ChemicalBook > CAS DataBase List > Ponesterone A

Ponesterone A

Product Name
Ponesterone A
CAS No.
13408-56-5
Chemical Name
Ponesterone A
Synonyms
PONASTERONE A;ponesterone A;25-DEOXYECDYSTERONE;Ponasterone A, >=98%;25-DEOXY-20-HYDROXYECDYSONE;2β,3β,14α,20r,22r-pentahydroxy-5β-cholest-7-en-6-one;2B,3B,14A,20R,22R-PENTAHYDROXY-5B-CHOLEST-7-EN-6-ONE;2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one;(20R,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7-ene-6-one;Cholest-7-en-6-one, 2,3,14,20,22-pentahydroxy-, (2β,3β,5β,22R)-
CBNumber
CB4155274
Molecular Formula
C27H44O6
Formula Weight
464.63
MOL File
13408-56-5.mol
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Ponesterone A Property

Melting point:
259-260° (dec)
alpha 
D15 +90° (methanol)
Boiling point:
640.5±55.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Methanol (Slightly, Sonicated), Pyridine (Slightly)
pka
14.13±0.70(Predicted)
form 
White to off-white powder.
color 
White to Off-White
InChIKey
PJYYBCXMCWDUAZ-JJJZTNILSA-N
CAS DataBase Reference
13408-56-5(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P3490
Product name
Ponasterone A
Purity
≥65%
Packaging
1mg
Price
$95.3
Updated
2024/03/01
Cayman Chemical
Product number
16386
Product name
Ponasterone A
Purity
≥95%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
16386
Product name
Ponasterone A
Purity
≥95%
Packaging
5mg
Price
$225
Updated
2024/03/01
Cayman Chemical
Product number
16386
Product name
Ponasterone A
Purity
≥95%
Packaging
10mg
Price
$419
Updated
2024/03/01
Cayman Chemical
Product number
16386
Product name
Ponasterone A
Purity
≥95%
Packaging
25mg
Price
$893
Updated
2024/03/01
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Ponesterone A Chemical Properties,Usage,Production

Description

Ponesterone A, a steroidal compound, falls under the category of ecdysone and can be found in various sources throughout nature. It was first isolated from insect plants by Nakanishi and Horm in 1966. Compared to β-ecdysone, Ponesterone proves to be 3-100 times more potent in specific neurosensory systems.

Uses

Ponasterone A has been used to induce the expression of human huntingtin (HTT).

Definition

ChEBI: Ponasterone A is a 2beta-hydroxy steroid, a 3beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 20-hydroxy steroid, a 22-hydroxy steroid, a 6-oxo steroid and a phytoecdysteroid.

Biochem/physiol Actions

Ponasterone A is an analogue of ecdysone. It induced death of non-adapted insects may be related to PoA regulating different set of genes when compared to 20E.

storage

+4°C

Ponesterone A Preparation Products And Raw materials

Raw materials

Preparation Products

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Ponesterone A Suppliers

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View Lastest Price from Ponesterone A manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
PONASTERONE A 13408-56-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-22

13408-56-5, Ponesterone ARelated Search:

Ponasterone C Ponasterone B PONASTERONE A, [24,25,26,27-3H(N)],PONASTERONE A, [24,25,26,27-3H(H)] Hydroxyecdysone inokosterone turkesterone MAKISTERONE A Ponesterone A AKOS NCG1-0024

  • 2β,3β,14α,20r,22r-pentahydroxy-5β-cholest-7-en-6-one
  • PONASTERONE A
  • 2B,3B,14A,20R,22R-PENTAHYDROXY-5B-CHOLEST-7-EN-6-ONE
  • 2BETA, 3BETA, 14ALPHA, 20R,22R-PENTAHYDROXY-5BETA-CHOLEST-7-EN-6-ONE
  • 25-DEOXY-20-HYDROXYECDYSONE
  • 25-DEOXYECDYSTERONE
  • Ponasterone A, >=98%
  • 25-Deoxy-20-hydroxyecdysone, 25-Deoxyecdysterone, 2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one
  • (20R,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7-ene-6-one
  • (20R,22R)-2β,3β,14α,20β,22α-Pentahydroxy-5β-cholesta-7-ene-6-one
  • Cholest-7-en-6-one, 2,3,14,20,22-pentahydroxy-, (2β,3β,5β,22R)-
  • (2S,3R,5R,9R,10R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
  • gene,ecdysone,ecdysteroid,25-Deoxyecdysterone,expression,inhibit,Ponasterone A,Inhibitor
  • ponesterone A
  • 2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one
  • 13408-56-5
  • C27H44O6
  • Hormones
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  • Cytokines, Growth Factors and Hormones
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Steroid Hormones
  • Steroids