L-2-AMINO-4-SULFOBUTYRIC ACID
- Product Name
- L-2-AMINO-4-SULFOBUTYRIC ACID
- CAS No.
- 14857-77-3
- Chemical Name
- L-2-AMINO-4-SULFOBUTYRIC ACID
- Synonyms
- L-HOMOCYSTEIC ACID;
L -Homocysteic acid;L-2-AMINO-4-SULFOBUTYRIC ACID;(S)-2-Amino-4-sulfobutanoic acid;Butanoic acid, 2-amino-4-sulfo-, (2S)- - CBNumber
- CB4173807
- Molecular Formula
- C4H9NO5S
- Formula Weight
- 183.18
- MOL File
- 14857-77-3.mol
L-2-AMINO-4-SULFOBUTYRIC ACID Property
- Density
- 1.638±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- form
- powder
- pka
- 1.40±0.50(Predicted)
- color
- white to off-white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- H9633
- Product name
- L-Homocysteic acid
- Packaging
- 25mg
- Price
- $66.8
- Updated
- 2025/07/31
- Product number
- H9633
- Product name
- L-Homocysteic acid
- Packaging
- 1g
- Price
- $1230
- Updated
- 2025/07/31
- Product number
- H9633
- Product name
- L-Homocysteic acid
- Packaging
- 250mg
- Price
- $371
- Updated
- 2025/07/31
- Product number
- H9633
- Product name
- L-Homocysteic acid
- Packaging
- 100mg
- Price
- $182
- Updated
- 2023/06/20
- Product number
- AAA0003869
- Product name
- L-HOMOCYSTEIC ACID
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $586.12
- Updated
- 2021/12/16
L-2-AMINO-4-SULFOBUTYRIC ACID Chemical Properties,Usage,Production
Uses
L-Homocysteic acid has been used to study hydrogen peroxide-mediated changes in physiological and pathological conditions in the nervous system.
Definition
ChEBI: A homocysteic acid with L-configuration.
Biochem/physiol Actions
L-Homocysteic acid (L-HCA) is an endogenous neurotransmitter ligand of NMDA (N-methyl-D-aspartate) receptors. It is an analog of glutamate and competitively suppresses glutamate-cystine (xc-) antiporter function in neurons, causing decrease in cysteine uptake.
in vivo
L-Homocysteic acid (intraperitoneal injection, 4-11 mmol/kg) elicits seizures in rats during early postnatal development[4].
L-Homocysteic acid (intraperitoneal injection, 100-1500 mg/kg) partially substitutes for NMDA, producing maximum values of 61-67% NMDA-lever responding at doses of 1000 and 560 mg/kg, respectively in Sprague-Dawley rats[5].
| Animal Model: | Male albino rats of the Wistar strain[4] |
| Dosage: | 4, 5.5, 8, 11 mM/kg |
| Administration: | Intraperitoneal injection, daily for 14 days |
| Result: | Induced flexion seizures at 4 mmol/kg. Led to intense tail flicking, pivoting, and locomotion. Decreased ECoG (electrocorticograms) activity for 5-9 min. |
IC 50
NMDA Receptor: 14 μM (EC50)
L-2-AMINO-4-SULFOBUTYRIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
L-2-AMINO-4-SULFOBUTYRIC ACID Suppliers
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