SPIROXATRINE

Product Name: SPIROXATRINE
CAS No.: 1054-88-2
Chemical Name: SPIROXATRINE
Synonyms: R 5188;SPIROXATRINE;Spiroxatrine (R 5188);SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5;8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-;8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE;R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one
CBNumber: CB4157162
Molecular Formula: C22H25N3O3
Formula Weight: 379.45
MOL File: 1054-88-2.mol

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SPIROXATRINE Property

Melting point:: 215.8-218.0 °C
Boiling point:: 602.8±55.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Store at RT
solubility: 0.1 M HCl: moderately soluble
form: powder
pka: 15.03±0.20(Predicted)
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 0631
Product name: Spiroxatrine
Packaging: 10
Price: $145
Updated: 2021/12/16

Tocris

Product number: 0631
Product name: Spiroxatrine
Packaging: 50
Price: $593
Updated: 2021/12/16

TRC

Product number: S683503
Product name: Spiroxatrine(R5188)
Packaging: 10mg
Price: $105
Updated: 2021/12/16

Usbiological

Product number: 466452
Product name: Spiroxatrine
Packaging: 10mg
Price: $382
Updated: 2021/12/16

Usbiological

Product number: 256729
Product name: Spiroxatrine
Packaging: 10mg
Price: $389
Updated: 2021/12/16

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SPIROXATRINE Chemical Properties,Usage,Production

Uses

Spiroxatrine (R 5188) is a SR-1A antagonist.

Definition

ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines.

Biological Activity

5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.

SPIROXATRINE Preparation Products And Raw materials

Raw materials

Preparation Products

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SPIROXATRINE Suppliers

China 25 Germany 2 Switzerland 3 United Kingdom 2 United States 9 USA 1 Global 42

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-81148696 +86-15536356810
Email: 1022@dideu.com
Country: China
ProdList: 3882
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44806
Advantage: 58

Changzhou Furuisi Biotechnology Co., Ltd

Tel: 0519-85524369
Email: 3477467573@qq.com
Country: China
ProdList: 8617
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai Tachizaki Biomedical Research Center

Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Country: China
ProdList: 2611
Advantage: 58

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View Lastest Price from SPIROXATRINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: SPIROXATRINE 1054-88-2
Price: US $0.10/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10
Release date: 2024-07-07

1054-88-2, SPIROXATRINERelated Search:

2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE Piperoxan 4-(DIETHYLAMINO)BUTYLAMINE 2-Isopropoxyphenol 3-PIPERIDINO-1,2-PROPANEDIOL N-(1-METHYLPIPERIDIN-4-YL)ANILINE SPIROXATRINE Hexahydroisonicotinamide (1-Methyl-4-piperidinyl)methanamine 2-(2-Methoxyphenoxy)ethylamine 1,3-Propanediamine,N3,N3-dimethyl-1-phenyl- N-(2-Hydroxyethyl)-1,4-butanediamine 1-METHYLPIPERIDINE-4-CARBALDEHYDE 1,4-Benzodioxan 2-methyl-1,4-diaminobutane 1,4-BENZODIOXAN-2-METHYLAMINE, N-METHYL- CHEMBRDG-BB 4009655 1-[1-(2-METHOXYETHYL)PIPERIDIN-4-YL]METHANAMINE

SPIROXATRINE

R 5188

(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE

8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE

SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5

R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one

Spiroxatrine (R 5188)

8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-

8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

1054-88-2

Serotonin receptor