3'-Bromo-4'-fluoroacetophenone

Product Name: 3'-Bromo-4'-fluoroacetophenone
CAS No.: 1007-15-4
Chemical Name: 3'-Bromo-4'-fluoroacetophenone
Synonyms: 1-(3-bromo-4-fluorophenyl)ethan-1-one;1-(3-BROMO-4-FLUOROPHENYL)ETHANONE;3-Bromo-4-fluoroacetphenone;3-BROMO-4-FLUOROACETOPHENONE;3'-Bromo-4'-fluoroacetophone;3'-Bromo-4'-fluoroacetophenone;4-Acetyl-2-bromo-1-fluorobenzene;3'-Bromo-4'-fluoroacetophenone97%;3'-Bromo-4'-fluoroacetophenone >3- BROMO-4-FLUOROACETOPHENONE 98+%
CBNumber: CB1160958
Molecular Formula: C8H6BrFO
Formula Weight: 217.04
MOL File: 1007-15-4.mol

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3'-Bromo-4'-fluoroacetophenone Property

Melting point:: 52-57 °C(lit.)
Boiling point:: 150°C 12mm
Density: 1.5728 (rough estimate)
refractive index: 1.5450 (estimate)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
color: White to Orange to Green
BRN: 3088698
CAS DataBase Reference: 1007-15-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29147000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 339679
Product name: 3′-Bromo-4′-fluoroacetophenone
Purity: 96%
Packaging: 25g
Price: $349
Updated: 2023/06/20

TCI Chemical

Product number: B2014
Product name: 3'-Bromo-4'-fluoroacetophenone
Purity: >96.0%(GC)
Packaging: 5g
Price: $82
Updated: 2025/07/31

TCI Chemical

Product number: B2014
Product name: 3'-Bromo-4'-fluoroacetophenone
Purity: >96.0%(GC)
Packaging: 25g
Price: $326
Updated: 2025/07/31

TRC

Product number: B691883
Product name: 3''-Bromo-4''-fluoroacetophone
Packaging: 1g
Price: $55
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK178609
Product name: 3'-Bromo-4'-fluoroacetophenone
Purity: 97%
Packaging: 5g
Price: $71
Updated: 2021/12/16

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3'-Bromo-4'-fluoroacetophenone Chemical Properties,Usage,Production

Chemical Properties

White to yellowish low melting soli

General Description

3′-Bromo-4′-fluoroacetophenone is also referred as 3-bromo-4-fluoro-acetophenone. Palladium-catalyzed amination of 3-bromo-4-fluoro-acetophenone has been reported.

Synthesis

403-42-9

176548-69-9

1007-15-4

Example A5: Synthesis of 1-(3,5-dibromo-4-fluorophenyl)ethan-1-one and 1-(3-bromo-4-fluorophenyl)ethan-1-one 69 g (0.5 mol) of 4-fluoroacetophenone was slowly added dropwise to 200.0 g (1.5 mol) of finely powdered aluminum and heated to 70 °C with stirring. The reaction temperature was maintained at 75-80 °C for 20 min, followed by the slow addition of 184 g (1.15 mol) of bromine at the same temperature over a period of 2.5 hours. After completion of the reaction, the mixture was heated to 90 °C and maintained for 3 hours. After cooling, decolorization was carried out and then the mixture was partitioned between water and tert-butyl methyl ether. The organic phase was separated to give 130 g of brownish black oil. The oily substance was separated by column chromatography on toluene, using toluene as eluent, to give a two-part product: a) 41.2 g (28% of theoretical yield) of colorless crystals with a melting point of 59-62 °C and an Rf = 0.53 (toluene). Identified by spectral analysis as 1-(3,5-dibromo-4-fluorophenyl)-1-ethanone. IR (KBr): 1685 (C=O) cm?1; MS: M? = 294/296/298 (Br?). b) 41.2 g (28% of the theoretical yield) colorless crystals, melting point 59-62 °C, Rf = 0.53 (toluene). b) 46.0 g (42% of theoretical yield) colorless crystals, melting point 52-55 °C, Rf = 0.41 (toluene). Identified by spectral analysis as 1-(3-bromo-4-fluorophenyl)-1-ethanone. IR (KBr): 1682 (C=O) cm?1; MS: M? = 216/218 (Br). c) 46.0 g (42% of theoretical yield) colorless crystals, melting point 52-55 °C, Rf = 0.41 (toluene).

References

[1] Patent: US7230001, 2007, B1. Location in patent: Page/Page column 67-68

3'-Bromo-4'-fluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-Bromo-4'-fluoroacetophenone Suppliers

Americas 1 Belgium 3 China 167 Europe 1 France 2 Germany 4 India 10 Italy 1 Japan 5 Slovakia 1 Switzerland 3 Ukraine 2 United Kingdom 16 United States 53 Global 269

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View Lastest Price from 3'-Bromo-4'-fluoroacetophenone manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3'-Bromo-4'-fluoroacetophenone 1007-15-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-09

Shaanxi Dideu Medichem Co. Ltd

Product: 3'-Bromo-4'-fluoroacetophenone 1007-15-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000KG
Release date: 2024-07-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3"-Bromo-4"-fluoroacetophenone 1007-15-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

1007-15-4, 3'-Bromo-4'-fluoroacetophenoneRelated Search:

4'-Bromoacetophenone Bromocriptine mesylate PIPERACETAZINE (250 MG) Florfenicol 2-Bromoacetophenone 2,4-Dinitrofluorobenzene Bromine 3'-Bromo-2'-Fluoroacetophenone ALPHA-BROMO-3-FLUOROACETOPHENONE,2-BROMO-3'-FLUOROACETOPHENONE 3'-BROMO-4'-FLUOROPROPIOPHENONE 2'-Bromo-4'-fluoroacetophenone97%,2'-Bromo-4'-fluoroacetophenone 97% 2-Bromo-4'-fluoroacetophenone 2'-BROMO-5'-FLUOROACETOPHENONE 2-BROMO-2'-FLUOROACETOPHENONE 4-Fluoroacetophenone 1-(4-Bromo-2-fluorophenyl)ethanone 2,3'-DIBROMO-4'-FLUOROACETOPHENONE, 97% 3-(3'-BROMO-4'-FLUOROPHENYL)-3-OXOPROPANENITRILE

3-BROMO-4-FLUOROACETOPHENONE

1-(3-bromo-4-fluorophenyl)ethan-1-one

1-(3-BROMO-4-FLUOROPHENYL)ETHANONE

3- BROMO-4-FLUOROACETOPHENONE 98+%

3'-Bromo-4'-fluoroacetophenone97%

Ethanone, 1-(3-bromo-4-fluorophenyl)-

3-Bromo-4-fluorophenyl(methyl) ketone

3'-Bromo-4'-fluoroacetophone

4-Acetyl-2-bromo-1-fluorobenzene

3'-Bromo-4'-fluoroacetophenone &gt

3'-Bromo-4'-fluoroacetophenone

3′-Bromo-4′-fluoroacetophenone, CAS 1007-15-4

3-Bromo-4-fluoroacetphenone

1007-15-4

BrC6H3FCOCH3

ARYL HALIDE

Building Blocks

C7 to C8

Carbonyl Compounds

Organic Building Blocks

Ketones

Aryl Fluorinated Building Blocks

Building Blocks

C7 to C8

C7-C8

Carbonyl Compounds

Chemical Synthesis

Fluorinated Building Blocks

Organic Building Blocks

Organic Fluorinated Building Blocks

Other Fluorinated Organic Building Blocks

Fluorine series

C7 to C8

Carbonyl Compounds

Ketones

Adehydes, Acetals & Ketones

Bromine Compounds

Fluorine Compounds

Aromatic Halides (substituted)