ChemicalBook > CAS DataBase List > Ataciguat

Ataciguat

Product Name
Ataciguat
CAS No.
254877-67-3
Chemical Name
Ataciguat
Synonyms
HMR 1766;Ataciguat;Ataciguat (HMR-1766;5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide;5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide;Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-;cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
CBNumber
CB41565384
Molecular Formula
C21H19Cl2N3O6S3
Formula Weight
576.5
MOL File
254877-67-3.mol
More
Less

Ataciguat Property

Density 
1.613±0.06 g/cm3(Predicted)
solubility 
DMF: 1 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
form 
A crystalline solid
pka
5.70±0.50(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
16371
Product name
Ataciguat
Purity
≥95%
Packaging
1mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
16371
Product name
Ataciguat
Purity
≥95%
Packaging
5mg
Price
$356
Updated
2024/03/01
Cayman Chemical
Product number
16371
Product name
Ataciguat
Purity
≥95%
Packaging
10mg
Price
$632
Updated
2024/03/01
TRC
Product number
A790040
Product name
Ataciguat
Packaging
5mg
Price
$290
Updated
2021/12/16
ApexBio Technology
Product number
C4216
Product name
Ataciguat
Packaging
10mg
Price
$720
Updated
2021/12/16
More
Less

Ataciguat Chemical Properties,Usage,Production

Uses

Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, belongs to a new structural class of sGC activators capable of activating the oxidized form of sGC. Ataciguat has been shown to improve endothelial function and to reduce platelet activation in exptl. diabetes. Chronic regular treatment with sGC activators such as ataciguat could therefore eventually constitute an effective therapy targeting deficient NO/cGMP signaling in hypertension, peripheral and coronary artery disease, heart failure, thrombosis and erectile dysfunction.

Ataciguat Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ataciguat Suppliers

ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58
ShangHai KenEn Chemical Technology Co., Ltd.
Tel
13120367189
Fax
021-50315529
Email
mychess007@163.com
Country
China
ProdList
1994
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9254
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2989
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9779
Advantage
58

254877-67-3, AtaciguatRelated Search:


  • 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide
  • Ataciguat
  • HMR 1766
  • Ataciguat (HMR-1766
  • Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-
  • cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
  • 5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide
  • 254877-67-3
  • C21H19Cl2N3O6S3
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds