ChemicalBook > CAS DataBase List > Dorzolamide

Dorzolamide

Product Name
Dorzolamide
CAS No.
120279-96-1
Chemical Name
Dorzolamide
Synonyms
C06969;DORZOLAMIDE;4S,6S-Dorzolamide;Dorzolamide-d5 Maleate;Dorzolamide >=98% (HPLC);Dorzalamide hydrochloride;DORZOLAMIDE(SUBJECTTOPATENTFREE);Dorzolamide Impurity A Hydrochloride;(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-7,;7-dioxide-4H-Thieno[2,3-b]thiopyran-2-sulfonamide/ Dorzolamide
CBNumber
CB4174657
Molecular Formula
C10H16N2O4S3
Formula Weight
324.44
MOL File
120279-96-1.mol
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Dorzolamide Property

Boiling point:
575.8±60.0 °C(Predicted)
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: soluble5mg/mL (clear solution, warmed)
pka
pKa 6.35 (Uncertain);8.50 (Uncertain)
form 
powder
color 
white to beige
optical activity
[α]/D -25 to -35°, c = 1 in methanol
CAS DataBase Reference
120279-96-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
RTECS 
XJ9095169
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0468
Product name
Dorzolamide
Purity
≥98% (HPLC)
Packaging
10mg
Price
$96.7
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0468
Product name
Dorzolamide
Purity
≥98% (HPLC)
Packaging
50mg
Price
$393
Updated
2024/03/01
TRC
Product number
D535103
Product name
Dorzolamide
Packaging
25mg
Price
$530
Updated
2021/12/16
TRC
Product number
D535103
Product name
Dorzolamide
Packaging
50mg
Price
$1035
Updated
2021/12/16
TRC
Product number
D535103
Product name
Dorzolamide
Packaging
100mg
Price
$1705
Updated
2021/12/16
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Dorzolamide Chemical Properties,Usage,Production

Uses

Carbonic anhydrase inhibitor.

Uses

Dorzolamide is an intermediate in synthesizing N-Acetyl Dorzolamide (A173640), a useful synthetic compound.

Definition

ChEBI: 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration . A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension.

brand name

Trusopt (Merck).

Dorzolamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dorzolamide manufacturers

Career Henan Chemical Co
Product
Dorzolamide 120279-96-1
Price
US $2.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100kg
Release date
2020-01-07

120279-96-1, DorzolamideRelated Search:


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  • DORZOLAMIDE(SUBJECTTOPATENTFREE)
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  • 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S-trans)-
  • 4S,6S-Dorzolamide
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  • (4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-7,
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  • 7-dioxide-4H-Thieno[2,3-b]thiopyran-2-sulfonamide/ Dorzolamide
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  • 120279-96-1
  • 12079-96-1
  • C10H16N2O4S3