5-Bromoisatin
- Product Name
- 5-Bromoisatin
- CAS No.
- 87-48-9
- Chemical Name
- 5-Bromoisatin
- Synonyms
- 5-BROMOINDOLINE-2,3-DIONE;BromoIsatin;5-bromisatin;5-BROMO-3-CHLORO-2-METHYLPYRIDINE;NSC 4980;AKOS B028934;5-BROMOISATIN;5-bromo-isati;AKOS BBS-00000997;Reaxys ID: 383760
- CBNumber
- CB1142138
- Molecular Formula
- C8H4BrNO2
- Formula Weight
- 226.03
- MOL File
- 87-48-9.mol
5-Bromoisatin Property
- Melting point:
- 247-252 °C (lit.)
- Density
- 1.7498 (rough estimate)
- refractive index
- 1.6120 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in N,N dimethylformamide.
- pka
- 8.74±0.20(Predicted)
- form
- Crystalline Powder
- color
- Orange
- BRN
- 383760
- InChIKey
- MBVCESWADCIXJN-UHFFFAOYSA-N
- CAS DataBase Reference
- 87-48-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 37/38-41
- Safety Statements
- 26-36/39-37/39-36
- RIDADR
- 2811
- WGK Germany
- 2
- RTECS
- NL7875000
- Hazard Note
- Irritant
- HS Code
- 29337900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 476994
- Product name
- 5-Bromoisatin
- Purity
- technical grade, 90%
- Packaging
- 5g
- Price
- $17.82
- Updated
- 2024/03/01
- Product number
- 476994
- Product name
- 5-Bromoisatin
- Purity
- technical grade, 90%
- Packaging
- 25g
- Price
- $106
- Updated
- 2024/03/01
- Product number
- B1566
- Product name
- 5-Bromoisatin
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $143
- Updated
- 2024/03/01
- Product number
- B1566
- Product name
- 5-Bromoisatin
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 250g
- Price
- $714
- Updated
- 2024/03/01
- Product number
- A13641
- Product name
- 5-Bromoisatin, 90+%
- Packaging
- 50g
- Price
- $67.65
- Updated
- 2024/03/01
5-Bromoisatin Chemical Properties,Usage,Production
Chemical Properties
Orange crystalline powder
Uses
5-Bromoisatin is used in the synthesis of N-derivatives of 5-bromoisatin, N-substituted pyrroles, linear polyaryleneoxindoles, 5-bromodioxindole, cinchoninic acid derivatives, 3-hydroxyoxindole, S-benzyldithiocarbazate Schiff Bases, 5-bromooxindole and Morita-Baylis-Hillman adducts of isatin derivatives. It is an indole derivative.
Definition
ChEBI: 5-Bromoisatin is a member of indoles. It has a role as an anticoronaviral agent.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 3099, 1984 DOI: 10.1016/0040-4039(84)80017-9
General Description
5-Bromoisatin is a 5-haloisatin. One of the methods reported for its synthesis is by reacting N-halosaccharins with isatin in the presence of SiO2. Its inotropic activity has been studied on rhythmically stimulated papillary muscles of guinea pigs. It is reported to exhibit analgesic and sedative properties at a dose of 0.2g/kg in mice.
Purification Methods
5-Bromoisatin forms red prisms or needles from EtOH. The N-acetate crystallises as yellow prisms from *C6H6, m 170-172o, and the N-methyl derivative forms orange-red needles from MeOH, m 172-173o. [Heller Chem Ber 53 1545 1920, Buu-Hoi Recl Trav Chim, Pays-Bas 73 197 1954, Baker etal. Tetrahedron Lett 215 1978, Beilstein 21 H 453, 21 III/IV 5009.]
5-Bromoisatin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Bromoisatin manufacturers
- Product
- 5-Bromoisatin 87-48-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.9%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18
- Product
- 5-Bromoisatin 87-48-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 5-Bromoisatin 87-48-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,100kg
- Release date
- 2019-07-04