7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE

Product Name: 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE
CAS No.: 103361-99-5
Chemical Name: 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE
Synonyms: 7-Fluoro-4H-benzo[1,4]oxazin-3-one;7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE;7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H);2H-1,4-Benzoxazin-3(4H)-one, 7-fluoro-;7-FLUORO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE;7-FLUORO-2,4-DIHYDRO-1,4-BENZOXAZIN-3-ONE;7-fluoro-3,4-dihydro-2H-1,4-benzoxazin-3-one;7-fluoro-3,4-dihydro-3-oxo-2H-1,4-benzoxazine;3-Oxo-7-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine;3,4-Dihydro-7-fluoro-3-oxo-2H-1,4-benzoxazine, 7-Fluoro-4H-benzo[b][1,4]oxazin-3-one
CBNumber: CB41517828
Molecular Formula: C8H6FNO2
Formula Weight: 167.14
MOL File: 103361-99-5.mol

More

Less

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Property

Melting point:: 203-205°
Boiling point:: 327.9±42.0 °C(Predicted)
Density: 1.347
storage temp.: Sealed in dry,Room Temperature
pka: 11.56±0.20(Predicted)
Appearance: Light brown to brown Solid

More

Less

Safety

HazardClass: IRRITANT
HS Code: 2934999090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: F597840
Product name: 7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one
Packaging: 50mg
Price: $90
Updated: 2021/12/16

Apolloscientific

Product number: PC200146
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Packaging: 500mg
Price: $95
Updated: 2021/12/16

Matrix Scientific

Product number: 046220
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Purity: >95%
Packaging: 500mg
Price: $125
Updated: 2021/12/16

Apolloscientific

Product number: PC200146
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Packaging: 1g
Price: $144
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-3-2F
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Packaging: 500mg
Price: $152
Updated: 2021/12/16

More

Less

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Chemical Properties,Usage,Production

Synthesis

103362-07-8

103361-99-5

Ethyl 2-nitro-5-fluorophenoxyacetate (50 mmol) was added to 50 mL of glacial acetic acid. It was heated to reflux under stirring conditions and iron powder (100 mmol) was added in three batches. After addition, the reaction was continued to reflux for 3 hours. Upon completion of the reaction, the filtrate was filtered through a diatomaceous earth pad while hot to remove the iron powder. The filtrate was cooled to room temperature and then slowly poured into 200 mL of water with vigorous stirring for 30 minutes. The precipitated solid was collected by filtration, washed with deionized water and dried under vacuum to give 7.18 g of white solid product 7-fluoro-2H-1,4-benzoxazin-3(4H)-one in 86% yield.

References

[1] Patent: CN108727367, 2018, A. Location in patent: Paragraph 0138; 0142; 0143
[2] Patent: WO2014/122674, 2014, A1. Location in patent: Paragraph 00065
[3] Patent: WO2011/151361, 2011, A1. Location in patent: Page/Page column 40-41
[4] Patent: WO2013/153539, 2013, A1. Location in patent: Page/Page column 47
[5] Journal of Agricultural and Food Chemistry, 2017, vol. 65, # 26, p. 5278 - 5286

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Suppliers

China 53 Germany 1 India 1 United Kingdom 1 United States 9 Global 65

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Atop-Pharma (Shanghai) Technology Co., Ltd.

Tel: +86 (21) 5196-9732
Fax: +86 (21) 5196-9733
Country: China
ProdList: 996
Advantage: 57

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Shanghai Raise Chemical Technology Co.,Ltd

Tel: 15026594951
Fax: 0556-5030632
Email: rs@raise-chem.com
Country: China
ProdList: 4454
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Hotechem Shanghai Co., Ltd.,

Tel: 021-34621078 13120882795
Fax: 021-34622517
Email: 465106944@qq.com
Country: China
ProdList: 857
Advantage: 56

Zhengzhou Guancheng Laboratory equipment Sales

Tel: 0371-88888888 272369594
Fax: QQ:272369594
Email: 2723695949@qq.com
Country: China
ProdList: 4958
Advantage: 50

103361-99-5, 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONERelated Search:

7-FLUORO-1-H-BENZO[D][1,3]OXAZINE-2,4-DIONE 2H-1,4-BENZOXAZIN-3(4H)-ONE 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE FLUMIOXAZIN

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE

7-FLUORO-2,4-DIHYDRO-1,4-BENZOXAZIN-3-ONE

7-FLUORO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE

3-Oxo-7-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine

7-Fluoro-4H-benzo[1,4]oxazin-3-one

7-fluoro-3,4-dihydro-2H-1,4-benzoxazin-3-one

3,4-Dihydro-7-fluoro-3-oxo-2H-1,4-benzoxazine, 7-Fluoro-4H-benzo[b][1,4]oxazin-3-one

7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H)

7-fluoro-3,4-dihydro-3-oxo-2H-1,4-benzoxazine

2H-1,4-Benzoxazin-3(4H)-one, 7-fluoro-

103361-99-5

Heterocycles