ChemicalBook > CAS DataBase List > 2-Phenylindole
2-Phenylindole
- Product Name
- 2-Phenylindole
- CAS No.
- 948-65-2
- Chemical Name
- 2-Phenylindole
- Synonyms
- 2-PHENYL-1H-INDOLE;1H-Indole,2-phenyl-;NSC 15776;stabilizeri;Stabilizer I;-Phenylindole;A-PHENYLINDOL;2-PHENYLINDOLE;a-Phenylindole;2-phenyl-indol
- CBNumber
- CB9725557
- Molecular Formula
- C14H11N
- Formula Weight
- 193.24
- MOL File
- 948-65-2.mol
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2-Phenylindole Property
- Melting point:
- 188-190 °C (lit.)
- Boiling point:
- 250 °C/10 mmHg (lit.)
- Density
- 1.1061 (rough estimate)
- refractive index
- 1.5850 (estimate)
- Flash point:
- 250°C/10mm
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- almost transparency in Methanol
- form
- Powder
- pka
- 16.80±0.30(Predicted)
- color
- Off-white to beige or slightly green
- CAS DataBase Reference
- 948-65-2(CAS DataBase Reference)
- NIST Chemistry Reference
- 1H-Indole, 2-phenyl-(948-65-2)
- EPA Substance Registry System
- 1H-Indole, 2-phenyl- (948-65-2)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P26600
- Product name
- 2-Phenylindole
- Purity
- technical grade, 95%
- Packaging
- 100g
- Price
- $23.92
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P26600
- Product name
- 2-Phenylindole
- Purity
- technical grade, 95%
- Packaging
- 5g
- Price
- $36.4
- Updated
- 2024/03/01
TCI Chemical
- Product number
- P0188
- Product name
- 2-Phenylindole
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $27
- Updated
- 2024/03/01
TCI Chemical
- Product number
- P0188
- Product name
- 2-Phenylindole
- Purity
- >98.0%(GC)
- Packaging
- 250g
- Price
- $78
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- B23674
- Product name
- 2-Phenylindole, 95%
- Packaging
- 50g
- Price
- $27.65
- Updated
- 2024/03/01
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2-Phenylindole Chemical Properties,Usage,Production
Chemical Properties
off-white to beige or slightly green powder
Uses
Reactant for preparation of: • ;Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Organic light emitting diodes (OLEDs)3• ;Anti inflammatory agents4• ;Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors5• ;Agents for cancer and malaria therapy6• ;Antifungal and antibacterial agents7• ;Fluorescent probes8Reactant in:• ;Difluorohydroxylation reactions†• ;Mannich-type reactions†
Uses
Phenylindole is a stabilizer in PVC-plastic products (α-phenylindole).
Uses
Reactant for preparation of:
- Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Organic light emitting diodes (OLEDs)
- Anti inflammatory agents
- Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors
- Agents for cancer and malaria therapy
- Antifungal and antibacterial agents
- Fluorescent probes
Reactant in:
- Difluorohydroxylation reactions?
- Mannich-type reactions?
Preparation
2-phenylindole is prepared by condensing phenylhydrazine and acetophenone, and then closing the ring in the presence of zinc chloride. or it can be prepared by heating bromoacetophenone with excess aniline, or heating N-(2-methylphenyl)benzamide and sodium ethoxide at 360-380℃ in isolation from air.
Definition
ChEBI: 2-phenyl-1H-indole is a phenylindole.
Synthesis Reference(s)
Tetrahedron Letters, 33, p. 1459, 1992 DOI: 10.1016/S0040-4039(00)91646-0
Journal of Heterocyclic Chemistry, 29, p. 1085, 1992 DOI: 10.1002/jhet.5570290509
2-Phenylindole Preparation Products And Raw materials
Raw materials
Ethanol
Biphenyl
Acetone
Acetophenone
2-Bromoacetophenone
Polyphosphoric acid
Benzamide
Acetic acid
Phenylhydrazine
Preparation Products
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View Lastest Price from 2-Phenylindole manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 2-Phenylindole 948-65-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-24
Hebei Mojin Biotechnology Co., Ltd
- Product
- 2-Phenylindole 948-65-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-18
Hebei Guanlang Biotechnology Co,.LTD
- Product
- 2-Phenylindole 948-65-2
- Price
- US $5.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-02-21
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