3'-Bromoacetophenone

Product Name: 3'-Bromoacetophenone
CAS No.: 2142-63-4
Chemical Name: 3'-Bromoacetophenone
Synonyms: 1-(3-BROMOPHENYL)ETHAN-1-ONE;3-BROMOACETOPHENONE;1-(3-BROMOPHENYL)ETHANONE;M-BROMOACETOPHENONE;NSC 46620;M-bromophenone;AKOS BBS-00003235;3'-Bromacetophenon;3-bromoacetephenone;BROMOACETOPHENONE-3
CBNumber: CB5233225
Molecular Formula: C8H7BrO
Formula Weight: 199.04
MOL File: 2142-63-4.mol

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3'-Bromoacetophenone Property

Melting point:: 8-11 °C(lit.)
Boiling point:: 79-81 °C0.2 mm Hg
Density: 1.505 g/mL at 25 °C(lit.)
refractive index: n20/D 1.576(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
Water Solubility: Practically insoluble in water
form: Liquid
Specific Gravity: 1.498
color: Clear slightly yellow to yellow
BRN: 507599
InChI: 1S/C8H7BrO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,1H3
InChIKey: JYAQYXOVOHJRCS-UHFFFAOYSA-N
SMILES: CC(=O)c1cccc(Br)c1
CAS DataBase Reference: 2142-63-4(CAS DataBase Reference)
NIST Chemistry Reference: 3-Bromoacetophenone(2142-63-4)
EPA Substance Registry System: Ethanone, 1-(3-bromophenyl)- (2142-63-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-36/38
Safety Statements: 26-36-24/25
WGK Germany: 3
F: 8
Hazard Note: Irritant
TSCA: TSCA listed
HS Code: 29147090
Storage Class: 10 - Combustible liquids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B56358
Product name: 3′-Bromoacetophenone
Purity: ReagentPlus , 99%
Packaging: 25g
Price: $66
Updated: 2025/07/31

Sigma-Aldrich

Product number: B56358
Product name: 3′-Bromoacetophenone
Purity: ReagentPlus , 99%
Packaging: 100g
Price: $110
Updated: 2025/07/31

TCI Chemical

Product number: B0536
Product name: 3'-Bromoacetophenone
Purity: >98.0%(GC)
Packaging: 5g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: B0536
Product name: 3'-Bromoacetophenone
Purity: >98.0%(GC)
Packaging: 25g
Price: $46
Updated: 2025/07/31

TRC

Product number: B679363
Product name: 3''-Bromoacetophenone
Packaging: 1g
Price: $55
Updated: 2021/12/16

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3'-Bromoacetophenone Chemical Properties,Usage,Production

Chemical Properties

Clear colourless to light yellow liquid

Uses

3''-Bromoacetophenone is a chemical reagent used in the synthesis of chalcone derivatives as anti-cancer agents. Also used in the preparation of biphenyl pyridazinone deriatives as PDE4 inhibitors in anti-inflammatory treatments.

Synthesis

80ml of 48% hydrobromic acid, 80ml of water and 23g m-amino acetophenone, with ice brine cold to 0 ~ 5 C, and then drop under stirring by 12.2g of sodium nitrite and 30ml of water solution (under the liquid level), and maintain the reaction temperature of 0 ~ 8 C. Drops, and continue to react for 30min. will be made above the diazonium salt solution is poured into the cold CuBr hydrochloric acid solution (27.5 gCuBr + 50 ml hydrobromic acid), heated to 50 ~ 65 , stirred thoroughly for 2 ~ 3h. Separate and remove the solid material and water phase, to obtain the oily material. The oily material was washed with water until the aqueous solution was neutral. The oily material was added to water and distilled with water vapor until there were no oil droplets. Separate the oil layer, the aqueous layer was extracted with benzene, and after combining the oil layers, the benzene was first vaporized at atmospheric pressure, and then distilled at reduced pressure to collect the fraction at 117-122C (2.3 kp), to obtain the product 3'-bromoacetophenone (31.2g, content 99.6%, yield 95.2%).

3'-Bromoacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

3-Acetylphenylboronic acid 5-(3-BROMOPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID FENOPROFEN 1-(3-phenoxyphenyl)ethanone Ethyl 3-(3-bromophenyl)-1H-pyrazole-5-carboxylate ,97% 4-(3-BROMOPHENYL)-3-PYRIDINECARBOXALDEHYDE

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3'-Bromoacetophenone Suppliers

Americas 1 Belgium 4 Canada 2 China 321 Europe 3 Germany 5 India 48 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 2 United Kingdom 20 United States 54 Global 467

Shanghai Hao Yun Chemical Science Co.,Ltd.

Tel: 021-68367562 15002147577;
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Tel: 02150630626 17717886015
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
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Liaoning Tianhua Chemical Co., Ltd.

Tel: 0418-6530555 2855550
Fax: +86-418-6502885
Country: China
ProdList: 338
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View Lastest Price from 3'-Bromoacetophenone manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 3'-Bromoacetophenone 2142-63-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-18

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3'-Bromoacetophenone 2142-63-4
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Hebei Yanxi Chemical Co., Ltd.

Product: 3'-Bromoacetophenone 2142-63-4
Price: US $20.00-10.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-10-16

2142-63-4, 3'-BromoacetophenoneRelated Search:

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3′-Bromoacetophenone, CAS 2142-63-4

2142-63-4

BrC6H4COCH3

C8H7BrO

Organic Building Blocks

Ketones

Building Blocks

C7 to C8

Carbonyl Compounds

ARYL HALIDE

Building Blocks

C7 to C8

Chemical Synthesis

Ketones

Organic Building Blocks

Acetophenone series

Bromine Compounds

API intermediates

Adehydes, Acetals & Ketones

Carbonyl Compounds

Halides

Aromatic Acetophenones & Derivatives (substituted)

Benzene series

2142-63-4