2-Bromoacetophenone
- Product Name
- 2-Bromoacetophenone
- CAS No.
- 70-11-1
- Chemical Name
- 2-Bromoacetophenone
- Synonyms
- 2-BROMO-1-PHENYLETHANONE;A-BROMOACETOPHENONE;1-Phenyl-2-broMoethanone;NSC 9807;Stauffer 4644;AKOS BBS-00004003;Bromoacetylbenzene;-Bromoacetophenone;PhenacylBromide>w-Bromoacetophenone
- CBNumber
- CB6305185
- Molecular Formula
- C8H7BrO
- Formula Weight
- 199.04
- MOL File
- 70-11-1.mol
2-Bromoacetophenone Property
- Melting point:
- 48-51 °C (lit.)
- Boiling point:
- 135 °C/18 mmHg (lit.)
- Density
- 1.476
- refractive index
- 1.5700 (estimate)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Crystals or Powder
- color
- White to dark green-brown
- Water Solubility
- PRACTICALLY INSOLUBLE
- Merck
- 14,1402
- BRN
- 606474
- Stability:
- Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
- InChIKey
- LIGACIXOYTUXAW-UHFFFAOYSA-N
- CAS DataBase Reference
- 70-11-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Ethanone, 2-bromo-1-phenyl-(70-11-1)
- EPA Substance Registry System
- Ethanone, 2-bromo-1-phenyl- (70-11-1)
Safety
- Hazard Codes
- C
- Risk Statements
- 34-20/21/22
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2645 6.1/PG 2
- WGK Germany
- 3
- F
- 8-19
- Hazard Note
- Corrosive
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29143990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 115835
- Product name
- 2-Bromoacetophenone
- Purity
- 98%
- Packaging
- 5g
- Price
- $39.2
- Updated
- 2024/03/01
- Product number
- 115835
- Product name
- 2-Bromoacetophenone
- Purity
- 98%
- Packaging
- 100g
- Price
- $92.5
- Updated
- 2024/03/01
- Product number
- A5508
- Product name
- Phenacyl Bromide [for HPLC Labeling]
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $31
- Updated
- 2024/03/01
- Product number
- B0535
- Product name
- Phenacyl Bromide
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $56
- Updated
- 2024/03/01
- Product number
- A15576
- Product name
- 2-Bromoacetophenone, 98%
- Packaging
- 25g
- Price
- $37.6
- Updated
- 2023/06/20
2-Bromoacetophenone Chemical Properties,Usage,Production
Chemical Properties
Off white-grey green crystaline powder
Uses
2-Bromoacetophenone is a brominated acteophenone derivative. 2-Bromoacetophenone has been shown to completely and irreversibly inactivate human liver aldehyde dehydrogenase (EC 1.2.1.3) isoenzymes E1 and E2. 2-Bromoacetophenone and its derivatives display some inhibitory activity on neutral protein tyrosine.inhibitors
Uses
It is used in preparation of crystalline esters from acids. 2-Bromoacetophenone is a complete and irreversible inactivator of human liver aldehyde dehydrogenase isoenzymes E1 and E2.
Definition
ChEBI: An alpha-bromoketone that is acetophenone substituted by a bromo group at position 2.
Synthesis Reference(s)
Journal of the American Chemical Society, 76, p. 5796, 1954 DOI: 10.1021/ja01651a061
Organic Syntheses, Coll. Vol. 2, p. 480, 1943
Synthetic Communications, 22, p. 1923, 1992 DOI: 10.1080/00397919208021322
General Description
A crystalline solid or a liquid with a sharp odor. Toxic by inhalation, ingestion and skin absorption. A severe eye irritant (a lachrymator). Used to make other chemicals.
Air & Water Reactions
Reacts slowly with moisture in air to form hydrogen bromide.
Reactivity Profile
2-Bromoacetophenone reacts slowly with metals causing mild corrosion.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Purification Methods
Crystallise the bromide from EtOH, MeOH or pet ether (b 80-100o). [Tanner J Org Chem 52 2142 1987, Beilstein 7 IV 649.]
2-Bromoacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromoacetophenone Suppliers
- Tel
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- Fax
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- nfo@matrix-fine-chemicals.com
- Country
- Switzerland
- ProdList
- 6968
- Advantage
- 58
- Tel
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- Country
- Switzerland
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View Lastest Price from 2-Bromoacetophenone manufacturers
- Product
- 2-Bromoacetophenone 70-11-1
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-10-13
- Product
- 2-Bromoacetophenone 70-11-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-11-15
- Product
- 2-Bromoacetophenone 70-11-1
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2024-08-21