Synonyms
- 5-ethylpyridin-2-aMine;5-ethyl-2-PyridinaMine;2-Pyridinamine, 5-ethyl-;2-Amino-5-ethyl-pyridine;5-ETHYL-PYRIDIN-2-YLAMINE;2-Amino-5-ethyl-pyridine ISO 9001：2015 REACH
- CBNumber
- CB41501267
- Molecular Formula
- C7H10N2
- Formula Weight
- 122.17
- MOL File
- 19842-07-0.mol
2-Amino-5-ethyl-pyridine Property
- Boiling point:
- 90-92 °C(Press: 3 Torr)
- Density
- 1.037±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 7.06±0.13(Predicted)
- Appearance
- Light yellow to brown Liquid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B439585
- Product name
- 5-ethylpyridin-2-amine
- Packaging
- 50mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- OR301037
- Product name
- 2-Amino-5-ethyl-pyridine
- Packaging
- 1g
- Price
- $531
- Updated
- 2021/12/16
- Product number
- CHM0094319
- Product name
- 2-PYRIDINAMINE, 5-ETHYL-
- Purity
- 95.00%
- Packaging
- 2G
- Price
- $1674.75
- Updated
- 2021/12/16
- Product number
- Y5080
- Product name
- 2-Amino-5-ethyl-pyridine
- Packaging
- 25g
- Price
- $2175
- Updated
- 2021/12/16
- Product number
- CHM0094319
- Product name
- 2-PYRIDINAMINE, 5-ETHYL-
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2607.41
- Updated
- 2021/12/16
2-Amino-5-ethyl-pyridine Chemical Properties,Usage,Production
Uses
5-Ethylpyridin-2-ylamine is a heterocyclic organic compound that can be used as a pharmaceutical intermediate.
Synthesis
1072-97-5
557-20-0
19842-07-0
General procedure for the synthesis of 5-ethylpyridin-2-amine from 2-amino-5-bromopyridine and diethylzinc: diethylzinc (24 mL, 1 M hexane solution, 24 mmol) was slowly added dropwise to a solution containing 2-amino-5-bromopyridine (2.0 g, 11.6 mmol) and Pd(dppf)Cl2-CH2Cl2 (225 mg, 0.28 mmol) in a degassed dioxane (45 mL) in solution. The reaction mixture was stirred at room temperature for 2 hours, followed by heating and refluxing for 3 hours and continued stirring at room temperature for 70 hours under argon protection. Upon completion of the reaction, the mixture was poured into saturated aqueous sodium chloride solution (150 mL) and extracted with ethyl acetate (4 x 100 mL). The organic phases were combined, washed with saturated aqueous sodium chloride solution (100 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by column chromatography (ethyl acetate/heptane followed by methanol/ethyl acetate) to afford the target compound 5-ethylpyridin-2-amine. Yield: 1.40 g (99%).1H NMR (DMSO-d6, 400 MHz) δ 7.74 (s, 1H), 7.25 (dd, 1H), 6.40 (d, 1H), 5.67 (br.s, 2H), 2.39 (q, 2H), 1.10 (t, 3H).
References
[1] Patent: WO2007/51981, 2007, A1. Location in patent: Page/Page column 60
[2] Patent: WO2007/51982, 2007, A1. Location in patent: Page/Page column 52
2-Amino-5-ethyl-pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-5-ethyl-pyridine manufacturers
- Product
- 5-ETHYL-PYRIDIN-2-YLAMINE 19842-07-0
- Price
- US $1.80-7.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-18
- Product
- 2-Amino-5-ethyl-pyridine 19842-07-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-12
- Product
- 2-Amino-5-ethyl-pyridine 19842-07-0
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-10