ChemicalBook > CAS DataBase List > 2-Bromoacetophenone

2-Bromoacetophenone

Product Name
2-Bromoacetophenone
CAS No.
70-11-1
Chemical Name
2-Bromoacetophenone
Synonyms
NSC 9807;Stauffer 4644;PHENACYL BROMIDE;AKOS BBS-00004003;Bromoacetylbenzene;-Bromoacetophenone;PhenacylBromide>w-Bromoacetophenone;TIMTEC-BB SBB002705;2-Bromoacetophenone
CBNumber
CB6305185
Molecular Formula
C8H7BrO
Formula Weight
199.04
MOL File
70-11-1.mol
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2-Bromoacetophenone Property

Melting point:
48-51 °C (lit.)
Boiling point:
135 °C/18 mmHg (lit.)
Density 
1.476
refractive index 
1.5700 (estimate)
Flash point:
>230 °F
storage temp. 
2-8°C
form 
Crystals or Powder
color 
White to dark green-brown
Water Solubility 
PRACTICALLY INSOLUBLE
Merck 
14,1402
BRN 
606474
Stability:
Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
InChIKey
LIGACIXOYTUXAW-UHFFFAOYSA-N
CAS DataBase Reference
70-11-1(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 2-bromo-1-phenyl-(70-11-1)
EPA Substance Registry System
Ethanone, 2-bromo-1-phenyl- (70-11-1)
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Safety

Hazard Codes 
C
Risk Statements 
34-20/21/22
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2645 6.1/PG 2
WGK Germany 
3
8-19
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29143990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H331Toxic if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
115835
Product name
2-Bromoacetophenone
Purity
98%
Packaging
5g
Price
$33.6
Updated
2021/03/22
Sigma-Aldrich
Product number
115835
Product name
2-Bromoacetophenone
Purity
98%
Packaging
100g
Price
$79.1
Updated
2021/03/22
TCI Chemical
Product number
A5508
Product name
Phenacyl Bromide [for HPLC Labeling]
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$29
Updated
2021/03/22
TCI Chemical
Product number
B0535
Product name
Phenacyl Bromide
Purity
>98.0%(GC)
Packaging
25g
Price
$56
Updated
2021/03/22
Alfa Aesar
Product number
A15576
Product name
2-Bromoacetophenone, 98%
Packaging
25g
Price
$32.3
Updated
2021/03/22
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2-Bromoacetophenone Chemical Properties,Usage,Production

Chemical Properties

Off white-grey green crystaline powder

Uses

2-Bromoacetophenone is a brominated acteophenone derivative. 2-Bromoacetophenone has been shown to completely and irreversibly inactivate human liver aldehyde dehydrogenase (EC 1.2.1.3) isoenzymes E1 and E2. 2-Bromoacetophenone and its derivatives display some inhibitory activity on neutral protein tyrosine.inhibitors

Uses

Preparation of crystalline esters from acids

Definition

ChEBI: An alpha-bromoketone that is acetophenone substituted by a bromo group at position 2.

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 5796, 1954 DOI: 10.1021/ja01651a061
Organic Syntheses, Coll. Vol. 2, p. 480, 1943
Synthetic Communications, 22, p. 1923, 1992 DOI: 10.1080/00397919208021322

General Description

A crystalline solid or a liquid with a sharp odor. Toxic by inhalation, ingestion and skin absorption. A severe eye irritant (a lachrymator). Used to make other chemicals.

Air & Water Reactions

Reacts slowly with moisture in air to form hydrogen bromide.

Reactivity Profile

2-Bromoacetophenone reacts slowly with metals causing mild corrosion.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Purification Methods

Crystallise the bromide from EtOH, MeOH or pet ether (b 80-100o). [Tanner J Org Chem 52 2142 1987, Beilstein 7 IV 649.]

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2-Bromoacetophenone Suppliers

Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
Changzhou Jiang Xing Chemical Co., Ltd.
Fax
0519-82618888
Email
hanbao@jiangxingchem.com
Country
China
ProdList
17
Advantage
58
Shijiazhuang Als Pharmaceutical Technology Co., Ltd.
Tel
0311-85150550 18932901920
Fax
0311-85150550
Email
alspharm@163.com
Country
China
ProdList
231
Advantage
58
Weifang QianJin Fine Chemical Co., Ltd.
Fax
0536-8897109
Email
1577399715@qq.com
Country
China
ProdList
1924
Advantage
55
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-85866609- ;
Fax
0573-85866609
Email
jiaxingshidy@163.com;jiaxingshidy@163.com
Country
China
ProdList
4103
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Sichuan Ruibo Technology Co., Ltd
Tel
+86-817-5586080
Fax
+86-817-5527378
Email
sales@scrbkj.com
Country
China
ProdList
42
Advantage
69
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Email
lnthhg@thflu.com
Country
China
ProdList
338
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
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View Lastest Price from 2-Bromoacetophenone manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Bromoacetophenone 70-11-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26
Hebei shuoxi biotechnology co. LTD
Product
phenacyl bromide 70-11-1
Price
US $10.00/g
Min. Order
10g
Purity
99.8%
Supply Ability
10tons
Release date
2020-04-03
Career Henan Chemical Co
Product
2-Bromoacetophenone 70-11-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-03-13

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