ChemicalBook > CAS DataBase List > 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE

Product Name: 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE
CAS No.: 103361-99-5
Chemical Name: 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE
Synonyms: 7-Fluoro-4H-benzo[1,4]oxazin-3-one;7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE;7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H);2H-1,4-Benzoxazin-3(4H)-one, 7-fluoro-;7-FLUORO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE;7-FLUORO-2,4-DIHYDRO-1,4-BENZOXAZIN-3-ONE;7-fluoro-3,4-dihydro-2H-1,4-benzoxazin-3-one;7-fluoro-3,4-dihydro-3-oxo-2H-1,4-benzoxazine;3-Oxo-7-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine;3,4-Dihydro-7-fluoro-3-oxo-2H-1,4-benzoxazine, 7-Fluoro-4H-benzo[b][1,4]oxazin-3-one
CBNumber: CB41517828
Molecular Formula: C8H6FNO2
Formula Weight: 167.14
MOL File: 103361-99-5.mol

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7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Property

Melting point:: 203-205°
Boiling point:: 327.9±42.0 °C(Predicted)
Density: 1.347
storage temp.: Sealed in dry,Room Temperature
pka: 11.56±0.20(Predicted)
Appearance: Light brown to brown Solid

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Safety

HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F597840
Product name: 7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one
Packaging: 50mg
Price: $90
Updated: 2021/12/16

Apolloscientific

Product number: PC200146
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Packaging: 500mg
Price: $95
Updated: 2021/12/16

Matrix Scientific

Product number: 046220
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Purity: >95%
Packaging: 500mg
Price: $125
Updated: 2021/12/16

Apolloscientific

Product number: PC200146
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Packaging: 1g
Price: $144
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-3-2F
Product name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
Packaging: 500mg
Price: $152
Updated: 2021/12/16

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7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Chemical Properties,Usage,Production

Synthesis

103362-07-8

103361-99-5

Ethyl 2-nitro-5-fluorophenoxyacetate (50 mmol) was added to 50 mL of glacial acetic acid. It was heated to reflux under stirring conditions and iron powder (100 mmol) was added in three batches. After addition, the reaction was continued to reflux for 3 hours. Upon completion of the reaction, the filtrate was filtered through a diatomaceous earth pad while hot to remove the iron powder. The filtrate was cooled to room temperature and then slowly poured into 200 mL of water with vigorous stirring for 30 minutes. The precipitated solid was collected by filtration, washed with deionized water and dried under vacuum to give 7.18 g of white solid product 7-fluoro-2H-1,4-benzoxazin-3(4H)-one in 86% yield.

References

[1] Patent: CN108727367, 2018, A. Location in patent: Paragraph 0138; 0142; 0143
[2] Patent: WO2014/122674, 2014, A1. Location in patent: Paragraph 00065
[3] Patent: WO2011/151361, 2011, A1. Location in patent: Page/Page column 40-41
[4] Patent: WO2013/153539, 2013, A1. Location in patent: Page/Page column 47
[5] Journal of Agricultural and Food Chemistry, 2017, vol. 65, # 26, p. 5278 - 5286

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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103361-99-5, 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONERelated Search:

7-FLUORO-1-H-BENZO[D][1,3]OXAZINE-2,4-DIONE 2H-1,4-BENZOXAZIN-3(4H)-ONE 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE FLUMIOXAZIN

7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE

7-FLUORO-2,4-DIHYDRO-1,4-BENZOXAZIN-3-ONE

7-FLUORO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE

3-Oxo-7-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine

7-Fluoro-4H-benzo[1,4]oxazin-3-one

7-fluoro-3,4-dihydro-2H-1,4-benzoxazin-3-one

3,4-Dihydro-7-fluoro-3-oxo-2H-1,4-benzoxazine, 7-Fluoro-4H-benzo[b][1,4]oxazin-3-one

7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H)

7-fluoro-3,4-dihydro-3-oxo-2H-1,4-benzoxazine

2H-1,4-Benzoxazin-3(4H)-one, 7-fluoro-

103361-99-5

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