3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER
- Product Name
- 3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER
- CAS No.
- 121912-29-6
- Chemical Name
- 3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER
- Synonyms
- Ethyl 1-(4-pyridinyl)-4-piperidinecarboxylate;Ethyl 1-(4-pyridinyl)piperidine-4-carboxylate;Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate;1-pyridin-4-yl-4-piperidinecarboxylic acid ethyl ester;4-Piperidinecarboxylic acid, 1-(4-pyridinyl)-, ethyl ester;3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER
- CBNumber
- CB4164285
- Molecular Formula
- C13H18N2O2
- Formula Weight
- 234.29
- MOL File
- 121912-29-6.mol
3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER Property
- Boiling point:
- 356.4±32.0 °C(Predicted)
- Density
- 1.120±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 10.88±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 132521
- Product name
- Ethyl 1-(4-pyridinyl)piperidine-4-carboxylate
- Packaging
- 5.00g
- Price
- $1404
- Updated
- 2026/05/18
- Product number
- 132521
- Product name
- Ethyl 1-(4-pyridinyl)piperidine-4-carboxylate
- Packaging
- 10.00g
- Price
- $1800
- Updated
- 2026/05/18
- Product number
- E57076
- Product name
- Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate
- Purity
- 97%
- Packaging
- 100mg
- Price
- $80
- Updated
- 2026/05/06
- Product number
- E57076
- Product name
- Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2026/05/06
- Product number
- E57076
- Product name
- Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $960
- Updated
- 2026/05/06
3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Synthesis
64-17-5
93913-86-1
121912-29-6
Example 2 Difluorotriacetate of [1-(pyridin-4-yl)piperidin-4-yl]methyl 2-[amino(imino)methyl]-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid; Step 1 Synthesis of ethyl 1-(pyridin-4-yl)piperidin-4- carboxylate; To a 1-(pyridin-4-yl)piperidin-4-carboxylic acid (20.0 g, 97.0 mmol) ethanol (480 mL) suspension of thionyl chloride (7.1 mL, 97.0 mmol) was added dropwise and the mixture was stirred at 50°C overnight. After completion of the reaction, the solvent was removed by evaporation under reduced pressure and the resulting residue was diluted with dichloromethane, washed sequentially with 1N aqueous sodium hydroxide and saturated aqueous ammonium chloride, the organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate, which did not require further purification. Yield: 21.0 g (89.7 mmol, 93%). MS (ESI, m/z): 235 [M + H]+. 1H-NMR (CDCl3) δ: 1.26 (t, 3H), 1.72-1.86 (m, 2H), 1.97-2.05 (m, 2H), 2.49-2.58 (m, 1H), 2.93-3.02 (m , 2H), 3.82-3.02 (m, 2H). , 2H), 3.82 (dt, 2H), 4.16 (q, 2H), 6.66 (dd, 2H), 8.25 (dd, 2H).
References
[1] Patent: EP2311810, 2011, A1. Location in patent: Page/Page column 21
[2] Tetrahedron, 1988, vol. 44, # 23, p. 7095 - 7108
3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials
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