ChemicalBook > CAS DataBase List > 4-Fluoroacetophenone

4-Fluoroacetophenone

Product Name
4-Fluoroacetophenone
CAS No.
403-42-9
Chemical Name
4-Fluoroacetophenone
Synonyms
1-(4-Fluorophenyl)ethan-1-one;1-(4-FLUOROPHENYL)ETHANONE;4-Fluoracetophenon;P-FLUOROACETOPHENONE;4'-FLUOROACETOPHENONE;p-Fluoro;AKOS BBS-00003234;4-FLUOROCETOPHENONE;Fluoroacetophenone3;4-FLUOROACETOPHENONE
CBNumber
CB6419110
Molecular Formula
C8H7FO
Formula Weight
138.14
MOL File
403-42-9.mol
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4-Fluoroacetophenone Property

Melting point:
4 °C
Boiling point:
77-78 °C10 mm Hg(lit.)
Density 
1.143 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.511(lit.)
Flash point:
160 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
form 
Liquid
Specific Gravity
1.138
color 
Clear colorless to slightly yellow
BRN 
386013
InChIKey
ZDPAWHACYDRYIW-UHFFFAOYSA-N
CAS DataBase Reference
403-42-9(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(4-fluorophenyl)-(403-42-9)
EPA Substance Registry System
4'-Fluoroacetophenone (403-42-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-23
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F3207
Product name
4′-Fluoroacetophenone
Purity
99%
Packaging
25g
Price
$54.4
Updated
2024/03/01
Sigma-Aldrich
Product number
F3207
Product name
4′-Fluoroacetophenone
Purity
99%
Packaging
100g
Price
$94.6
Updated
2024/03/01
TCI Chemical
Product number
F0261
Product name
4'-Fluoroacetophenone
Purity
>98.0%(GC)
Packaging
25g
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
F0261
Product name
4'-Fluoroacetophenone
Purity
>98.0%(GC)
Packaging
500g
Price
$486
Updated
2024/03/01
Alfa Aesar
Product number
A13950
Product name
4'-Fluoroacetophenone, 99%
Packaging
25g
Price
$32.8
Updated
2024/03/01
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4-Fluoroacetophenone Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

4-Fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Uses

4’-Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.

Uses

4’Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.

Synthesis


General procedure: Oximes (1.0 mmol), Amberlyst-15 (0.02 g), FPA53-NO2(0.02 g), and solvent (1.5 mL) were introduced into a 25-cm-high, 90-mL autoclave with a glass tube inside equipped with magnetic stirrer (Scheme 2). Then the autoclave was charged with oxygen to 0.1 MPa. The reaction mixture was stirred at desirable temperature for special time. Progress of the reaction was monitored by thin-layer chromatography (TLC) or gas chromatography (GC). After the reaction, the resin (Amberlyst-15 and FPA53-NO2) was separated from the reaction mixture by filtration and extracted with 3 mL CH3CN (2 1.5 ml). The solvent was removed under reduced pressure. The residue was further purified by column chromatography on silica gel (300 mesh) with hexane/ethyl acetate to give the corresponding carbonyl compounds.

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4-Fluoroacetophenone Suppliers

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
869
Advantage
58
Weifang QianJin Fine Chemical Co., Ltd.
Tel
13031698386 18753684562
Fax
0536-8897109
Email
1577399715@qq.COM
Country
China
ProdList
1707
Advantage
55
Weifang Weimeng Chemical Co., Ltd.
Tel
0536-8790166 15105445095
Email
weimengchem@163.com
Country
China
ProdList
472
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 4-Fluoroacetophenone manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4-Fluoroacetophenone 403-42-9
Price
US $300.00/Kg/Drum
Min. Order
1KG
Purity
99% HPLC
Supply Ability
500KG/WEEK
Release date
2021-06-02
Hebei Weibang Biotechnology Co., Ltd
Product
4-Fluoroacetophenone 403-42-9
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-23
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Fluoroacetophenone 403-42-9
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20

403-42-9, 4-FluoroacetophenoneRelated Search:


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  • 403-42-9
  • C7 to C8
  • Carbonyl Compounds
  • Building Blocks
  • Organic Building Blocks
  • Ketones
  • Adehydes, Acetals & Ketones
  • Fluorine Compounds
  • C7 to C8
  • Carbonyl Compounds
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  • Organics
  • ketone