Ataciguat

Product Name: Ataciguat
CAS No.: 254877-67-3
Chemical Name: Ataciguat
Synonyms: HMR 1766;HMR-1766A;Ataciguat;Ataciguat (HMR-1766;Ataciguat, 10 mM in DMSO;5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide;5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide;Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-;cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
CBNumber: CB41565384
Molecular Formula: C21H19Cl2N3O6S3
Formula Weight: 576.5
MOL File: 254877-67-3.mol

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Ataciguat Property

Density: 1.613±0.06 g/cm3(Predicted)
solubility: DMF: 1 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
form: A crystalline solid
pka: 5.70±0.50(Predicted)
color: White to off-white
InChIKey: PQHLRGARXNPFCF-UHFFFAOYSA-N
SMILES: C(NC1=CC=C(S(N2CCOCC2)(=O)=O)C=C1)(=O)C1=CC(Cl)=CC=C1NS(C1SC(Cl)=CC=1)(=O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2598
Product name: Ataciguat
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $115
Updated: 2026/03/19

Sigma-Aldrich

Product number: SML2598
Product name: Ataciguat
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $433
Updated: 2025/07/31

Cayman Chemical

Product number: 16371
Product name: Ataciguat
Purity: ≥95%
Packaging: 1mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 16371
Product name: Ataciguat
Purity: ≥95%
Packaging: 5mg
Price: $356
Updated: 2024/03/01

Cayman Chemical

Product number: 16371
Product name: Ataciguat
Purity: ≥95%
Packaging: 10mg
Price: $632
Updated: 2024/03/01

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Ataciguat Chemical Properties,Usage,Production

Uses

Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, belongs to a new structural class of sGC activators capable of activating the oxidized form of sGC. Ataciguat has been shown to improve endothelial function and to reduce platelet activation in exptl. diabetes. Chronic regular treatment with sGC activators such as ataciguat could therefore eventually constitute an effective therapy targeting deficient NO/cGMP signaling in hypertension, peripheral and coronary artery disease, heart failure, thrombosis and erectile dysfunction.

Ataciguat Preparation Products And Raw materials

Raw materials

Preparation Products

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Ataciguat Suppliers

Canada 1 China 61 India 1 United States 6 USA 1 Global 70

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

ShangHai KenEn Chemical Technology Co., Ltd.

Tel: 13120367189
Fax: 021-50315529
Email: mychess007@163.com
Country: China
ProdList: 1994
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4810
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9426
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

254877-67-3, AtaciguatRelated Search:

Ataciguat

5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide

Ataciguat

HMR 1766

Ataciguat (HMR-1766

Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-

cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate

5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide

Ataciguat, 10 mM in DMSO

HMR-1766A

254877-67-3

C21H19Cl2N3O6S3

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds

Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds