ChemicalBook > CAS DataBase List > 3-Bromo-4-fluorotoluene

3-Bromo-4-fluorotoluene

Product Name
3-Bromo-4-fluorotoluene
CAS No.
452-62-0
Chemical Name
3-Bromo-4-fluorotoluene
Synonyms
3-Bromo-4-fluorotolu;3-Bromo-4-fluotoluene;3-Bromo-4-flurotoluene;3-BROMO-4-FLUOROTOLUENE;3-broMo -4-fluorine toluene;3-Bromo-4-fluorotoluene,99%;3-Bromo-4-fluorotoluene >3-Bromo-4-fluorotoluene 99%;2-BROMO-1-FLUORO-4-METHYLBENZENE;Benzene, 2-bromo-1-fluoro-4-methyl-
CBNumber
CB4171267
Molecular Formula
C7H6BrF
Formula Weight
189.02
MOL File
452-62-0.mol
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3-Bromo-4-fluorotoluene Property

Boiling point:
169 °C/756 mmHg (lit.)
Density 
1.507 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.531(lit.)
Flash point:
164 °F
storage temp. 
Sealed in dry,Room Temperature
form 
Liquid
Specific Gravity
1.52
color 
Clear colorless to light yellow
BRN 
1680604
InChI
InChI=1S/C7H6BrF/c1-5-2-3-7(9)6(8)4-5/h2-4H,1H3
InChIKey
QLRKALMVPCQTMU-UHFFFAOYSA-N
SMILES
C1(F)=CC=C(C)C=C1Br
CAS DataBase Reference
452-62-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29039990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
337013
Product name
3-Bromo-4-fluorotoluene
Purity
99%
Packaging
5g
Price
$31.2
Updated
2023/06/20
TCI Chemical
Product number
B1945
Product name
3-Bromo-4-fluorotoluene
Purity
>98.0%(GC)
Packaging
5g
Price
$64
Updated
2025/07/31
TRC
Product number
B693478
Product name
3-Bromo-4-fluorotoluene
Packaging
1g
Price
$55
Updated
2021/12/16
TRC
Product number
B693478
Product name
3-Bromo-4-fluorotoluene
Packaging
500mg
Price
$45
Updated
2021/12/16
TRC
Product number
B693478
Product name
3-Bromo-4-fluorotoluene
Packaging
2.5g
Price
$65
Updated
2021/12/16
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3-Bromo-4-fluorotoluene Chemical Properties,Usage,Production

Chemical Properties

colorless to light yellow liqui

Uses

3-Bromo-4-fluorotoluene was employed as starting reagent in the synthesis of [4-fluoro-3-(trimethylsilyl)benzyl]guanidine. It was also employed as benzyne precursor in the synthesis of 6-methyl-1,2,3,4-tetrahydro-2,3-(benzylidenedioxy)-1,4-ethenonapthalene.

Synthesis

542-56-3

583-68-6

452-62-0

Example 4: 84 g of 2-bromo-4-methylaniline and 54.5 g of isobutyl nitrite were slowly added dropwise through two dropping funnels, respectively, to a solution of 160 g of dimethoxyethane containing 37 g of boron trifluoride and 10.3 g of hydrogen fluoride at a temperature of -5°C to 0°C (the dropping process lasted for 1 hour). After the dropwise addition, the reaction mixture was continued to be stirred at 0°C for 15 min, followed by diafiltration. The resulting crystalline diazonium salt was washed with 50 mL of pre-cooled dimethoxyethane and then dried under vacuum at room temperature. A diazonium salt product of 122.5 g was obtained in a yield of 86% of the theoretical value. The decomposition reaction was carried out according to the method of Example 6, resulting in 3-bromo-4-fluorotoluene in 92.4% yield of the theoretical value.

References

[1] Patent: US4476320, 1984, A

3-Bromo-4-fluorotoluene Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Bromo-4-fluorotoluene Suppliers

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View Lastest Price from 3-Bromo-4-fluorotoluene manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
3-Bromo-4-fluorotoluene 452-62-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10000KGS
Release date
2025-07-04
Hebei Chuanghai Biotechnology Co., Ltd
Product
3-Bromo-4-fluorotoluene 452-62-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-07
Shaanxi Dideu Medichem Co. Ltd
Product
3-Bromo-4-fluorotoluene 452-62-0
Price
US $0.00-0.00/KG
Min. Order
50mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-08

452-62-0, 3-Bromo-4-fluorotolueneRelated Search:

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