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Ataciguat

Product Name
Ataciguat
CAS No.
254877-67-3
Chemical Name
Ataciguat
Synonyms
HMR 1766;Ataciguat;Ataciguat (HMR-1766;5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide;5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide;Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-;cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
CBNumber
CB41565384
Molecular Formula
C21H19Cl2N3O6S3
Formula Weight
576.5
MOL File
254877-67-3.mol
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Ataciguat Property

Density 
1.613±0.06 g/cm3(Predicted)
solubility 
DMF: 1 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
form 
A crystalline solid
pka
5.70±0.50(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16371
Product name
Ataciguat
Purity
≥95%
Packaging
1mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
16371
Product name
Ataciguat
Purity
≥95%
Packaging
5mg
Price
$356
Updated
2024/03/01
Cayman Chemical
Product number
16371
Product name
Ataciguat
Purity
≥95%
Packaging
10mg
Price
$632
Updated
2024/03/01
TRC
Product number
A790040
Product name
Ataciguat
Packaging
5mg
Price
$290
Updated
2021/12/16
ApexBio Technology
Product number
C4216
Product name
Ataciguat
Packaging
10mg
Price
$720
Updated
2021/12/16
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Ataciguat Chemical Properties,Usage,Production

Uses

Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, belongs to a new structural class of sGC activators capable of activating the oxidized form of sGC. Ataciguat has been shown to improve endothelial function and to reduce platelet activation in exptl. diabetes. Chronic regular treatment with sGC activators such as ataciguat could therefore eventually constitute an effective therapy targeting deficient NO/cGMP signaling in hypertension, peripheral and coronary artery disease, heart failure, thrombosis and erectile dysfunction.

Ataciguat Preparation Products And Raw materials

Raw materials

Preparation Products

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Ataciguat Suppliers

ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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J & K SCIENTIFIC LTD.
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254877-67-3, AtaciguatRelated Search:


  • 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide
  • Ataciguat
  • HMR 1766
  • Ataciguat (HMR-1766
  • Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-
  • cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
  • 5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide
  • 254877-67-3
  • C21H19Cl2N3O6S3
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds