3'-Bromo-4'-fluoroacetophenone
- Product Name
- 3'-Bromo-4'-fluoroacetophenone
- CAS No.
- 1007-15-4
- Chemical Name
- 3'-Bromo-4'-fluoroacetophenone
- Synonyms
- 1-(3-bromo-4-fluorophenyl)ethan-1-one;1-(3-BROMO-4-FLUOROPHENYL)ETHANONE;3-Bromo-4-fluoroacetphenone;3-BROMO-4-FLUOROACETOPHENONE;3'-Bromo-4'-fluoroacetophone;3'-Bromo-4'-fluoroacetophenone;4-Acetyl-2-bromo-1-fluorobenzene;3'-Bromo-4'-fluoroacetophenone97%;3'-Bromo-4'-fluoroacetophenone >3- BROMO-4-FLUOROACETOPHENONE 98+%
- CBNumber
- CB1160958
- Molecular Formula
- C8H6BrFO
- Formula Weight
- 217.04
- MOL File
- 1007-15-4.mol
3'-Bromo-4'-fluoroacetophenone Property
- Melting point:
- 52-57 °C(lit.)
- Boiling point:
- 150°C 12mm
- Density
- 1.5728 (rough estimate)
- refractive index
- 1.5450 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Orange to Green
- BRN
- 3088698
- CAS DataBase Reference
- 1007-15-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 339679
- Product name
- 3′-Bromo-4′-fluoroacetophenone
- Purity
- 96%
- Packaging
- 25g
- Price
- $349
- Updated
- 2023/06/20
- Product number
- B2014
- Product name
- 3'-Bromo-4'-fluoroacetophenone
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $82
- Updated
- 2025/07/31
- Product number
- B2014
- Product name
- 3'-Bromo-4'-fluoroacetophenone
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $326
- Updated
- 2025/07/31
- Product number
- B691883
- Product name
- 3''-Bromo-4''-fluoroacetophone
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- JK178609
- Product name
- 3'-Bromo-4'-fluoroacetophenone
- Purity
- 97%
- Packaging
- 5g
- Price
- $71
- Updated
- 2021/12/16
3'-Bromo-4'-fluoroacetophenone Chemical Properties,Usage,Production
Chemical Properties
White to yellowish low melting soli
General Description
3′-Bromo-4′-fluoroacetophenone is also referred as 3-bromo-4-fluoro-acetophenone. Palladium-catalyzed amination of 3-bromo-4-fluoro-acetophenone has been reported.
Synthesis
403-42-9
176548-69-9
1007-15-4
Example A5: Synthesis of 1-(3,5-dibromo-4-fluorophenyl)ethan-1-one and 1-(3-bromo-4-fluorophenyl)ethan-1-one 69 g (0.5 mol) of 4-fluoroacetophenone was slowly added dropwise to 200.0 g (1.5 mol) of finely powdered aluminum and heated to 70 °C with stirring. The reaction temperature was maintained at 75-80 °C for 20 min, followed by the slow addition of 184 g (1.15 mol) of bromine at the same temperature over a period of 2.5 hours. After completion of the reaction, the mixture was heated to 90 °C and maintained for 3 hours. After cooling, decolorization was carried out and then the mixture was partitioned between water and tert-butyl methyl ether. The organic phase was separated to give 130 g of brownish black oil. The oily substance was separated by column chromatography on toluene, using toluene as eluent, to give a two-part product: a) 41.2 g (28% of theoretical yield) of colorless crystals with a melting point of 59-62 °C and an Rf = 0.53 (toluene). Identified by spectral analysis as 1-(3,5-dibromo-4-fluorophenyl)-1-ethanone. IR (KBr): 1685 (C=O) cm?1; MS: M? = 294/296/298 (Br?). b) 41.2 g (28% of the theoretical yield) colorless crystals, melting point 59-62 °C, Rf = 0.53 (toluene). b) 46.0 g (42% of theoretical yield) colorless crystals, melting point 52-55 °C, Rf = 0.41 (toluene). Identified by spectral analysis as 1-(3-bromo-4-fluorophenyl)-1-ethanone. IR (KBr): 1682 (C=O) cm?1; MS: M? = 216/218 (Br). c) 46.0 g (42% of theoretical yield) colorless crystals, melting point 52-55 °C, Rf = 0.41 (toluene).
References
[1] Patent: US7230001, 2007, B1. Location in patent: Page/Page column 67-68
3'-Bromo-4'-fluoroacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
3'-Bromo-4'-fluoroacetophenone Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
- 60
View Lastest Price from 3'-Bromo-4'-fluoroacetophenone manufacturers
- Product
- 3'-Bromo-4'-fluoroacetophenone 1007-15-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-09
- Product
- 3'-Bromo-4'-fluoroacetophenone 1007-15-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000KG
- Release date
- 2024-07-16
- Product
- 3"-Bromo-4"-fluoroacetophenone 1007-15-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11