Ceramide

Uses

Product Name: Ceramide
CAS No.: 104404-17-3
Chemical Name: Ceramide
Synonyms: CERAMIDE;N-oleoylsphingosine;Ceramide (d18:1/16:0);Ceramide (d18:1/12:0);Ceramide (d18:1/18:0);Ceramide (d18:1/20:0);Ceramide (d18:1/22:0);Ceramide (d18:1/24:0);Ceramide (d18:1/25:0);Ceramide (d18:1/26:0)
CBNumber: CB8764212
Molecular Formula: C34H66NO3R
Formula Weight: 536.89
MOL File: 104404-17-3.mol

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Ceramide Property

InChIKey: XJRPTDNTEPSGLZ-UHFFFAOYSA-N
SMILES: C(OC(C)=O)(C(CCCCCCCCCCCCCC)OC(C)=O)C(CO)NC(CCCCCCCCCCCCCCCCCCCCCCCCC)=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: LIP0004196
Product name: CERAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $755.06
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIP0004196
Product name: CERAMIDE
Purity: 95.00%
Packaging: 25MG
Price: $1190.07
Updated: 2021/12/16

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Ceramide Chemical Properties,Usage,Production

Uses

Ceramides are a class of complex sphingolipids that act as second messengers in processes such as cell growth, differentiation, stress response, inflammatory signal transduction, and apoptosis. They are associated with the pathogenesis of various diseases and can serve as biomarkers for disease detection and prognosis, playing a significant role in diseases such as coronary heart disease, myocardial infarction, and coronary atherosclerosis in cardiovascular diseases (CVD). Furthermore, they possess moisturizing and skin-repairing properties and are widely used in skin care and cosmetic formulations.

Definition

ChEBI: N-octadecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It has a role as a mouse metabolite. It is a N-acylsphingosine and a N-stearoyl-sphingoid base. It is functionally related to an octadecanoic acid.

benefits

Ceramides are lipids, which are fatty acids that are produced in the sebaceous glands. Ceramides help to moisturise and strengthen the protective skin moisture barrier, and protect the skin from external aggressors such as weather and pollution.

Mode of action

Topically applied ceramide (Cer) could improve barrier function in three possible ways: (1) Cer in an appropriate formulation constructs (lamellar) liquid crystalline and/or gel structures; (2) Cer is likely incorporated into lamellar bilayer structures in the SC to repair incompetent bilayer structures; and/or (3) Cer penetrates into nucleated layers of the epidermis and becomes a precursor to endogenous Cer synthesis following hydrolysis to the sphingoid base and FA. In addition, Cer absorbed into nucleated layers of the epidermis could suppress KC proliferation and promote differentiation. Because Cer production is increased during KC differentiation, the stimulation of KC differentiation can increase de novo Cer production, thereby contributing to barrier formation[1].

References

[1] Kyong-Oh Shin. “Exogenous Ceramide Serves as a Precursor to Endogenous Ceramide Synthesis and as a Modulator of Keratinocyte Differentiation.” Cells (2022).

Ceramide Preparation Products And Raw materials

Raw materials

Preparation Products

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Ceramide Suppliers

China 69 Japan 1 Switzerland 1 United Kingdom 3 United States 4 Global 78

Xi'an Chaobang Biotechnology Co. , Ltd.

Tel: 13324615505
Email: 976908044@qq.com
Country: China
ProdList: 239
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

Yichang Zhongyitai Trading Co., Ltd.

Tel: 0717-6449896 13886658719
Fax: 0717-6558598
Email: root@zhongyitai.com
Country: China
ProdList: 1978
Advantage: 58

Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.

Tel: 027-59420981,18702770802
Fax: 027-83322098
Country: China
ProdList: 1975
Advantage: 50

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6468
Advantage: 55

INTERCHEMIE NANJING PHARMATECH CO., LTD

Tel: 13656237714 13656237714;
Fax: 0512-65852853
Email: xiaokunfu@kyyykj.com
Country: China
ProdList: 295
Advantage: 55

JinJin Le Chemical Co., Ltd

Tel: 18001959627(微信同号) 18001959627
Email: jjlchem2@163.com
Country: China
ProdList: 9981
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

Shaanxi billion Kang Long biological technology co., LTD

Tel: 17791478691
Fax: 4009024560
Email: yklbiotech@163.com
Country: China
ProdList: 317
Advantage: 58

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View Lastest Price from Ceramide manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Ceramide 104404-17-3
Price: US $79.00-38.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-11-18

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: CERAMIDE NS/CERAMIDE NG 104404-17-3
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 90%
Supply Ability: 2000kgs
Release date: 2025-02-23

BINBO BIOLOGICAL CO.,LTD

Product: Ceramide 104404-17-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 10%
Supply Ability: 1000 kg
Release date: 2024-04-08

104404-17-3, CeramideRelated Search:

Ferric acetylacetonate Cupric acetylacetonate METHYL ISOCYANOACETATE Ethyl isocyanoacetate Ceramide COBALT(II) ACETYLACETONATE PHENYLSELENOL TERT-BUTYL ISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE N-BUTYLISOCYANIDE Aluminum acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) SALCOMINE Benzyl isocyanide

Ceramide?(saturated,?unsaturated?and?a-OH?fatty?acids)

Ceramide (d18:1/12:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)dodecanamide

Ceramide (d18:1/16:0)

(2S,3R,4E)-2-acylamino-1,3-octadec-4-enediol

1-O-[O-(N-Acetyl-ALPHA-neuraminosyl)-(2.fwdarw.3)-O-[O-B-D-galactopyranosyl

N-octadecanoylsphingosine

N-icosanoylsphingosine

N-docosanoylsphingosine

N-hexacosanoylsphingosine

N-oleoylsphingosine

Ceramide/rice bran extract

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)hexadecanamide

Ceramide (d18:1/18:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)octadecanamide

Ceramide (d18:1/20:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)icosanamide

Ceramide (d18:1/22:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)docosanamide

Ceramide (d18:1/24:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)tetracosanamide

(Z)-N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)tetracos-15-enamide

Ceramide (d18:1/24:1(15Z))

Ceramide (d18:1/25:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)pentacosanamide

Ceramide (d18:1/26:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)hexacosanamide

(Z)-N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)hexacos-17-enamide

Ceramide (d18:1/26:1(17Z))

(Z)-N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)octadec-9-enamide

Ceramide (d18:1/9Z-18:1)

CERAMIDE ISO 9001：2015 REACH

CERAMIDE

104404-17-3

C30H59NO3

C40H79NO3

C42H83NO3

C43H85NO3

C44H87NO3

C44H85NO3

C48H93NO6