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2-Phenylindole

Product Name
2-Phenylindole
CAS No.
948-65-2
Chemical Name
2-Phenylindole
Synonyms
2-PHENYL-1H-INDOLE;1H-Indole,2-phenyl-;NSC 15776;stabilizeri;Stabilizer I;-Phenylindole;A-PHENYLINDOL;2-PHENYLINDOLE;a-Phenylindole;2-phenyl-indol
CBNumber
CB9725557
Molecular Formula
C14H11N
Formula Weight
193.24
MOL File
948-65-2.mol
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2-Phenylindole Property

Melting point:
188-190 °C (lit.)
Boiling point:
250 °C/10 mmHg (lit.)
Density 
1.1061 (rough estimate)
refractive index 
1.5850 (estimate)
Flash point:
250°C/10mm
storage temp. 
Sealed in dry,Room Temperature
solubility 
almost transparency in Methanol
form 
Powder
pka
16.80±0.30(Predicted)
color 
Off-white to beige or slightly green
CAS DataBase Reference
948-65-2(CAS DataBase Reference)
NIST Chemistry Reference
1H-Indole, 2-phenyl-(948-65-2)
EPA Substance Registry System
1H-Indole, 2-phenyl- (948-65-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
WGK Germany 
3
RTECS 
NM1272500
TSCA 
Yes
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P26600
Product name
2-Phenylindole
Purity
technical grade, 95%
Packaging
100g
Price
$23.92
Updated
2024/03/01
Sigma-Aldrich
Product number
P26600
Product name
2-Phenylindole
Purity
technical grade, 95%
Packaging
5g
Price
$36.4
Updated
2024/03/01
TCI Chemical
Product number
P0188
Product name
2-Phenylindole
Purity
>98.0%(GC)
Packaging
25g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
P0188
Product name
2-Phenylindole
Purity
>98.0%(GC)
Packaging
250g
Price
$78
Updated
2024/03/01
Alfa Aesar
Product number
B23674
Product name
2-Phenylindole, 95%
Packaging
50g
Price
$27.65
Updated
2024/03/01
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2-Phenylindole Chemical Properties,Usage,Production

Chemical Properties

off-white to beige or slightly green powder

Uses

Reactant for preparation of: • ;Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Organic light emitting diodes (OLEDs)3• ;Anti inflammatory agents4• ;Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors5• ;Agents for cancer and malaria therapy6• ;Antifungal and antibacterial agents7• ;Fluorescent probes8Reactant in:• ;Difluorohydroxylation reactions†• ;Mannich-type reactions†

Uses

Phenylindole is a stabilizer in PVC-plastic products (α-phenylindole).

Uses

Reactant for preparation of:

  • Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition
  • Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Organic light emitting diodes (OLEDs)
  • Anti inflammatory agents
  • Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors
  • Agents for cancer and malaria therapy
  • Antifungal and antibacterial agents
  • Fluorescent probes

Reactant in:
  • Difluorohydroxylation reactions?
  • Mannich-type reactions?

Preparation

2-phenylindole is prepared by condensing phenylhydrazine and acetophenone, and then closing the ring in the presence of zinc chloride. or it can be prepared by heating bromoacetophenone with excess aniline, or heating N-(2-methylphenyl)benzamide and sodium ethoxide at 360-380℃ in isolation from air.

Definition

ChEBI: 2-phenyl-1H-indole is a phenylindole.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 1459, 1992 DOI: 10.1016/S0040-4039(00)91646-0
Journal of Heterocyclic Chemistry, 29, p. 1085, 1992 DOI: 10.1002/jhet.5570290509

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2-Phenylindole Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
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62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
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View Lastest Price from 2-Phenylindole manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Phenylindole 948-65-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Phenylindole 948-65-2
Price
US $5.00-2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23
Hebei Weibang Biotechnology Co., Ltd
Product
2-Phenylindole 948-65-2
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2021-11-01

948-65-2, 2-PhenylindoleRelated Search:


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